KEGG   Rattus norvegicus (rat): 24385Help
Entry
24385             CDS       T01003                                 

Gene name
Gck, GLUKA, RNGK2
Definition
glucokinase (EC:2.7.1.2)
Orthology
K12407  
glucokinase [EC:2.7.1.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
Glycolysis / Gluconeogenesis
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Butirosin and neomycin biosynthesis
Metabolic pathways
Carbon metabolism
Insulin signaling pathway
Insulin secretion
Prolactin signaling pathway
Type II diabetes mellitus
Maturity onset diabetes of the young
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Class
Metabolism; Overview; Carbon metabolism [PATH:rno01200]
Metabolism; Carbohydrate metabolism; Glycolysis / Gluconeogenesis [PATH:rno00010]
Metabolism; Carbohydrate metabolism; Galactose metabolism [PATH:rno00052]
Metabolism; Carbohydrate metabolism; Starch and sucrose metabolism [PATH:rno00500]
Metabolism; Carbohydrate metabolism; Amino sugar and nucleotide sugar metabolism [PATH:rno00520]
Metabolism; Biosynthesis of other secondary metabolites; Butirosin and neomycin biosynthesis [PATH:rno00524]
Organismal Systems; Endocrine system; Insulin secretion [PATH:rno04911]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:rno04910]
Organismal Systems; Endocrine system; Prolactin signaling pathway [PATH:rno04917]
Human Diseases; Endocrine and metabolic diseases; Type II diabetes mellitus [PATH:rno04930]
Human Diseases; Endocrine and metabolic diseases; Maturity onset diabetes of the young [PATH:rno04950]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
14q21
AA seq 498 aa AA seqDB search
MAMDTTRCGAQLLTLGTNKCTNACSLLCRAGTHNGHMNPRCRTEQAAATQLPTCRVQLLL
NYHVEGRADPGRVPAAGGRPEEGDEPDAEGDGPWPEAGDPRGEVGDFLSLDLGGTNFRVM
LVKVGEGEAGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLG
FTFSFPVRHEDLDKGILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTV
ATMISCYYEDRQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELD
EFLLEYDRMVDESSANPGQQLYEKIIGGKYMGELVRLVLLKLVDENLLFHGEASEQLRTR
GAFETRFVSQVESDSGDRKQIHNILSTLGLRPSVTDCDIVRRACESVSTRAAHMCSAGLA
GVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPNCEITFIESEEGSGR
GAALVSAVACKKACMLAQ
NT seq 1497 nt NT seq  +upstreamnt  +downstreamnt
atggctatggatactacaaggtgtggagcccagttgttgactctgggcaccaacaaatgc
acgaatgcatgctccctgctgtgcagagcgggtactcacaacgggcacatgaaccctcgc
tgccgaacagagcaggcggccgccacacagctgcccacctgcagagtccagctactcttg
aactatcatgtggagggtcgagcagatcctggcagagttccagctgcaggaggaagacct
gaagaaggtgatgagccggatgcagaaggagatggaccgtggcctgaggctggagaccca
cgaggagaagtcggagactttctctccttagacctgggaggaaccaacttcagagtgatg
ctggtcaaagtgggagagggggaggcagggcagtggagcgtgaagacaaaacaccagatg
tactccatccccgaggacgccatgacgggcactgccgagatgctctttgactacatctct
gaatgcatctctgacttccttgacaagcatcagatgaagcacaagaaactgcccctgggc
ttcaccttctccttccctgtgaggcacgaagacctagacaagggcatcctcctcaattgg
accaagggcttcaaggcctctggagcagaagggaacaacatcgtaggacttctccgagat
gctatcaagaggagaggggactttgagatggatgtggtggcaatggtgaacgacacagtg
gccacaatgatctcctgctactatgaagaccgccaatgtgaggtcggcatgattgtgggc
actggctgcaatgcctgctacatggaggaaatgcagaatgtggagctggtggaaggggat
gagggacgcatgtgcgtcaacacggagtggggcgccttcggggactcgggcgagctggat
gagttcctactggagtatgaccggatggtggatgaaagctcagcgaaccccggtcagcag
ctgtacgagaagatcatcggtgggaagtatatgggcgagctggtacgacttgtgctgctt
aagctggtggacgagaaccttctgttccacggagaggcctcggagcagctgcgcacgcgt
ggtgcttttgagacccgtttcgtgtcacaagtggagagcgactccggggaccgaaagcag
atccacaacatcctaagcactctggggcttcgaccctctgtcaccgactgcgacattgtg
cgccgtgcctgtgaaagcgtgtccactcgcgccgcccatatgtgctccgcaggactagct
ggggtcataaatcgcatgcgcgaaagccgcagtgaggacgtgatgcgcatcactgtgggc
gtggatggctccgtgtacaagctgcacccgagcttcaaggagcggtttcacgccagtgtg
cgcaggctgacacccaactgcgaaatcaccttcatcgaatcagaggagggcagcggcagg
ggagccgcgctggtctctgcggtggcctgcaagaaggcttgcatgctggcccagtga

DBGET integrated database retrieval system