KEGG   Rattus norvegicus (rat): 24681Help
Entry
24681             CDS       T01003                                 

Gene name
Prkcg, PKC, PKCI, Prkc, Prkcc, RATPKCI
Definition
(RefSeq) protein kinase C, gamma (EC:2.7.11.13)
  KO
K19663  
classical protein kinase C gamma type [EC:2.7.11.13]
Organism
rno  Rattus norvegicus (rat)
Pathway
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
Sphingolipid signaling pathway
mTOR signaling pathway
Vascular smooth muscle contraction
Wnt signaling pathway
VEGF signaling pathway
Focal adhesion
Tight junction
Gap junction
Natural killer cell mediated cytotoxicity
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Aldosterone synthesis and secretion
Aldosterone-regulated sodium reabsorption
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Amphetamine addiction
Morphine addiction
African trypanosomiasis
Amoebiasis
Hepatitis B
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    24681 (Prkcg)
   04015 Rap1 signaling pathway
    24681 (Prkcg)
   04010 MAPK signaling pathway
    24681 (Prkcg)
   04012 ErbB signaling pathway
    24681 (Prkcg)
   04310 Wnt signaling pathway
    24681 (Prkcg)
   04370 VEGF signaling pathway
    24681 (Prkcg)
   04066 HIF-1 signaling pathway
    24681 (Prkcg)
   04020 Calcium signaling pathway
    24681 (Prkcg)
   04070 Phosphatidylinositol signaling system
    24681 (Prkcg)
   04071 Sphingolipid signaling pathway
    24681 (Prkcg)
   04150 mTOR signaling pathway
    24681 (Prkcg)
 Cellular Processes
  Cellular commiunity
   04510 Focal adhesion
    24681 (Prkcg)
   04530 Tight junction
    24681 (Prkcg)
   04540 Gap junction
    24681 (Prkcg)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    24681 (Prkcg)
   04666 Fc gamma R-mediated phagocytosis
    24681 (Prkcg)
   04670 Leukocyte transendothelial migration
    24681 (Prkcg)
  Endocrine system
   04911 Insulin secretion
    24681 (Prkcg)
   04921 Oxytocin signaling pathway
    24681 (Prkcg)
   04918 Thyroid hormone synthesis
    24681 (Prkcg)
   04919 Thyroid hormone signaling pathway
    24681 (Prkcg)
   04916 Melanogenesis
    24681 (Prkcg)
   04925 Aldosterone synthesis and secretion
    24681 (Prkcg)
  Circulatory system
   04270 Vascular smooth muscle contraction
    24681 (Prkcg)
  Digestive system
   04970 Salivary secretion
    24681 (Prkcg)
   04971 Gastric acid secretion
    24681 (Prkcg)
   04972 Pancreatic secretion
    24681 (Prkcg)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    24681 (Prkcg)
   04961 Endocrine and other factor-regulated calcium reabsorption
    24681 (Prkcg)
  Nervous system
   04724 Glutamatergic synapse
    24681 (Prkcg)
   04727 GABAergic synapse
    24681 (Prkcg)
   04725 Cholinergic synapse
    24681 (Prkcg)
   04728 Dopaminergic synapse
    24681 (Prkcg)
   04726 Serotonergic synapse
    24681 (Prkcg)
   04720 Long-term potentiation
    24681 (Prkcg)
   04730 Long-term depression
    24681 (Prkcg)
   04723 Retrograde endocannabinoid signaling
    24681 (Prkcg)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    24681 (Prkcg)
  Environmental adaptation
   04713 Circadian entrainment
    24681 (Prkcg)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    24681 (Prkcg)
   05231 Choline metabolism in cancer
    24681 (Prkcg)
   05206 MicroRNAs in cancer
    24681 (Prkcg)
   05205 Proteoglycans in cancer
    24681 (Prkcg)
   05214 Glioma
    24681 (Prkcg)
   05223 Non-small cell lung cancer
    24681 (Prkcg)
  Substance dependence
   05031 Amphetamine addiction
    24681 (Prkcg)
   05032 Morphine addiction
