KEGG   Rattus norvegicus (rat): 25579Help
Entry
25579             CDS       T01003                                 

Gene name
Map3k12, DLK, MUK, PK, Zpk
Definition
mitogen activated protein kinase kinase kinase 12 (EC:2.7.11.25)
Orthology
K04423  
mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
Organism
rno  Rattus norvegicus (rat)
Pathway
MAPK signaling pathway
Module
MAPK (JNK) signaling
MAPK (p38) signaling
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    25579 (Map3k12)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     25579 (Map3k12)
Protein kinases [BR:rno01001]
 Serine/threonine protein kinases: TKL group
  MLK family
   25579 (Map3k12)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
7q36
AA seq 888 aa AA seqDB search
MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTQCVLRDVVPLGGQGG
GGPSPSPGGEPPPEPFANSVLQLHEQDTGGPGGATGSPESRASRVRADEVRLQCQSGSGF
LEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGE
EVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRP
VTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTK
MSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSL
HLPVPSSCPDGFKILLRQCWNRKPRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWR
EEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANNLYMELNALM
LQLELKERELLRREQALERRCPGLLKSHTSRSLLHGNTMEKLIKKRNVPQKLSPHSKRPD
ILKTESLLPKLDAALSGVGLPGCPKAPPSPGRSRRGKTRHRKASAKGSCGDLPGLRAALP
PHEPGGLGSPGGLGVGPTAWDASPPALRGLHHDLLLRKMSSSSPDLLSAALGARGRGATG
GARDPGSPPPPQGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGVGLLGTGREGTTG
RGGSRAGYQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELPPSQRWPQGPNMRQS
LSTFSSENPSDVEEGTASEPSPSGTPEVGSTNTDERPDERSDDMCSQGSEIPLDLPTSEV
VPERETSSLPMQHQDDQGPNPEDSDCDSTELDNSNSIDALPPPASLPP
NT seq 2667 nt NT seq  +upstreamnt  +downstreamnt
atggcctgcctccatgaaacccgaacaccctccccttcctttggaggctttgtgtctact
ctaagtgaggcctccatgcgaaagctggatccagacacttcagactgcacccctgagaag
gacctgacacctacccaatgtgtacttcgagatgttgtgcctctcggtgggcagggtgga
ggagggcccagcccctccccaggtggagagcctcctccagagccttttgccaatagtgtc
ctgcagctacatgagcaggatacaggtgggccagggggagccaccgggtcacctgagagt
cgagcatctagggttcgagctgatgaggtacgtctgcagtgccagagtggcagtggcttc
cttgaaggtctttttggctgcctgcgccctgtctggacaatgattggcaaagcctactcc
acagagcacaagcaacagcaggaagacctttgggaagtcccctttgaggaaatcctggac
ctgcagtgggtaggctcaggggctcagggtgccgttttcctgggacgctttcatggggag
gaggtagctgtgaagaaggttcgagacctcaaggagaccgacatcaagcatcttcgaaaa
ctgaagcaccccaacatcatcactttcaagggtgtttgcacacaggccccgtgctactgc
atcctcatggagttctgtgcccaaggacagctgtatgaggtgctcagggcgggccgcccc
gttaccccctccttgctggttgactggtccatgggcatcgctggaggcatgaattaccta
cacctgcacaaaatcatccacagagacctgaagtcacccaacatgctaatcacatacgac
gatgtggtgaagatctcagactttggcacttccaaggagctgagtgacaagagcaccaag
atgtcctttgcagggacagtagcctggatggctcctgaagtgatcagaaatgaacctgtg
tctgagaaggttgacatctggtcctttggggtggtgctttgggaattactgactggagag
attccctacaaagatgtagactcctcagccatcatctggggtgtgggaagcaacagtctt
cacctgcctgtaccctctagctgcccagacggctttaaaattctgcttcgccagtgctgg
aacagaaaacctcggaaccgcccatcattccgacagatcttgctgcacctggacatcgcc
tcggctgatgtgctctctacaccccaggagacttactttaaatcccaggcagagtggcgg
gaagaagtaaaactgcactttgaaaagattaagtcagaagggacctgtctgcaccgccta
gaagaggaactggtgatgcggagaagggaggagctcagacatgccctggacatcagggag
cactatgagcgcaagttggagagagctaacaacttgtacatggaactgaatgccctcatg
ttgcaactagaactcaaagagagggaattgctcaggcgagagcaagctttagaaaggagg
tgtcctggtctactgaagtcacacacgtcccgaagcctcctacatggaaacacgatggag
aagctcatcaagaaaaggaatgtgccacagaaactgtcaccccatagcaaaaggccagat
attctcaagacagagtctttgctacctaaactagatgcagccctaagtggggtggggctt
cctggttgtcctaaggcccccccttcacctgggaggagtcgtcgtggcaagacccgtcac
cgaaaggccagcgccaagggcagctgtggagacctgcctgggcttcgtgcagctttgcca
ccccatgagcctggaggactaggaagcccaggaggcctaggagtgggccctacagcttgg
gatgcctccccccctgctctccgtggactccaccatgaccttctacttcggaagatgtct
tcatcatccccagacctgttatcagcagcactgggagcccgaggccgaggggcaacaggg
ggagctcgggatcctggctcaccacctccaccccagggtgatactcctccaagtgaggga
tcagctcctggttccaccagcccagattcacctgggggagctaaaggggaaccacctcca
ccagtagggcctggagaaggtgtggggctgctgggaactggaagggaagggactacaggc
cggggaggaagccgggctgggtaccagcacttgacccccgctgcgctgctgtacagggct
gctgtgactcgtagtcagaaacgtggtatctcatctgaagaggaagaaggagaggtcgac
agtgaagtagagctacccccaagtcaaaggtggcctcagggcccgaacatgcgtcagtca
ctatctacgttcagctcagagaacccatcagatgtggaggaaggtacagctagtgagcct
tccccaagtggcacaccggaagttggcagcaccaacactgatgagcgaccagatgaacgg
tctgatgacatgtgctcacagggttcagaaatcccactggacctacctacttcagaggtg
gtccctgaacgtgaaaccagctccttgcccatgcaacaccaggatgaccagggccccaat
cctgaggactcagactgtgacagcactgaattggacaactccaacagcattgatgccttg
ccgcccccagcctcccttcctccatga

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