KEGG R.norvegicus: 161452

Rattus norvegicus (rat): 161452

Entry

161452 CDS R.norvegicus

Gene name Lef1

Definition lymphoid enhancer binding factor 1

Orthology K04492 lymphoid enhancer-binding factor 1

Pathway rno04310 Wnt signaling pathway
rno04520 Adherens junction
rno04916 Melanogenesis
rno05200 Pathways in cancer
rno05210 Colorectal cancer
rno05213 Endometrial cancer
rno05215 Prostate cancer
rno05216 Thyroid cancer
rno05217 Basal cell carcinoma
rno05221 Acute myeloid leukemia
rno05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Class Genetic Information Processing; Transcription; Transcription factors
Environmental Information Processing; Signal Transduction; Wnt
signaling pathway [PATH:rno04310]
Cellular Processes; Cell Communication; Adherens junction
[PATH:rno04520]
Organismal Systems; Endocrine System; Melanogenesis [PATH:rno04916]
Human Diseases; Cancers; Pathways in cancer [PATH:rno05200]
Human Diseases; Cancers; Colorectal cancer [PATH:rno05210]
Human Diseases; Cancers; Thyroid cancer [PATH:rno05216]
Human Diseases; Cancers; Acute myeloid leukemia [PATH:rno05221]
Human Diseases; Cancers; Basal cell carcinoma [PATH:rno05217]
Human Diseases; Cancers; Prostate cancer [PATH:rno05215]
Human Diseases; Cancers; Endometrial cancer [PATH:rno05213]
Human Diseases; Circulatory Diseases; Arrhythmogenic right
ventricular cardiomyopathy (ARVC) [PATH:rno05412]

SSDB

Motif Pfam: CTNNB1_binding HMG_box MAT_Alpha1
PROSITE: HMG_BOX_2

Other DBs NCBI-GI: 18426860
NCBI-GeneID: 161452
RGD: 620241
RATMAP: ENSRNOG00000010121
Ensembl: ENSRNOG00000010121
UniProt: Q9QXN1

Position 2q34-q45

AA seq 397 aa
MPQLSGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESE
IIPASNGHEVVGQTQSSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNS
DPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSEVNPKQ
GMSRHPPAPEMPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQAYPSSLSGDTSMSRF
SHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPEHEQRKEQEPKRPHIKKP
LNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQL
YPGWSARDNYGKKKKRKREKLQESTSGTGPRMTAAYI

NT seq 1194 nt +upstreamnt +downstreamnt
atgccccaactttccggaggaggcggtgggggggacccggaactctgcgccaccgatgag
atgatccccttcaaggacgagggcgatccccagaaggagaagattttcgccgagatcagt
caccccgaagaggagggcgacttagcagacatcaagtcatccttggtaaacgagtccgaa
atcatcccagccagcaacgggcatgaggtggtcggacaaacacagtcctctcaggagccc
taccacgacaaggccagagagcacccggatgacggaaagcatccggacggaggtctatat
aacaagggcccctcctactccagttactctggctacatcatgatgcccaatatgaatagc
gacccatacatgtcaaatggatccctttctccacccatcccgaggacctcaaataaagtg
ccggtggtgcagccatctcacgcggtccaccccctcacgcccctcatcacgtacagcgac
gagcacttttctccagggtctcacccgtcacacatcccgtcagaggtcaaccccaagcaa
ggcatgtctagacacccaccagctcctgaaatgcccaccttctaccccctgtctccaggc
ggcgttggacagatcaccccacccctcggctggcaaggtcagcctgtttatcccatcacg
ggtgggttcaggcaagcctacccatcttcactttcaggggacacttccatgtccaggttt
tcccatcacatgattcctgggccccctggcccccacacaactggcatccctcatccagca
attgtaacacctcaggtcaaacaggagcacccccacacggacagcgacctaatgcacgtg
aagcctgagcacgaacagagaaaggaacaggagcctaaaagacctcatattaagaagcct
ctgaatgctttcatgttatacatgaaagaaatgagggcgaatgtcgtagccgagtgtacg
ctaaaggagagcgcagctatcaaccagatcctgggcagaaggtggcacgccctctcccgg
gaagagcaggccaaatattatgaattagcgcggaaagaaagacagctacatatgcagctc
tatccaggctggtcagcgagagacaattatggcaagaagaagaagaggaagagagagaag
ctacaggaatctacttcaggtacaggtcccagaatgacagctgcctacatctga

All links

Pathway (11)   
   KEGG PATHWAY (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (4)   
   UNIGENE (1)   
   ENSEMBL-RNO (1)   
   RATMAP-RNO (1)   
   RGD-RNO (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (1)   
   IPI (3)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (4)   
   Pfam (3)   
   PROSITE (1)   
All databases (34)

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