KEGG   REACTION: R08901Help
Entry
R08901                      Reaction                               

Name
2'''-acetyl-6'''-hydroxyneomycin-C hydrolase (acetate-forming)
Definition
2'''-N-Acetyl-6'''-deamino-6'''-hydroxyneomycin C + H2O <=> 6'''-Deamino-6'''-hydroxyneomycin C + Acetate
Equation
Reaction class
C17587_C17588
C00033_C17587
Enzyme
Pathway
Neomycin, kanamycin and gentamicin biosynthesis
Biosynthesis of antibiotics
Orthology
K17078  
2'-N-acetylparomamine deacetylase / 2'''-acetyl-6'''-hydroxyneomycin deacetylase [EC:3.5.1.112 3.5.1.113]
Reference
1  [PMID:17226887]
Truman AW, Huang F, Llewellyn NM, Spencer JB.
Characterization of the enzyme BtrD from Bacillus circulans and revision of its functional assignment in the biosynthesis of butirosin.
Angew. Chem. Int. Ed. Engl. 46 (2007) 1462-4.

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