KEGG   Rattus norvegicus (rat): 117269
Entry
117269            CDS       T01003                                 
Symbol
Rps6ka2
Name
(RefSeq) ribosomal protein S6 kinase alpha-2
  KO
K04373  ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04114  Oocyte meiosis
rno04150  mTOR signaling pathway
rno04714  Thermogenesis
rno04720  Long-term potentiation
rno04722  Neurotrophin signaling pathway
rno04914  Progesterone-mediated oocyte maturation
rno04931  Insulin resistance
rno05135  Yersinia infection
rno05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    117269 (Rps6ka2)
   04150 mTOR signaling pathway
    117269 (Rps6ka2)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    117269 (Rps6ka2)
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    117269 (Rps6ka2)
  09156 Nervous system
   04720 Long-term potentiation
    117269 (Rps6ka2)
   04722 Neurotrophin signaling pathway
    117269 (Rps6ka2)
  09159 Environmental adaptation
   04714 Thermogenesis
    117269 (Rps6ka2)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    117269 (Rps6ka2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    117269 (Rps6ka2)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    117269 (Rps6ka2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    117269 (Rps6ka2)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:rno03019]
    117269 (Rps6ka2)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     117269 (Rps6ka2)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   117269 (Rps6ka2)
Messenger RNA biogenesis [BR:rno03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     117269 (Rps6ka2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Kdo Pkinase_fungal Pkinase_C APH Haspin_kinase RIO1 YrbL-PhoP_reg
Other DBs
NCBI-GeneID: 117269
NCBI-ProteinID: NP_476469
RGD: 620676
Ensembl: ENSRNOG00000013194
UniProt: A6KK46 F1M7N7
Position
1:55178988..55454271
AA seq 733 aa
MELNMKKFTVRRFFSVYLRKKSRSKSSSLSRLEEEGIVKEIDISSHVKEGFEKADPSQFE
LLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPF
IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGLGI
IYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSA
DWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSAEAQSLLRALFKRNPCN
RLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDS
PGVPPSANAHHLFRGFSFVASSLVQEPSQQDVPKAPIHPIVQQLHGNNIHFTDGYEIKED
IGVGSYSVCKRCVHKATDAEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGK
YVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHSQGVVHRDLKPSNILY
MDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDVWSLGIL
LYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPQQR
LTAVQVLKHPWIVNREYLSQNQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSSLA
QRRGMKRLTSTRL
NT seq 2202 nt   +upstreamnt  +downstreamnt
atggagctgaacatgaagaagttcacggtgcgcaggttcttctcagtgtacctgcgcaag
aagtcgcgctccaagagctccagtctgagtcgcctcgaggaagaaggcatcgtgaaggag
attgacattagcagccatgtgaaggaaggcttcgagaaggcagacccctcccagttcgag
ctgctaaaagttttaggacaagggtcgtatggaaaggtgttcttggtgaggaaagtcaca
ggatcggatgctggtcagctctacgccatgaaagtcctgaagaaagccaccttgaaagtg
cgggaccgggtccggtctaagatggagagagatatcctggcagaggtgaatcaccctttc
atcgtcaagctgcattacgcctttcagaccgaaggcaagctctacctgatcctggacttc
ctgcggggaggagacctcttcaccaggctttccaaagaggtgatgtttacggaggaggat
gttaagttctacctggctgagctggccttggctctggaccacctccacggcctagggatc
atctacagggatctgaagcctgaaaatatcctcctggatgaagagggacatattaagatc
acagattttggcttgagcaaggaggccatcgaccatgacaagagagcctattcattttgt
gggactattgaatacatggcgcccgaggtggtgaaccggcgtggacacacacagagtgct
gactggtggtcctttggtgtgctcatgttcgagatgctcacaggatccctgccgtttcag
gggaaggacaggaaggaaacaatggccctcatcctcaaagccaagctgggcatgcctcag
ttcctcagtgcggaggcacagagcctgctgagagcccttttcaagcggaatccctgtaac
cggctaggtgctggtgttgacggagtggaggaaattaaacgtcacccgttctttgtcacc
atagactggaataagctgtatcgcaaggaaatcaagccacccttcaagccagcagtggga
aggcctgaggacaccttccactttgaccccgagtttactgcaaggacccccacagactct
cctggtgtccccccaagtgcaaacgcccaccacctgttcagggggttcagctttgtggcc
tccagcctggtccaggagccttcacagcaagacgtgcccaaggcccccattcacccgatt
gtgcagcagttacatgggaacaatatccacttcactgatggctacgagatcaaggaggac
atcggggtgggctcctactcagtgtgcaagcggtgtgtacacaaagccacggatgccgag
tacgccgtgaagatcatcgataagagcaaaagggatccctcagaggagattgagatcctc
ctgcggtatggccaacaccccaacatcatcaccctaaaagatgtctatgatgatggaaaa
tacgtatacctggtgatggagctcatgcgaggtggggagctgctggaccgcatcctccgc
cagcggtgcttctcagagcgggaggccagtgatgtgctgtacaccatcgccaggaccatg
gactacctgcactcccaaggggttgttcatcgggacctgaaaccaagtaacattctgtac
atggatgaatctggaaaccccgaatctatccgcatctgtgactttgggtttgccaaacag
ctgcgagcagaaaatggactgctcatgaccccctgctatactgcgaacttcgtggctcct
gaggtcctgaagcggcaaggctacgacgcagcgtgtgatgtctggagcctgggaatcctg
ctgtacaccatgctggctgggttcaccccttttgctaatgggccagacgatacccccgag
gagattctggcgaggattggcagtgggaagtacgccctttctggaggaaactgggactcc
atatcggatgcagcaaaggacgtcgtgtccaagatgctccacgtggacccgcagcaacgc
ctaacagcagttcaagtgttgaagcacccatggatcgtgaacagagagtacctatcccaa
aaccagctgagcagacaggacgtccatctagtgaagggtgccatggcagccacctacttt
gctctgaacaggaccccacaggcgccgaggctggagcctgtgctctcctctagcttggcc
caacgcagaggcatgaagagactcacgtctacccggttgtag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (7)   
   UniProt (2)   
   RefSeq(pep) (5)   
DNA sequence (7)   
   RefSeq(nuc) (5)   
   GenBank (1)   
   EMBL (1)   
Protein domain (11)   
   Pfam (11)   
All databases (47)   

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