KEGG   Rattus norvegicus (rat): 24385Help
Entry
24385             CDS       T01003                                 

Gene name
Gck, GLUKA, RNGK2
Definition
glucokinase (EC:2.7.1.2)
Orthology
K12407  
glucokinase [EC:2.7.1.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
Glycolysis / Gluconeogenesis
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Butirosin and neomycin biosynthesis
Metabolic pathways
Carbon metabolism
Insulin signaling pathway
Insulin secretion
Prolactin signaling pathway
Type II diabetes mellitus
Maturity onset diabetes of the young
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:rno00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    24385 (Gck)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    24385 (Gck)
   00052 Galactose metabolism
    24385 (Gck)
   00500 Starch and sucrose metabolism
    24385 (Gck)
   00520 Amino sugar and nucleotide sugar metabolism
    24385 (Gck)
  Biosynthesis of other secondary metabolites
   00524 Butirosin and neomycin biosynthesis
    24385 (Gck)
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    24385 (Gck)
   04910 Insulin signaling pathway
    24385 (Gck)
   04917 Prolactin signaling pathway
    24385 (Gck)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    24385 (Gck)
   04950 Maturity onset diabetes of the young
    24385 (Gck)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     24385 (Gck)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
14q21
AA seq 498 aa AA seqDB search
MAMDTTRCGAQLLTLGTNKCTNACSLLCRAGTHNGHMNPRCRTEQAAATQLPTCRVQLLL
NYHVEGRADPGRVPAAGGRPEEGDEPDAEGDGPWPEAGDPRGEVGDFLSLDLGGTNFRVM
LVKVGEGEAGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLG
FTFSFPVRHEDLDKGILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTV
ATMISCYYEDRQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELD
EFLLEYDRMVDESSANPGQQLYEKIIGGKYMGELVRLVLLKLVDENLLFHGEASEQLRTR
GAFETRFVSQVESDSGDRKQIHNILSTLGLRPSVTDCDIVRRACESVSTRAAHMCSAGLA
GVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPNCEITFIESEEGSGR
GAALVSAVACKKACMLAQ
NT seq 1497 nt NT seq  +upstreamnt  +downstreamnt
atggctatggatactacaaggtgtggagcccagttgttgactctgggcaccaacaaatgc
acgaatgcatgctccctgctgtgcagagcgggtactcacaacgggcacatgaaccctcgc
tgccgaacagagcaggcggccgccacacagctgcccacctgcagagtccagctactcttg
aactatcatgtggagggtcgagcagatcctggcagagttccagctgcaggaggaagacct
gaagaaggtgatgagccggatgcagaaggagatggaccgtggcctgaggctggagaccca
cgaggagaagtcggagactttctctccttagacctgggaggaaccaacttcagagtgatg
ctggtcaaagtgggagagggggaggcagggcagtggagcgtgaagacaaaacaccagatg
tactccatccccgaggacgccatgacgggcactgccgagatgctctttgactacatctct
gaatgcatctctgacttccttgacaagcatcagatgaagcacaagaaactgcccctgggc
ttcaccttctccttccctgtgaggcacgaagacctagacaagggcatcctcctcaattgg
accaagggcttcaaggcctctggagcagaagggaacaacatcgtaggacttctccgagat
gctatcaagaggagaggggactttgagatggatgtggtggcaatggtgaacgacacagtg
gccacaatgatctcctgctactatgaagaccgccaatgtgaggtcggcatgattgtgggc
actggctgcaatgcctgctacatggaggaaatgcagaatgtggagctggtggaaggggat
gagggacgcatgtgcgtcaacacggagtggggcgccttcggggactcgggcgagctggat
gagttcctactggagtatgaccggatggtggatgaaagctcagcgaaccccggtcagcag
ctgtacgagaagatcatcggtgggaagtatatgggcgagctggtacgacttgtgctgctt
aagctggtggacgagaaccttctgttccacggagaggcctcggagcagctgcgcacgcgt
ggtgcttttgagacccgtttcgtgtcacaagtggagagcgactccggggaccgaaagcag
atccacaacatcctaagcactctggggcttcgaccctctgtcaccgactgcgacattgtg
cgccgtgcctgtgaaagcgtgtccactcgcgccgcccatatgtgctccgcaggactagct
ggggtcataaatcgcatgcgcgaaagccgcagtgaggacgtgatgcgcatcactgtgggc
gtggatggctccgtgtacaagctgcacccgagcttcaaggagcggtttcacgccagtgtg
cgcaggctgacacccaactgcgaaatcaccttcatcgaatcagaggagggcagcggcagg
ggagccgcgctggtctctgcggtggcctgcaagaaggcttgcatgctggcccagtga

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