KEGG   Rattus norvegicus (rat): 25289Help
Entry
25289             CDS       T01003                                 

Gene name
Adcy6, AC6, ACVI, ADCYB
Definition
(RefSeq) adenylate cyclase 6 (EC:4.6.1.1)
  KO
K08046  
adenylate cyclase 6 [EC:4.6.1.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
Purine metabolism
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Phospholipase D signaling pathway
Oocyte meiosis
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Gap junction
Platelet activation
Circadian entrainment
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Regulation of lipolysis in adipocytes
Renin secretion
Aldosterone synthesis and secretion
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
HTLV-I infection
Pathways in cancer
Dilated cardiomyopathy
Module
cAMP signaling
Brite
KEGG Orthology (KO) [BR:rno00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    25289 (Adcy6)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    25289 (Adcy6)
   04072 Phospholipase D signaling pathway
    25289 (Adcy6)
   04024 cAMP signaling pathway
    25289 (Adcy6)
   04022 cGMP - PKG signaling pathway
    25289 (Adcy6)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    25289 (Adcy6)
  Cellular commiunity
   04540 Gap junction
    25289 (Adcy6)
 Organismal Systems
  Immune system
   04611 Platelet activation
    25289 (Adcy6)
   04062 Chemokine signaling pathway
    25289 (Adcy6)
  Endocrine system
   04911 Insulin secretion
    25289 (Adcy6)
   04923 Regulation of lipolysis in adipocyte
    25289 (Adcy6)
   04912 GnRH signaling pathway
    25289 (Adcy6)
   04913 Ovarian Steroidogenesis
    25289 (Adcy6)
   04915 Estrogen signaling pathway
    25289 (Adcy6)
   04914 Progesterone-mediated oocyte maturation
    25289 (Adcy6)
   04921 Oxytocin signaling pathway
    25289 (Adcy6)
   04918 Thyroid hormone synthesis
    25289 (Adcy6)
   04916 Melanogenesis
    25289 (Adcy6)
   04924 Renin secretion
    25289 (Adcy6)
   04925 Aldosterone synthesis and secretion
    25289 (Adcy6)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    25289 (Adcy6)
   04270 Vascular smooth muscle contraction
    25289 (Adcy6)
  Digestive system
   04970 Salivary secretion
    25289 (Adcy6)
   04971 Gastric acid secretion
    25289 (Adcy6)
   04972 Pancreatic secretion
    25289 (Adcy6)
   04976 Bile secretion
    25289 (Adcy6)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    25289 (Adcy6)
   04961 Endocrine and other factor-regulated calcium reabsorption
    25289 (Adcy6)
  Nervous system
   04724 Glutamatergic synapse
    25289 (Adcy6)
   04727 GABAergic synapse
    25289 (Adcy6)
   04725 Cholinergic synapse
    25289 (Adcy6)
   04723 Retrograde endocannabinoid signaling
    25289 (Adcy6)
  Sensory system
   04742 Taste transduction
    25289 (Adcy6)
   04750 Inflammatory mediator regulation of TRP channels
    25289 (Adcy6)
  Aging
   04211 Longevity regulating pathway - mammal
    25289 (Adcy6)
   04213 Longevity regulating pathway - multiple species
    25289 (Adcy6)
  Environmental adaptation
   04713 Circadian entrainment
    25289 (Adcy6)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    25289 (Adcy6)
  Substance dependence
   05032 Morphine addiction
    25289 (Adcy6)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    25289 (Adcy6)
  Infectious diseases
   05166 HTLV-I infection
    25289 (Adcy6)
Enzymes [BR:rno01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     25289 (Adcy6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
7
AA seq 1166 aa AA seqDB search
MSWFSGLLVPKVDERKTAWGERNGQKRPRQATRARGFCAPRYMSCLKNVEPPSPTPAART
RCPWQDEAFIRRAGPGRGVKLGLRSVALGFDDTEVTTPMGTAEVAPDTSPRSGPSCWHRL
AQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLMAVLLTFHAAPALPQPAYVA
LLTCASVLFVVLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPRSPSAGLWCP
VFFVYITYTLLPIRMRAAVLSGLGLSTLHLILAWHLNNGDPFLWKQLGANVVLFLCTNAI
GVCTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKK
EDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLR
IKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHC
GVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNGYL
KEQCIETFLILGASQKRKEEKAMLVKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFRQM
GIDDSSKENRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYS
RKVDPRFGAYVACALLVFCFICFIQFLVFPHSALILGIYAGIFLLLLVTVLICAVCSCGS
FFPNALQRLSRSIVRSRVHSTAVGVFSVLLVFISAIANMFTCSHTPLRTCAARMLNLTPS
DVTACHLRQINYSLGLEAPLCEGTAPTCSFPEYFVGSVLLSLLASSVFLHISSIGKLVMT
FVLGFIYLLLLLLGPPATIFDNYDLLLSVHGLASSNETFDGLDCPAVGRVALKYMTPVIL
LVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLA
RERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEE
RFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQ
MKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQ
LECRGVVKVKGKGEMTTYFLNGGPSS
NT seq 3501 nt NT seq  +upstreamnt  +downstreamnt
atgtcatggtttagcggcctcctggttcccaaagtggatgaacggaaaacagcctggggc
gaacgcaatggacagaagcgcccacgccaggcgacccgagcccgtggcttctgcgcgccc
cgctacatgagctgcctcaagaatgtggagccacccagccccactcctgcagctcgcact
cggtgcccctggcaggatgaagccttcatcaggagggctggcccgggaaggggtgtgaag
ctggggctgcggtcagtggccttgggttttgatgacactgaggtgaccacaccgatgggg
acagctgaagtggcacccgacacatcgcctcgaagcggtccgtcctgctggcaccggcta
gcgcaggtgttccagtctaagcagttccgctccgccaagctggagcgtctgtaccagcgg
tacttcttccagatgaaccagagcagcctcacgctgctcatggcggtgcttgtgctcctc
atggctgtactgttgaccttccacgccgcgcctgccctgcctcagcctgcttatgtggcc
ctgctgacctgtgcctccgtcctttttgtggtactcatggtagtgtgtaaccgacatagc
ttccgccaggactccatgtgggtagtgagctatgtggttctgggcatcctagcagccgtg
caagtcgggggtgccctggcagccaacccacgcagcccctcagcaggcctttggtgcccc
gtgttcttcgtctacatcacctacacacttcttcccattcgtatgcgagcggccgtgctc
agtggcctgggtctttccaccctgcatttgattttggcctggcatctcaacaatggtgac
cccttcctttggaagcagctcggtgctaacgtggtgctcttcctgtgcaccaatgccatc
ggtgtctgcacgcactaccccgctgaagtgtctcagcgccaagcctttcaggagacccgt
ggttacatccaggcccggctgcacttgcagcatgagaatcgacagcaggaacggctgctg
ctgtcggtgttgccccagcatgttgccatggaaatgaaagaggatatcaacacaaaaaag
gaagacatgatgttccacaagatttacatccagaagcatgacaatgtcagcatcctgttt
gccgacatcgagggcttcaccagcctggcctcccagtgcactgcccaggaactggtcatg
accttgaatgagctctttgcccggttcgacaagctggctgcggagaatcactgtctgagg
atcaagatcttaggagactgttactactgtgtgtcggggctgccggaggcccgggcagac
catgcccactgctgtgtggagatgggggtagacatgatcgaggccatctcgctggtgcgt
gaggtaacgggtgtaaatgtgaacatgcgcgtgggcatccacagcgggcgtgtacactgc
ggtgtccttggtctgcggaaatggcagtttgatgtctggtccaacgatgtgaccctggcc
aaccacatggaggcggggggccgggccggccgcatccacatcactcgggccacactgcag
tacctgaacggggactatgaggtggagccaggccgtggcggtgagcgcaacggctacctc
aaggagcagtgcattgagaccttcctcatactaggagccagccagaaacggaaagaggag
aaggccatgctggtcaagctgcagcggacgcgggccaactccatggaaggactgatgccc
cgctgggttcctgaccgtgccttctcccggaccaaggactctaaggcattccgacagatg
ggcatcgatgactctagcaaagagaaccggggtgcccaagatgctctgaaccctgaggat
gaggtggacgagtttctgggccgagccatcgatgcccgaagcatcgaccagctgcgtaag
gaccatgtgcgccggttcctgctcaccttccagagggaggatctcgagaagaagtattca
cggaaagtagaccctcgtttcggagcctacgtcgcctgtgccctcctggttttctgcttc
atctgtttcatccagttcctcgtattcccacactccgccctgatactcgggatttatgcc
gggatcttccttttgctgctggtcaccgtgctcatctgtgctgtgtgctcctgtgggtct
ttcttccccaacgccctgcagcgcctgtcccgcagtatcgtccgctcacgggtgcacagc
acggctgttggagtcttctcggttctgcttgtgttcatctctgccattgccaacatgttc
acctgcagtcacaccccactgaggacctgtgcggcccggatgctgaacttaacaccgtcc
gatgtcaccgcctgtcacctacgacagatcaattactctctgggactggaagctcccctg
tgtgagggcacagcacccacctgcagtttccctgagtactttgtcgggagtgtgctgttg
agtctcttggccagctccgtcttcctccacatcagcagcattggcaagctagttatgacc
tttgtcttggggttcatctacttgcttctgcttttgctgggtcccccagccaccatcttt
gacaactatgatctactgcttagcgtccatggcttggcttcctccaatgagaccttcgat
gggctggactgcccagccgtagggagggtagcgctcaaatacatgacccctgtgattctc
ctcgtgttcgccctggcactgtatctacacgcacaacaggtggaatctaccgcccgcctg
gacttcctgtggaaactgcaggccacaggggagaaggaggagatggaggagttgcaggcc
tacaaccggcggctgctgcataacatccttcccaaggacgtggctgcccacttcctggcc
cgggagcgccgcaacgacgagctgtactaccaatcctgcgagtgcgtggctgtcatgttt
gcctccatcgccaacttctctgagttctatgtggaactggaggcgaacaatgagggcgtg
gagtgcctgcgactgctcaatgagatcatcgcggactttgatgagatcatcagtgaggag
aggttccggcagctggagaagatcaagaccatcggtagcacttacatggccgcctccggg
ctaaatgccagcacctatgaccaggtcggccgctcgcacatcaccgccctggcagactac
gccatgcggcttatggagcaaatgaaacacatcaacgaacactctttcaacaacttccag
atgaagatcgggttgaacatgggtccggttgtagcaggtgtcattggggcccggaagcca
cagtatgacatctggggaaacacggtgaatgtttccagccgtatggacagcacaggagtt
cctgaccgaatacaggtgaccacggatctctaccaggttctagctgccaagggctaccaa
ctggagtgtcgaggggtggtcaaggtgaagggaaagggggagatgaccacctacttcctc
aatgggggccccagcagttag

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