KEGG T01003: 24310

Rattus norvegicus (rat): 24310

Entry

24310 CDS T01003

Gene name

Ace, Dcp1, StsRR92

Definition

angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 (EC:3.4.15.1)

Orthology

K01283

peptidyl-dipeptidase A [EC:3.4.15.1]

Organism

rno Rattus norvegicus (rat)

Pathway

rno04614	Renin-angiotensin system
rno05142	Chagas disease (American trypanosomiasis)
rno05410	Hypertrophic cardiomyopathy (HCM)

Class

Organismal Systems; Endocrine system; Renin-angiotensin system [PATH:rno04614]
Human Diseases; Cardiovascular diseases; Hypertrophic cardiomyopathy (HCM) [PATH:rno05410]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:rno05142]

SSDB

Motif

Pfam:

Peptidase_M2

Other DBs

NCBI-GI:

NCBI-GeneID:

RGD:

Ensembl:

UniProt:

Position

10q32.1

AA seq 1313 aa
MGAASGQRGRWPLSPPLLMLSLLLLLLLPPSPAPALDPGLQPGNFSADEAGAQLFADSYN
SSAEVVMFQSTAASWAHDTNITEENARLQEEAALINQEFAEVWGKKAKELYESIWQNFTD
QKLRRIIGSVQTLGPANLPLTQRLQYNSLLSNMSRIYSTGKVCFPNKTATCWSLDPELTN
ILASSRNYAKVLFAWEGWHDAVGIPLKPLYQDFTALSNEAYRQDGFSDTGAYWRSWYESP
SFEESLEHLYHQVEPLYLNLHAFVRRALHRRYGDKYINLRGPIPAHLLGDMWAQSWENIY
DMVVPFPDKPNLDVTSTMVQKGWNATHMFRVAEEFFTSLGLSPMPPEFWAESMLEKPADG
REVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHVQYYLQYKDLHVSLRRGANP
GFHEAIGDVLALSVSTPAHLHKIGLLDRVANDIESDINYLLKMALEKIAFLPFGYLVDQW
RWGVFSGRTPPSRYNYDWWYLRTKYQGICPPVARNETHFDAGAKFHIPSVTPYIRYFVSF
VLQFQFHQALCKEAGHQGPLHQCDIYQSTKAGAKLQQVLQAGCSRPWQEVLKDLVGSDAL
DASALMEYFQPVSQWLQEQNQRNGEVLGWPEYQWRPPLPDNYPEGIDLETDEAKANRFVE
EYDRTAKVLWNEYAEANWHYNTNITIEGSKILLQKNKEVSNHTLKYGTWAKTFDVSNFQN
STIKRIIKKVQNVDRAVLPPNELEEYNQILLDMETTYSVANVCYTNGTCLSLEPDLTNIM
ATSRKYEELLWVWKSWRDKVGRAILPFFPKYVDFSNKIAKLNGYSDAGDSWRSSYESDDL
EQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDL
VAPFPSAPSIDATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGRE
VVCHASAWDFYNGKDFRIKQCTSVNMEELVIAHHEMGHIQYFMQYKDLPVTFREGANPGF
HEAIGDVLALSVSTPKHLHSLNLLSSEGSGYEHDINFLMKMALDKIAFIPFSYLIDQWRW
RVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYIRYFISFII
QFQFHEALCRAAGHTGPLYKCDIYQSKEAGKLLADAMKLGYSKQWPEAMKIITGQPNMSA
SAIMNYFKPLTEWLVTENRRHGETLGWPEYTWTPNTARAEGSLPESSRVNFLGMYLEPQQ
ARVGQWVLLFLGVALLVATVGLAHRLYNIHNHHSLRRPHRGPQFGSEVELRHS

