KEGG   REACTION: R08901Help
Entry
R08901                      Reaction                               

Name
2'''-acetyl-6'''-hydroxyneomycin-C hydrolase (acetate-forming)
Definition
2'''-N-Acetyl-6'''-deamino-6'''-hydroxyneomycin C + H2O <=> 6'''-Deamino-6'''-hydroxyneomycin C + Acetate
Equation
RPair
C00001_C00033 leave
C17587_C17588 main [RC:RC00166]
C00033_C17587 main [RC:RC00300]
Enzyme
Pathway
Butirosin and neomycin biosynthesis
Biosynthesis of secondary metabolites
Orthology
K17078  
2'-N-acetylparomamine deacetylase / 2'''-acetyl-6'''-hydroxyneomycin deacetylase [EC:3.5.1.112 3.5.1.113]
Reference
1  [PMID:17226887]
Truman AW, Huang F, Llewellyn NM, Spencer JB.
Characterization of the enzyme BtrD from Bacillus circulans and revision of its functional assignment in the biosynthesis of butirosin.
Angew. Chem. Int. Ed. Engl. 46 (2007) 1462-4.

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