KEGG   REACTION: R09543Help
Entry
R09543                      Reaction                               

Name
S-adenosyl-L-methionine:malonyl-[acyl-carrier protein] O-methyltransferase
Definition
S-Adenosyl-L-methionine + Malonyl-[acyl-carrier protein] <=> S-Adenosyl-L-homocysteine + Malonyl-[acp] methyl ester
Equation
Comment
Malonyl-[acp] is a far better acceptor of methyl groups from S-adenosyl-L-methionine than was malonyl-CoA.
RPair
C00019_C00021 main [RC:RC00003]
C01209_C19673 main [RC:RC00460]
C00019_C19673 trans
Enzyme
Pathway
Biotin metabolism
Metabolic pathways
Module
M00572  
Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP
Orthology
K02169  
malonyl-CoA O-methyltransferase [EC:2.1.1.197]
Reference
1  [PMID:22965231]
Lin S, Cronan JE.
The BioC O-Methyltransferase Catalyzes Methyl Esterification of Malonyl-Acyl Carrier Protein, an Essential Step in Biotin Synthesis.
J. Biol. Chem. 287 (2012) 37010-20.

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