KEGG   Rattus norvegicus (rat): 25272Help
Entry
25272             CDS       R.norvegicus                           
Gene name Mapk10
Definition mitogen activated protein kinase 10 (EC:2.7.11.24)
Orthology K04440  c-Jun N-terminal kinase [EC:2.7.11.24]
Pathway rno04010  MAPK signaling pathway
rno04012  ErbB signaling pathway
rno04310  Wnt signaling pathway
rno04510  Focal adhesion
rno04620  Toll-like receptor signaling pathway
rno04621  NOD-like receptor signaling pathway
rno04622  RIG-I-like receptor signaling pathway
rno04664  Fc epsilon RI signaling pathway
rno04722  Neurotrophin signaling pathway
rno04910  Insulin signaling pathway
rno04912  GnRH signaling pathway
rno04914  Progesterone-mediated oocyte maturation
rno04920  Adipocytokine signaling pathway
rno04930  Type II diabetes mellitus
rno05200  Pathways in cancer
rno05210  Colorectal cancer
rno05212  Pancreatic cancer
Class Metabolism; Enzyme Families; Protein kinases
Environmental Information Processing; Signal Transduction; MAPK
signaling pathway [PATH:rno04010]
Environmental Information Processing; Signal Transduction; ErbB
signaling pathway [PATH:rno04012]
Environmental Information Processing; Signal Transduction; Wnt
signaling pathway [PATH:rno04310]
Cellular Processes; Cell Communication; Focal adhesion
[PATH:rno04510]
Organismal Systems; Immune System; Toll-like receptor signaling
pathway [PATH:rno04620]
Organismal Systems; Immune System; NOD-like receptor signaling
pathway [PATH:rno04621]
Organismal Systems; Immune System; RIG-I-like receptor signaling
pathway [PATH:rno04622]
Organismal Systems; Immune System; Fc epsilon RI signaling pathway
[PATH:rno04664]
Organismal Systems; Endocrine System; Insulin signaling pathway
[PATH:rno04910]
Organismal Systems; Endocrine System; Adipocytokine signaling
pathway [PATH:rno04920]
Organismal Systems; Endocrine System; GnRH signaling pathway
[PATH:rno04912]
Organismal Systems; Endocrine System; Progesterone-mediated oocyte
maturation [PATH:rno04914]
Organismal Systems; Nervous System; Neurotrophin signaling pathway
[PATH:rno04722]
Human Diseases; Cancers; Pathways in cancer [PATH:rno05200]
Human Diseases; Cancers; Colorectal cancer [PATH:rno05210]
Human Diseases; Cancers; Pancreatic cancer [PATH:rno05212]
Human Diseases; Metabolic Diseases; Type II diabetes mellitus
[PATH:rno04930]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: Pkinase Pkinase_Tyr Kdo RIO1 APH
PROSITE: MAPK PROTEIN_KINASE_ST PROTEIN_KINASE_DOM
Motif
Other DBs NCBI-GI: 6981528
NCBI-GeneID: 25272
RGD: 3663
RATMAP: ENSRNOG00000002079
Ensembl: ENSRNOG00000002079
UniProt: P49187
Position 14p22
AA seq 426 aa AA seqDB search
MSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ
MELDHERMSYLLYQMLSAIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQ
LGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSK
MLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEV
MNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAG
PLGCCR
NT seq 1281 nt NT seq  +upstreamnt  +downstreamnt
atgagcaaaagcaaggtagataaccagttctacagtgtggaagtgggagactcaaccttc
acagttctaaagcgctaccagaacctgaagccgatcggctctggggctcagggaatagtt
tgtgctgcgtatgacgctgtcctcgacagaaatgtggccattaagaagctcagcagaccc
ttccagaaccaaactcatgccaagagggcttaccgggagctggtcctcatgaagtgtgtg
aaccataaaaacattattagcttattaaatgtctttacaccccagaaaacactggaggag
ttccaagatgtttacttagtgatggaactgatggacgccaacttgtgtcaggtgattcag
atggagctggaccacgagcggatgtcgtacttgctgtaccagatgctgtcggcgatcaaa
cacctccactccgctgggatcatccacagggacttaaaacccagtaacatcgtagtcaag
tctgattgcacactgaaaatcctggactttggactggccaggacagcgggcacaagcttc
atgatgactccgtatgtggtgacgagatattacagagcccccgaggtcatcctgggcatg
ggctacaaggagaacgtggacatatggtctgtgggctgcatcatgggagaaatggttcgt
cacaaaatcctctttcccggaagggactatattgaccagtggaacaaagtcatagagcag
ctaggaactccgtgtccagaattcatgaagaaattgcagcccaccgtcagaaactacgtg
gagaaccggcccaagtatgcaggcctcaccttccccaagctctttccagattccctcttc
ccagcggattccgagcacaataaacttaaagccagccaagccagggacttgttgtcaaag
atgttagtgattgacccagcgaagaggatatcggtggatgacgcattgcagcatccgtac
atcaacgtttggtacgaccctgctgaagtggaggcgcctccgcctcagatatatgacaag
caattggatgaaagggagcacaccatcgaagaatggaaagaactcatctacaaggaagta
atgaactcagaagagaagactaagaacggcgtagtcaaaggccagccctcaccttcaggt
gcagcagtgaacagcagtgagagtctccctccatcctcatctgtcaacgacatctcctcc
atgtccaccgaccagaccctcgcatccgacactgacagcagcctggaagcctcggcggga
ccgctgggttgttgcaggtga
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