KEGG   Rattus norvegicus (rat): 25272Help
Entry
25272             CDS       T01003                                 

Gene name
Mapk10, Jnk3, SAPKC, SAPb, Serk2
Definition
(RefSeq) mitogen activated protein kinase 10 (EC:2.7.11.24)
  KO
K04440  
c-Jun N-terminal kinase [EC:2.7.11.24]
Organism
rno  Rattus norvegicus (rat)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
cAMP signaling pathway
FoxO signaling pathway
Sphingolipid signaling pathway
Protein processing in endoplasmic reticulum
Apoptosis
Apoptosis - multiple species
Wnt signaling pathway
Osteoclast differentiation
Focal adhesion
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Adipocytokine signaling pathway
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
AGE-RAGE signaling pathway in diabetic complications
Salmonella infection
Pertussis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Hepatitis B
Influenza A
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Colorectal cancer
Pancreatic cancer
Choline metabolism in cancer
Module
MAPK (JNK) signaling
Brite
KEGG Orthology (KO) [BR:rno00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    25272 (Mapk10)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    25272 (Mapk10)
   04010 MAPK signaling pathway
    25272 (Mapk10)
   04012 ErbB signaling pathway
    25272 (Mapk10)
   04310 Wnt signaling pathway
    25272 (Mapk10)
   04668 TNF signaling pathway
    25272 (Mapk10)
   04068 FoxO signaling pathway
    25272 (Mapk10)
   04071 Sphingolipid signaling pathway
    25272 (Mapk10)
   04024 cAMP signaling pathway
    25272 (Mapk10)
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    25272 (Mapk10)
   04215 Apoptosis - multiple species
    25272 (Mapk10)
  Cellular commiunity
   04510 Focal adhesion
    25272 (Mapk10)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    25272 (Mapk10)
   04621 NOD-like receptor signaling pathway
    25272 (Mapk10)
   04622 RIG-I-like receptor signaling pathway
    25272 (Mapk10)
   04664 Fc epsilon RI signaling pathway
    25272 (Mapk10)
  Endocrine system
   04910 Insulin signaling pathway
    25272 (Mapk10)
   04920 Adipocytokine signaling pathway
    25272 (Mapk10)
   04912 GnRH signaling pathway
    25272 (Mapk10)
   04914 Progesterone-mediated oocyte maturation
    25272 (Mapk10)
   04917 Prolactin signaling pathway
    25272 (Mapk10)
  Nervous system
   04728 Dopaminergic synapse
    25272 (Mapk10)
   04723 Retrograde endocannabinoid signaling
    25272 (Mapk10)
   04722 Neurotrophin signaling pathway
    25272 (Mapk10)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    25272 (Mapk10)
  Development
   04380 Osteoclast differentiation
    25272 (Mapk10)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    25272 (Mapk10)
   05231 Choline metabolism in cancer
    25272 (Mapk10)
   05210 Colorectal cancer
    25272 (Mapk10)
   05212 Pancreatic cancer
    25272 (Mapk10)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    25272 (Mapk10)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    25272 (Mapk10)
   04931 Insulin resistance
    25272 (Mapk10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    25272 (Mapk10)
  Infectious diseases
   05132 Salmonella infection
    25272 (Mapk10)
   05133 Pertussis
    25272 (Mapk10)
   05152 Tuberculosis
    25272 (Mapk10)
   05164 Influenza A
    25272 (Mapk10)
   05161 Hepatitis B
    25272 (Mapk10)
   05160 Hepatitis C
    25272 (Mapk10)
   05168 Herpes simplex infection
    25272 (Mapk10)
   05169 Epstein-Barr virus infection
    25272 (Mapk10)
   05145 Toxoplasmosis
    25272 (Mapk10)
   05142 Chagas disease (American trypanosomiasis)
    25272 (Mapk10)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     25272 (Mapk10)
Protein kinases [BR:rno01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   25272 (Mapk10)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
RGD: 
Ensembl: 
Vega: 
UniProt: 
Position
14p22
AA seq 426 aa AA seqDB search
MSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQ
LGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSK
MLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEV
MNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAG
PLGCCR
NT seq 1281 nt NT seq  +upstreamnt  +downstreamnt
atgagcaaaagcaaggtagataaccagttctacagtgtggaagtgggagactcaaccttc
acagttctaaagcgctaccagaacctgaagccgatcggctctggggctcagggaatagtt
tgtgctgcgtatgacgctgtcctcgacagaaatgtggccattaagaagctcagcagaccc
ttccagaaccaaactcatgccaagagggcttaccgggagctggtcctcatgaagtgtgtg
aaccataaaaacattattagcttattaaatgtctttacaccccagaaaacactggaggag
ttccaagatgtttacttagtgatggaactgatggacgccaacttgtgtcaggtgattcag
atggagctggaccacgagcggatgtcgtacttgctgtaccagatgctgtgcggcatcaaa
cacctccactccgctgggatcatccacagggacttaaaacccagtaacatcgtagtcaag
tctgattgcacactgaaaatcctggactttggactggccaggacagcgggcacaagcttc
atgatgactccgtatgtggtgacgagatattacagagcccccgaggtcatcctgggcatg
ggctacaaggagaacgtggacatatggtctgtgggctgcatcatgggagaaatggttcgt
cacaaaatcctctttcccggaagggactatattgaccagtggaacaaagtcatagagcag
ctaggaactccgtgtccagaattcatgaagaaattgcagcccaccgtcagaaactacgtg
gagaaccggcccaagtatgcaggcctcaccttccccaagctctttccagattccctcttc
ccagcggattccgagcacaataaacttaaagccagccaagccagggacttgttgtcaaag
atgttagtgattgacccagcgaagaggatatcggtggatgacgcattgcagcatccgtac
atcaacgtttggtacgaccctgctgaagtggaggcgcctccgcctcagatatatgacaag
caactggatgaaagggagcacaccatcgaagaatggaaagaactcatctacaaggaagta
atgaactcagaagagaagactaagaacggcgtagtcaaaggccagccctcaccttcaggt
gcagcagtgaacagcagtgagagtctccctccatcctcgtctgtcaacgacatctcctcc
atgtccaccgaccagaccctcgcatccgacactgacagcagcctggaagcctcggcggga
ccgctgggttgttgcaggtga

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