KEGG   Rattus norvegicus (rat): 25692Help
Entry
25692             CDS       T01003                                 

Gene name
Plat, PATISS, tPA
Definition
(RefSeq) plasminogen activator, tissue type (EC:3.4.21.68)
  KO
K01343  
tissue plasminogen activator [EC:3.4.21.68]
Organism
rno  Rattus norvegicus (rat)
Pathway
Complement and coagulation cascades
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 Organismal Systems
  Immune system
   04610 Complement and coagulation cascades
    25692 (Plat)
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    25692 (Plat)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.68  t-plasminogen activator
     25692 (Plat)
Peptidases [BR:rno01002]
 Serine Peptidases
  Family S1: chymotrypsin family
   25692 (Plat)
Glycosaminoglycan binding proteins [BR:rno00536]
 Heparan sulfate/Haparin
  Coagulation and fibrinolysis (General comment) Coagulation, inflammation, complement control
   25692 (Plat)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
16q12.5
AA seq 559 aa AA seqDB search
MKGELLCVLLLCGVAFTLPDQGIHRRFRRGARSYRATCRDEQTQTTYQQHQSWLRPMLRG
NRVEYCRCNSGLAQCHSVPVRSCSEPRCFNGGTCQQALYFSDFVCQCPDGFVGKRCDIDT
RATCFEGQGITYRGTWSTAENGAECINWNSSALSQKPYSARRPNAIKLGLGNHNYCRNPD
RDVKPWCYVFKAGKYTTEFCSTPACPKGPTEDCYVGKGVTYRGTHSFTTSKASCLPWNSM
ILIGKTYTAWRANSQALGLGRHNYCRNPDGDAKPWCHVMKDRKLTWEYCDMSPCSTCGLR
QYKQPQFRIKGGLFTDITSHPWQAAIFVKNKRSPGERFLCGGVLISSCWVLSAAHCFVER
FPPHHLKVVLGRTYRVVPGEEEQTFEIEKYIVHKEFDDDTYDNDIALLQLRSDSSQCAQE
SSSVGTACLPDPDVQLPDWTECELSGYGKHEASSPFFSDRLKEAHVRLYPSSRCTSQHLF
NKTITSNMLCAGDTRTGGNQDVHDACQGDSGGPLVCMIDKRMTLLGIISWGLGCGQKDVP
GIYTKVTNYLNWIQDNMKQ
NT seq 1680 nt NT seq  +upstreamnt  +downstreamnt
atgaagggagagctgttgtgcgtcctgctgctttgtggagtggcgttcacgttgcctgac
cagggaatacacaggaggttcagaagaggagctcggtcctacagagcgacctgcagagat
gaacagactcagacaacttaccaacagcatcagtcatggctacgtcccatgctcagaggc
aatcgggtggaatactgccggtgcaacagcggcctggcacagtgccactcggtgcccgtc
cgaagttgcagtgaaccgagatgcttcaatgggggtacgtgtcagcaggccctgtatttc
tctgacttcgtctgccagtgccctgacggatttgttgggaaacgctgtgatatagatacc
agagcaacctgcttcgagggccagggcatcacctacagaggcacatggagcacagcagaa
aatggggctgaatgcatcaactggaatagcagtgccctgtcccagaagccctacagtgca
aggaggccaaatgccatcaagctgggccttgggaatcacaattactgcagaaacccagac
cgagacgtgaagccctggtgctatgtctttaaggcagggaagtataccacggagttctgc
agcacgccggcttgccctaagggaccaactgaggactgctatgttggaaaaggtgtgact
taccgtggcacccacagctttaccacatccaaggcctcctgcctcccatggaattccatg
atcctgataggcaagacttacacagcgtggagggccaactcccaggcacttggcctgggc
agacacaattattgccggaacccagatggggatgccaaaccttggtgccacgtgatgaag
gaccgaaagctgacatgggaatattgcgacatgtccccatgctccacctgcggcctgagg
caatacaaacagcctcagtttcgaattaaaggaggactcttcacagacatcacctcacac
ccttggcaggccgccatctttgtcaagaacaagaggtctccaggagagagattcctgtgt
ggaggggtgctgatcagttcctgctgggtgctatctgccgcccactgctttgtagagagg
tttccaccccatcatcttaaagtggtcttgggcagaacatacagagtggtccctggagag
gaggagcagacattcgagatcgaaaagtacatagtccataaggaatttgatgacgacact
tatgacaatgacatcgcattactgcagctgaggtcagattccagtcagtgtgcccaggag
agcagttctgtcggcactgcctgcctccctgaccccgacgtacagctccctgactggaca
gagtgtgagctttctggctacggcaagcatgaggcatcctctcctttcttctctgaccgg
ctgaaggaggctcacgtcagactgtatccgtccagccgctgtacctcacagcatctgttt
aacaaaaccatcacgagcaacatgctgtgtgcaggagacacccgaactgggggcaaccaa
gacgtccatgacgcgtgccagggtgactcaggaggccctctggtgtgcatgatcgataag
cggatgactttactgggcatcatcagctggggcctcggctgtgggcagaaggacgtgcca
gggatatacacaaaggtcactaattacctgaactggatccaagacaacatgaagcaatga

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