KEGG   Rattus norvegicus (rat): 114495Help
Entry
114495            CDS       T01003                                 

Gene name
Map2k6, Mkk6
Definition
mitogen-activated protein kinase kinase 6 (EC:2.7.12.2)
Orthology
K04433  
mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
MAPK signaling pathway
Rap1 signaling pathway
Osteoclast differentiation
Toll-like receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Amyotrophic lateral sclerosis (ALS)
Toxoplasmosis
Influenza A
Epstein-Barr virus infection
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    114495 (Map2k6)
   04010 MAPK signaling pathway
    114495 (Map2k6)
   04668 TNF signaling pathway
    114495 (Map2k6)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    114495 (Map2k6)
   04664 Fc epsilon RI signaling pathway
    114495 (Map2k6)
  Endocrine system
   04912 GnRH signaling pathway
    114495 (Map2k6)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    114495 (Map2k6)
  Development
   04380 Osteoclast differentiation
    114495 (Map2k6)
 Human Diseases
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    114495 (Map2k6)
  Infectious diseases
   05164 Influenza A
    114495 (Map2k6)
   05169 Epstein-Barr virus infection
    114495 (Map2k6)
   05145 Toxoplasmosis
    114495 (Map2k6)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     114495 (Map2k6)
Protein kinases [BR:rno01001]
 Serine/threonine protein kinases: STE group
  STE7 family
   114495 (Map2k6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
10q32.1
AA seq 334 aa AA seqDB search
MSQSKGKKRNPGLKIPREAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSADFVDFTSQCLKKNSK
ERPTYPELMQHPFFTVHEAKAADVASFVKLILGD
NT seq 1005 nt NT seq  +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccccggccttaagattccaagggaagcgttt
gaacaacctcagaccagttccacgccgcctcgggatttagactccaaggcttgcatttct
attggaaaccagaactttgaggtgaaggccgatgacttggagcctatagtggagctggga
cgaggtgcgtacggggtggtggagaagatgcgtcacgtgcccagcgggcagatcatggcg
gtgaagcggatacgggccacagttaatagccaggagcagaaacggctactgatggatctg
gatgtttctatgaggacagtggactgtccgtttaccgtgaccttctatggtgcactcttc
cgggagggcgatgtgtggatctgcatggagctcatggatacgtcactagataaattctac
aaacaagttattgataaaggccaaacaattccagaagatatcttagggaagatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctctctgttatccatcgagatgtc
aagccttcaaatgtgctcattaacacgctgggccaagtgaagatgtgtgactttggaatc
agcggctacctggtagactctgttgcgaaaacgatcgatgccggttgcaaaccatacatg
gctcctgaacgaataaatccagagctcaaccagaaggggtacagtgtgaagtctgacatt
tggagtctgggcatcaccatgattgagctggccatcctccggtttccctatgattcttgg
ggaacgcccttccagcagctaaaacaggtggtagaagagccgtctccacaactcccagcg
gacaagttctctgctgacttcgttgactttacctcacagtgcttgaagaaaaattccaaa
gaacggcccacgtatccagagcttatgcaacatccatttttcaccgtccatgaagccaaa
gcagcagatgtggcgtctttcgtaaaactgatactcggggactaa

DBGET integrated database retrieval system