KEGG   Rattus norvegicus (rat): 25267Help
Entry
25267             CDS       T01003                                 

Gene name
Pdgfra, APDGFR, PDGFACE
Definition
platelet derived growth factor receptor, alpha polypeptide (EC:2.7.10.1)
Orthology
K04363  
platelet-derived growth factor receptor alpha [EC:2.7.10.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
Cytokine-cytokine receptor interaction
Endocytosis
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Regulation of actin cytoskeleton
HTLV-I infection
Pathways in cancer
MicroRNAs in cancer
Glioma
Prostate cancer
Melanoma
Class
Environmental Information Processing; Signal transduction; Ras signaling pathway [PATH:rno04014]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:rno04015]
Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:rno04010]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:rno04020]
Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:rno04151]
Environmental Information Processing; Signaling molecules and interaction; Cytokine-cytokine receptor interaction [PATH:rno04060]
Cellular Processes; Transport and catabolism; Endocytosis [PATH:rno04144]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:rno04810]
Cellular Processes; Cell communication; Focal adhesion [PATH:rno04510]
Cellular Processes; Cell communication; Gap junction [PATH:rno04540]
Human Diseases; Cancers; Pathways in cancer [PATH:rno05200]
Human Diseases; Cancers; MicroRNAs in cancer [PATH:rno05206]
Human Diseases; Cancers; Glioma [PATH:rno05214]
Human Diseases; Cancers; Melanoma [PATH:rno05218]
Human Diseases; Cancers; Prostate cancer [PATH:rno05215]
Human Diseases; Infectious diseases; HTLV-I infection [PATH:rno05166]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
14p11
AA seq 1088 aa AA seqDB search
MGTSQAFLVLSCLLTGPSLIVCQLLLPSILPNENEKIVPLSSSFSLRCFGESEVSWQHPM
SEEEDPNVEIRTEENNSSLFVTVLEVVNASAAHTGWYTCYYNHTQTEESEIEGRHIYIYV
PDPDMAFVPLGMTDSLVIVEEDDSAIIPCRTTDPDTEVTLHNNGRLVPASYDSRQGFNGT
FSVGPYICEATVRGRTFKTSEFNVYALKATSELNLEMDTRQTVYKAGETIVVTCAVFNNE
VVDLQWTYPGEVRNKGITMLEEIKLPSIKLVYTLTVPKATVKDSGDYECAARQATKEVKE
MKTVTISVHEKGFVQIRPTFGHLETVNLHQVREFVVEVQAYPTPRISWLKDNLTLIENLT
EITTDVQRSQETRYQSKLKLIRAKEEDSGHYTIIVQNDDDMKSYTFELSTLVPASILELV
DDHHGSGGGQTVRCTAEGTPLPNIEWMICKDIKKCNNDTSWTVLASNVSNIITEFHQRGR
STVEGRVSFAKVEETIAVRCLAKNDLGIGNRELKLVAPTLRSELTVAAAVLVLLVIVIVS
LIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGS
GAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLL
GACTKSGPIYIITEYCFYGDLVNYLHKNRDSFMSRHPEKPKKDLDIFGLNPADESTRSYV
ILSFENNGDYVDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEAKNL
LSDDDSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLAR
DIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGVLLWEIFSLGGTPYPGMMV
DSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPGQYKKS
YEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKEWEGGLDEQRLSADSGYIIP
LPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSS
DLVEDSFL
NT seq 3267 nt NT seq  +upstreamnt  +downstreamnt
atggggacctcccaggcctttctggtcctcagctgtctcctcacagggccgagcctcatc
gtctgccagctcttattaccctccatccttccaaatgagaatgagaagattgtgccgctg
agttcgtccttctctctgagatgcttcggggagagcgaagtgagctggcagcaccccatg
