KEGG   Rattus norvegicus (rat): 25594Help
Entry
25594             CDS       T01003                                 

Gene name
Ppp1cb
Definition
protein phosphatase 1, catalytic subunit, beta isozyme (EC:3.1.3.16 3.1.3.53)
Orthology
K06269  
serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
rno  Rattus norvegicus (rat)
Pathway
mRNA surveillance pathway
cGMP-PKG signaling pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Hippo signaling pathway
Focal adhesion
Platelet activation
Long-term potentiation
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Oxytocin signaling pathway
Amphetamine addiction
Alcoholism
Herpes simplex infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 Genetic Information Processing
  Translation
   03015 mRNA surveillance pathway
    25594 (Ppp1cb)
 Environmental Information Processing
  Signal transduction
   04390 Hippo signaling pathway
    25594 (Ppp1cb)
   04022 cGMP - PKG signaling pathway
    25594 (Ppp1cb)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    25594 (Ppp1cb)
  Cell growth and death
   04114 Oocyte meiosis
    25594 (Ppp1cb)
  Cell communication
   04510 Focal adhesion
    25594 (Ppp1cb)
 Organismal Systems
  Immune system
   04611 Platelet activation
    25594 (Ppp1cb)
  Endocrine system
   04910 Insulin signaling pathway
    25594 (Ppp1cb)
   04921 Oxytocin signaling pathway
    25594 (Ppp1cb)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    25594 (Ppp1cb)
   04270 Vascular smooth muscle contraction
    25594 (Ppp1cb)
  Nervous system
   04728 Dopaminergic synapse
    25594 (Ppp1cb)
   04720 Long-term potentiation
    25594 (Ppp1cb)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    25594 (Ppp1cb)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    25594 (Ppp1cb)
  Substance dependence
   05031 Amphetamine addiction
    25594 (Ppp1cb)
   05034 Alcoholism
    25594 (Ppp1cb)
  Infectious diseases
   05168 Herpes simplex infection
    25594 (Ppp1cb)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     25594 (Ppp1cb)
Protein phosphatases and associated proteins [BR:rno01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     25594 (Ppp1cb)
Transcription machinery [BR:rno03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     25594 (Ppp1cb)
Spliceosome [BR:rno03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    25594 (Ppp1cb)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
6q13
AA seq 327 aa AA seqDB search
MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI
CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ
SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL
DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK
KAKYQYGGLNSGRPVTPPRTANPPKKR
NT seq 984 nt NT seq  +upstreamnt  +downstreamnt
atggcggacggggagctgaacgtggacagcctcatcacccgcctgctggaggtacgagga
tgtcgtccgggaaaaattgtgcagatgactgaagcagaagtccgaggactgtgtatcaag
tctcgtgaaatctttcttagccagcctattcttttggaattggaagcgccactgaagatt
tgtggagatattcatggacagtatacagacttactgagattatttgaatatggaggtttt
ccaccagaagccaactatcttttcttaggagattatgtggacagaggaaagcagtctttg
gaaaccatctgtttgctattggcttacaaaatcaaatacccagagaacttctttcttcta
cgaggaaaccatgagtgtgctagcatcaaccgcatttatggattctatgatgagtgcaaa
cgaagatttaatattaaattgtggaagacattcactgattgttttaattgtctgcctata
gctgctattgttgatgagaaaatcttctgctgtcatggaggactgtcaccagacctacag
tctatggaacagattcggagaattatgagacccactgacgtacctgatacaggtttgctt
tgtgatttactgtggtccgacccagataaggatgtacaaggctggggagaaaatgatcgt
ggtgtttcttttacttttggagctgatgtagtcagtaaatttctgaatcgtcatgatttg
gacttgatttgtcgagcccatcaggtggtagaagatggatatgaattttttgctaaacga
caattggtaactttattttctgccccaaattactgcggcgagtttgacaatgctggtggt
atgatgagtgtggatgaaactttgatgtgttcattccagatattgaaaccatctgaaaag
aaagctaagtaccagtatggtgggctgaattctggacgtcctgtcactccgcctcgaaca
gctaatccaccgaagaaaaggtga

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