KEGG   REACTION: R08663Help
Entry
R08663                      Reaction                               

Name
L-valine,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)
Definition
L-Valine + 2 Oxygen + 2 NADPH + 2 H+ <=> (E)-2-Methylpropanal oxime + 3 H2O + 2 NADP+ + CO2
Equation
C00183 + 2 C00007 + 2 C00005 + 2 C00080 <=> C03219 + 3 C00001 + 2 C00006 + C00011
Comment
three-step reaction (see R10031+R10032+R10033)
The enzyme can also accept L-isoleucine as substrate, with a lower activity.(1.14.13.117)
3step reaction (similar to R00730+R04460+R07190)
RPair
C00005_C00006 cofac [RC:RC00001]
C00001_C00007 cofac
C00011_C00183 leave
C00183_C03219 main [RC:RC02339]
C00007_C03219 leave
Enzyme
Pathway
Glucosinolate biosynthesis
Biosynthesis of secondary metabolites
2-Oxocarboxylic acid metabolism
Orthology
K13401  
valine N-monooxygenase [EC:1.14.13.118]

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