tctgaagaagaggaccccaacgtggaaatcagaaccgaggagaacaacagtagcctcttt
gtcacggtgctggaagtggtcaacgcctcagcggcccacaccggatggtacacttgctat
tacaaccacactcagacagaagagagtgagatcgaaggcaggcacatttatatctatgta
ccagacccagacatggccttcgtgcctctcggcatgacggattctttagtcattgtggaa
gaggacgattctgccatcataccctgccgcaccacggatccagacactgaagtaaccttg
cacaataacgggaggctggtgcctgcctcctacgacagcaggcagggcttcaacggaacc
ttcagtgtggggccttacatctgtgaggccaccgtcagagggaggacgttcaagaccagc
gagtttaacgtttatgccttgaaagccacgtcagaactgaatctggagatggacacacgc
cagactgtgtataaggcaggagaaacgatcgtggtgacctgcgccgtctttaacaatgag
gtggttgacctgcagtggacttaccctggagaggtgagaaacaaaggcatcaccatgctg
gaggagatcaaactcccgtccatcaaactggtgtacacgctgaccgtccccaaggccacg
gtgaaggacagtggagattatgaatgtgctgcccgccaggccacgaaagaggtcaaggaa
atgaagacagtcaccatttctgttcacgagaaaggcttcgtccagatcaggcccaccttt
ggccatctggaaactgtgaacctgcatcaggtcagagagttcgtggtggaggtgcaggcc
tacccgacccccaggatatcctggctgaaggacaacttgaccctgattgagaatctcact
gagatcaccaccgatgtgcagaggagccaggagacgaggtatcaaagcaaattaaagctg
atccgggctaaggaagaagacagcggccattataccattatagttcagaatgacgacgac
atgaagagctacacgtttgagctgtcaactctagttcctgcctccattctggagcttgtg
gatgaccaccatggctctggcgggggacagactgtgaggtgcacggctgaaggcacccct
cttccgaacatcgagtggatgatctgcaaggatattaagaaatgtaataatgacacttca
tggacagttttggccagcaacgtctcgaatattatcacggagttccaccagcgaggcagg
agtacagtggagggacgagtgtccttcgccaaggtggaagagaccatcgcagttcggtgc
ttggcaaagaacgaccttggcattgggaacagagagctgaagctggtggctcccaccctg
cgatctgagctcacggtggcggccgcggtgctggtgctgttggtgattgtcattgtctct
ctcattgtcctggttgtcatttggaagcagaaaccacggtatgaaattcgatggagggtc
attgagtcaatcagccctgatggacatgagtatatttatgtggaccccatgcagctgcct
tacgactccagatgggagttcccgagagatggactagtgcttggtcggatcttgggatcc
ggtgcatttgggaaagtggttgaaggcacagcttatggattaagccggtcccagcctgta
atgaaggtggctgtgaagatgctcaaacccacagccaggtctagtgagaagcaagctctc
atgtctgagctgaagataatgactcacttgggaccgcatctgaacattgtgaatttgctg
ggagcctgcaccaagtcaggccccatttacatcatcacagaatactgcttctatggggat
ttggtcaattacctgcataagaacagagatagcttcatgagccgacacccagagaagcca
aagaaagacctggacatctttggattgaatcctgcagatgagagtaccaggagttacgtg
attttatcttttgaaaacaatggtgactacgtggacatgaagcaggctgacaccacacag
tacgtgccaatgctggaaaggaaggaggtttccaaatactccgacatccagagatcgctg
tacgatcggccggcctcctataagaagaaatccatgctagactcagaagctaaaaacctc
ctttcggatgatgactccgagggtctgactttgctggacctactaagcttcacctaccaa
gtggcccgagggatggaatttttggcttcgaaaaattgtgtccaccgggacctggctgcc
cgcaacgtccttctggcgcaggggaaaatcgtgaagatctgtgacttcgggctggccaga
gacatcatgcacgattctaactacgtgtcaaagggcagcactttcctgcctgtgaagtgg
atggcacctgagagcatttttgacaacctctacaccacgctgagtgacgtctggtcttat
ggcgttctgctctgggaaatattctcccttggtggcacaccctaccctggcatgatggtt
gattctactttctacaataagatcaagagcggatacaggatggccaaacccgaccatgcc
accagtgaagtctatgagattatggtgcagtgctggaacagtgaacccgaaaagagaccc
tccttctaccacctcagcgagatagtggagaatctgctgcctggacagtacaaaaagagt
tatgaaaagattcacctggacttcctaaagagtgaccatccggctgtggcacgcatgcgt
gtggactctgacaacgcgtacatcggtgtcacttacaaaaatgaagaggacaagctgaag
gaatgggaaggtggcctggatgaacagagattgagcgcagatagtggctacatcattccc
ctgccagacattgaccctgttccagaggaggaagacctgggcaagaggaacagacacagc
tcgcagacttcggaagagagcgccatcgagacgggttccagtagttccactttcatcaag
agagaggacgagaccattgaggacatcgacatgatggatgatattggcatagattcctca
gacctggtggaggacagcttcctgtaa

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