    24681 (Prkcg)
  Infectious diseases
   05161 Hepatitis B
    24681 (Prkcg)
   05146 Amoebiasis
    24681 (Prkcg)
   05143 African trypanosomiasis
    24681 (Prkcg)
  Antineoplastic resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    24681 (Prkcg)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     24681 (Prkcg)
Protein kinases [BR:rno01001]
 Serine/threonine protein kinases: AGC group
  PKC family [OT]
   24681 (Prkcg)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
1q12
AA seq 697 aa AA seqDB search
MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG
KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL
LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTSDEIHITVGEA
RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWNETFVFNLKPGDVERRL
SVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQ
KFEACNYPLELYERVRMGPSSSPIPSPSPSPTDSKRCFFGASPGRLHISDFSFLMVLGKG
SFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQL
HSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRD
LKLDNVMLDAEGHIKITDFGMCKENVFPGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWS
FGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGS
GPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCGRSGENFDKFFTRAAPALTPPDRL
VLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM
NT seq 2094 nt NT seq  +upstreamnt  +downstreamnt
atggcgggtctgggtcctggcgggggcgactcagaagggggaccccgacccctgttttgc
agaaagggggcgctgaggcagaaggtggtccacgaggtgaagagccacaagttcaccgct
cgtttcttcaagcagccaaccttctgcagtcactgtaccgacttcatctggggcattgga
aagcagggcctgcaatgtcaagtctgcagctttgtggttcaccgccgatgccacgaattt
gtgaccttcgagtgtccaggagctggaaagggcccccagacggacgaccctcgcaacaag
cacaagttccgtctgcacagctacagcagtcccaccttctgcgaccactgtggttccctc
ctctacgggctggtgcaccagggcatgaaatgttcctgttgcgaaatgaatgtgcaccga
cgctgtgtgcgcagcgtgccctccctttgcggcgtggaccatacagagcgccgtggacgt
ctgcaactggaaatccgggctcccacatcagatgagatccatattactgtgggtgaggcc
cggaacctcattcctatggaccccaatggcctgtctgatccctatgtgaaactgaagctc
atcccggaccctcggaacctgacaaaacagaagacaaagaccgtgaaagccacactgaat
cccgtgtggaacgagaccttcgtgttcaacctgaagccgggggatgtggagcgccggctc
agtgtggaggtgtgggattgggataggacatcccgaaatgacttcatgggtgccatgtcc
tttggtgtctcagagctactcaaggctcctgtggatggatggtacaagttactgaaccag
gaggagggcgagtattacaatgtaccggtggccgatgctgacaactgcagcctcctccag
aagtttgaggcctgtaattaccccttggaattgtatgagagagtgcggatgggcccctct
tcctctcccattccttctccatcccccagtcccacggactccaagagatgcttcttcggt
gccagcccaggacgcctgcatatctctgacttcagcttcctcatggttctagggaaaggc
agttttgggaaggtgatgctggcagagcgcagaggatccgatgaactctatgccatcaag
atactgaaaaaagacgtcattgtccaggatgatgatgtagactgcacccttgtggagaag
cgtgtgctggcattgggaggccgaggtcctggaggccggccacactttctcacacaactt
cattccacctttcagactccggaccgcctgtattttgtgatggagtacgtcactgggggc
gatttaatgtaccacattcagcaactgggcaagtttaaggagccccacgcagcattctat
gccgcggaaatcgccataggcctcttcttccttcacaaccagggcatcatctacagggac
ctcaagttggataatgtgatgctggatgctgaaggacacatcaagatcacagacttcggc
atgtgtaaagagaatgtcttccctgggtccacaacccgcaccttctgtgggaccccagac
tacatagcacctgagatcattgcctatcagccctatgggaagtctgtcgactggtggtcc
tttggagtcctgctgtatgagatgttggcaggacagccaccctttgatggggaagatgag
gaggagctgtttcaagccatcatggaacaaactgtcacctatcccaagtcactttcccgg
gaagctgtggccatctgcaaggggttcctgaccaagcacccaggaaagcgcctgggctca
gggccagatggggaacccaccatccgggctcatggctttttccgttggatcgattgggag
aggttggagagactggaaattgcgcctccttttagaccacgtccgtgtggccgcagcggc
gaaaactttgacaagttcttcacgcgggcagcgccagccttgaccccgccagaccgcttg
gtcctagccagcatcgaccaagctgatttccagggctttacttatgtgaacccggacttc
gtgcacccagatgcccgcagccccacaagccctgtgcctgtgcccgtcatgtaa

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