NT seq 3942 nt +upstreamnt +downstreamnt
atgggggccgcgtccggccagcgggggcggtggccgttgtcaccgccgctcttgatgctg
tcgctgctgctgctgctgctgctgccgccgtcgcccgccccggcgcttgaccctggattg
cagccgggcaacttttccgcggacgaggcaggggcgcagctcttcgctgacagctataac
tcgagtgccgaggtggtgatgttccagagcaccgcagccagctgggcgcacgacaccaac
atcacggaggagaatgcgcggctccaggaggaagcggccctgatcaaccaggagtttgca
gaggtctggggcaagaaggccaaggagctgtatgagtccatctggcagaacttcactgac
caaaagctgcgaaggatcatcggatccgtacagaccctaggacctgccaacctgcccctg
acccagcggctgcagtacaactctctgctaagcaacatgagcagaatctactccaccggc
aaggtctgcttccccaacaagactgccacctgctggtccctggacccagagctcaccaac
atcctggcttcctcacgaaactatgccaaggtgctgtttgcctgggaaggctggcatgat
gctgtgggtatcccactgaagcccctctatcaggactttactgccctcagtaatgaagcc
tacagacaagatggcttctcagacacaggagcctactggcgctcctggtatgagtccccc
tcctttgaagagagtttggagcatctctaccaccaagtcgagcccctctacctgaacctc
catgcctttgtccgtcgcgcactgcaccgccgctatggggacaaatacatcaatctcaga
ggtcctattcccgctcatctgctgggagacatgtgggcgcagagctgggagaacatttac
gacatggtagtgcctttcccggacaaacccaacctcgatgtcaccagtacaatggtacag
aagggctggaatgccacgcacatgttccgggtcgcagaggaattctttacctcgctgggg
ctctcccccatgcctccagagttctgggcggagtcgatgctggagaaaccagctgatgga
cgggaggtggtgtgccatgcctctgcgtgggacttctacaacaggaaggacttcaggatt
aagcagtgcacgcgggtcacgatggaccagctgtccacagtacaccacgagatgggccac
gtgcagtactatctccagtacaaggacctgcacgtctctctgcgtcgaggtgccaaccct
ggcttccacgaggccatcggggatgtactcgctctctctgtctctaccccagcacatctg
cacaaaattggcctgctagaccgtgttgccaatgacatagaaagtgacatcaattacttg
ctaaagatggccctagagaaaattgccttcttgccctttggttacctggtggaccagtgg
cgctggggggtcttcagtggacgtaccccaccctctcgctacaactacgactggtggtat
cttcgaaccaagtatcaggggatctgcccaccagttgctcggaatgaaacccattttgac
gctggggccaagtttcacatcccaagcgtgacaccatacatcaggtactttgtgagtttc
gtgctacagttccagttccatcaagcgctgtgcaaggaggcaggccaccagggtccacta
caccagtgtgacatctaccagtccaccaaggcaggggccaagctccaacaggtgctgcag
gctggctgctccaggccctggcaggaggtgctgaaggacctggtgggttcagatgcgctg
gatgccagtgcgctaatggagtacttccaaccagtaagccagtggctgcaggagcagaat
cagcggaatggcgaggtcctaggctggccggagtatcagtggcgtccaccgttaccagac
aactatccagagggaattgacctagagactgatgaagccaaggctaacaggttcgtggag
gagtatgaccggacagccaaggtgttgtggaacgaatacgcagaggccaactggcattat
aacaccaacattaccatagagggcagcaagatcctgcttcagaaaaacaaggaagtgtcc
aaccataccttgaaatatggcacctgggccaagacatttgacgtgagcaacttccagaac
tctaccatcaagcggatcataaagaaggttcagaacgtggaccgggcagtgctgcctccc
aacgagttagaagagtacaaccagatcctgctagacatggagacgacttacagtgtagcc
aatgtttgctacacaaatggcacttgtctgtcactggagcctgatctgacaaatataatg
gccacgtcccggaaatacgaagaattgctttgggtgtggaagagctggcgagacaaggtg
gggagagccatccttccctttttcccaaagtacgtggacttctccaacaagatcgccaag
ctcaacggctactctgatgcaggggattcctggagatcctcatatgagtccgacgacttg
gagcaagacctggaaaaactataccaggagctgcagccgctctacctgaacctgcatgcc
tatgtgcgccgctccctgcaccgccattatgggtctgagtacatcaacctggatggtccc
attcctgctcacctgctagggaacatgtgggcacagacttggtccaacatctatgacttg
gtggcacccttcccttccgcccccagtatagatgccacggaggccatgataaagcaggga
tggacacccagaaggatatttaaggaagctgacaatttttttacctccctggggctgtta
cctgtgccccctgagttctggaacaagtcaatgttagagaagccaaccgatgggagggag
gtggtgtgccatgcctcagcctgggacttctacaacggcaaggacttcaggatcaagcag
tgtacctctgtgaacatggaggaattggtgatagcccaccacgaaatgggccacatccag
tatttcatgcagtacaaagacttgcctgtgacctttcgggagggcgccaaccccggtttt
catgaggctattggagatgttttggctctgtctgtgtctacacccaagcatctacacagt
ctcaacctgctcagcagtgagggcagtggctacgagcatgacatcaactttctaatgaag
atggcccttgacaagatcgccttcatccccttcagctacctcattgaccagtggcgctgg
agggtctttgacggaagcatcaccaaggagaactacaaccaggagtggtggagtctcaga
ctgaagtaccagggtctctgccctccagtgcctagatcccaaggtgactttgacccaggg
tccaagttccacgttcctgcgaatgtgccatacatcaggtactttatcagcttcatcatc
cagttccagttccacgaggcactatgtcgcgcagccgggcacaccggccccctgtacaag
tgtgatatctaccaatccaaggaagcagggaagctgctggcagatgccatgaagttgggc
tacagtaagcagtggccagaagccatgaagataatcacaggccaacctaacatgtcagcc
tctgccattatgaattacttcaagccactgactgaatggctcgtcacagagaacaggaga
catggagagacactgggctggccggagtacacctggacaccaaacacggctcgtgcagaa
ggctccctcccagagtccagtcgcgtcaacttcctgggtatgtacctggaaccacagcag
gcccgtgtgggccagtgggtgctgctcttcctaggcgtcgccctgctggtggccaccgtg
ggtctcgcccaccgactctacaacatccataaccatcacagcctccgccggccccaccgt
gggccccagtttgggtccgaggtggagctcagacactcctga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (11)   
   UniGene (1)   
   ENSEMBL-RNO (1)   
   OC (1)   
   RGD (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
Protein domain (1)   
   Pfam (1)   
All databases (46)   

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