KEGG   Rattus norvegicus (rat): 170897Help
Entry
170897            CDS       T01003                                 

Gene name
Sphk1
Definition
(RefSeq) sphingosine kinase 1 (EC:2.7.1.91)
  KO
K04718  
sphingosine kinase [EC:2.7.1.91]
Organism
rno  Rattus norvegicus (rat)
Pathway
Sphingolipid metabolism
Metabolic pathways
Calcium signaling pathway
Sphingolipid signaling pathway
Phospholipase D signaling pathway
VEGF signaling pathway
Fc gamma R-mediated phagocytosis
Tuberculosis
Module
Sphingosine degradation
Brite
KEGG Orthology (KO) [BR:rno00001]
 Metabolism
  Lipid metabolism
   00600 Sphingolipid metabolism
    170897 (Sphk1)
 Environmental Information Processing
  Signal transduction
   04370 VEGF signaling pathway
    170897 (Sphk1)
   04020 Calcium signaling pathway
    170897 (Sphk1)
   04072 Phospholipase D signaling pathway
    170897 (Sphk1)
   04071 Sphingolipid signaling pathway
    170897 (Sphk1)
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    170897 (Sphk1)
 Human Diseases
  Infectious diseases
   05152 Tuberculosis
    170897 (Sphk1)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.91  sphinganine kinase
     170897 (Sphk1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
10q32.3
AA seq 383 aa AA seqDB search
MQPADCPRGLLPRPCRVLVLLNPRGGKGKALKLFQSRVRPLLEEAEVSFKLMLTERQNHA
RELVCAEELGHWDALAVMSGDGLMHEVVNGLMERPDWESAIQKPLCSLPGGSGNALAASL
NYYAGHEQVTNEDLLINCTLLLCCRQLSPMNLLSLHTASGRQLYSVLSLSWGFVADVDLE
SEKYRSLGEIRFTVGTFFRLASLRIYQGQLAYLPVGKAASKIPASSLAQKGPANTYLVPL
EEPVPPHWTVVPEQDFVLVLVLLHTHLSTEMFAAPMGRCEAGVMHLFYIRAGVSRAMLLR
LFLAMQKGKHMDLDCPYLVHVPVVAFRLEPRNQRGVFSVDGELMVCEAVQGQVHPNYLWM
VSGSSDSPSGRDSQRRPPPEEPI
NT seq 1152 nt NT seq  +upstreamnt  +downstreamnt
atgcaaccagcagactgtccccggggactgctcccacggccatgcagagtgttggtgctg
ctgaacccccggggtggcaagggcaaggctctgaagctctttcagagccgtgtgcggccc
cttctggaggaggctgaggtatcctttaaactgatgctcaccgaacggcagaaccatgcc
agggagctggtgtgtgcagaagaactgggtcactgggatgccttggcggtcatgtccggt
gacggtctgatgcacgaggtggtgaatgggctaatggaacgacctgactgggagagtgcc
atccagaaacccctatgtagcctccctggaggctctggcaatgcgctggcagcttctttg
aactactatgctgggcacgagcaggtcactaatgaagatctcctgatcaactgcacactg
ctgttatgctgccggcagctgtcacccatgaatctgctgtccctgcacaccgcttccgga
cggcaactctattctgttctcagtctgtcctggggtttcgttgctgacgtggacttggag
agtgagaaatacaggagcttgggggagattcgtttcacggtgggaaccttttttcgccta
gcaagcctgcgcatttaccaaggccaactggcctaccttcctgtagggaaggctgcctct
aagatacctgcttcctcactggcacagaagggccctgccaacacatacctcgttcctctg
gaggagccagtgccacctcattggactgtggtgccagagcaggacttcgttctggtgctg
gtgctgcttcacacccacctgagcacagagatgtttgcagcacccatgggccgctgcgag
gctggtgttatgcatctgttctatatacgtgcgggggtgtcaagggccatgctgctgcgc
ctcttcctggccatgcagaagggcaagcatatggacctcgactgcccgtacttggttcat
gtgccagtggttgccttccgcctggaacccaggaaccagaggggagtgttttctgtggac
ggggagctgatggtgtgtgaagctgtgcagggccaagtgcacccaaactacctttggatg
gtctctggtagcagtgactccccgtccggccgggactcccagcggaggccacctccagaa
gaaccaatatga

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