KEGG   Rattus norvegicus (rat): 293508Help
Entry
293508            CDS       T01003                                 

Gene name
Prkacb
Definition
protein kinase, cAMP dependent, catalytic, beta (EC:2.7.11.11)
Orthology
K04345  
protein kinase A [EC:2.7.11.11]
Organism
rno  Rattus norvegicus (rat)
Pathway
MAPK signaling pathway
Ras signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Apoptosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Hedgehog signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Olfactory transduction
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Bile secretion
Parkinson's disease
Prion diseases
Cocaine addiction
Amphetamine addiction
Morphine addiction
Amoebiasis
HTLV-I infection
Epstein-Barr virus infection
Viral carcinogenesis
Proteoglycans in cancer
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    293508 (Prkacb)
   04010 MAPK signaling pathway
    293508 (Prkacb)
   04310 Wnt signaling pathway
    293508 (Prkacb)
   04340 Hedgehog signaling pathway
    293508 (Prkacb)
   04020 Calcium signaling pathway
    293508 (Prkacb)
   04024 cAMP signaling pathway
    293508 (Prkacb)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    293508 (Prkacb)
   04210 Apoptosis
    293508 (Prkacb)
  Cell communication
   04540 Gap junction
    293508 (Prkacb)
 Organismal Systems
  Immune system
   04611 Platelet activation
    293508 (Prkacb)
   04062 Chemokine signaling pathway
    293508 (Prkacb)
  Endocrine system
   04911 Insulin secretion
    293508 (Prkacb)
   04910 Insulin signaling pathway
    293508 (Prkacb)
   04912 GnRH signaling pathway
    293508 (Prkacb)
   04913 Ovarian Steroidogenesis
    293508 (Prkacb)
   04915 Estrogen signaling pathway
    293508 (Prkacb)
   04914 Progesterone-mediated oocyte maturation
    293508 (Prkacb)
   04921 Oxytocin signaling pathway
    293508 (Prkacb)
   04918 Thyroid hormone synthesis
    293508 (Prkacb)
   04919 Thyroid hormone signaling pathway
    293508 (Prkacb)
   04916 Melanogenesis
    293508 (Prkacb)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    293508 (Prkacb)
   04270 Vascular smooth muscle contraction
    293508 (Prkacb)
  Digestive system
   04970 Salivary secretion
    293508 (Prkacb)
   04971 Gastric acid secretion
    293508 (Prkacb)
   04976 Bile secretion
    293508 (Prkacb)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    293508 (Prkacb)
   04961 Endocrine and other factor-regulated calcium reabsorption
    293508 (Prkacb)
  Nervous system
   04724 Glutamatergic synapse
    293508 (Prkacb)
   04727 GABAergic synapse
    293508 (Prkacb)
   04725 Cholinergic synapse
    293508 (Prkacb)
   04728 Dopaminergic synapse
    293508 (Prkacb)
   04726 Serotonergic synapse
    293508 (Prkacb)
   04720 Long-term potentiation
    293508 (Prkacb)
   04723 Retrograde endocannabinoid signaling
    293508 (Prkacb)
  Sensory system
   04740 Olfactory transduction
    293508 (Prkacb)
   04742 Taste transduction
    293508 (Prkacb)
   04750 Inflammatory mediator regulation of TRP channels
    293508 (Prkacb)
  Environmental adaptation
   04713 Circadian entrainment
    293508 (Prkacb)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    293508 (Prkacb)
   05203 Viral carcinogenesis
    293508 (Prkacb)
  Neurodegenerative diseases
   05012 Parkinson's disease
    293508 (Prkacb)
   05020 Prion diseases
    293508 (Prkacb)
  Substance dependence
   05030 Cocaine addiction
    293508 (Prkacb)
   05031 Amphetamine addiction
    293508 (Prkacb)
   05032 Morphine addiction
    293508 (Prkacb)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    293508 (Prkacb)
  Infectious diseases
   05166 HTLV-I infection
    293508 (Prkacb)
   05169 Epstein-Barr virus infection
    293508 (Prkacb)
   05146 Amoebiasis
    293508 (Prkacb)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     293508 (Prkacb)
Protein kinases [BR:rno01001]
 Serine/threonine protein kinases: AGC group
  PKA family
   293508 (Prkacb)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
2q44
AA seq 351 aa AA seqDB search
MGNTAIAKKGSEVESVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVML
VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT
TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF
NT seq 1056 nt NT seq  +upstreamnt  +downstreamnt
atggggaacacggcgatcgccaagaaaggcagcgaagtggagagcgtgaaagaattccta
gccaaagccaaagaagactttctgaggaaatgggagaaccctcccccgagtaatgctggg
cttgaggattttgaaaggaaaaaaacccttggaacgggttccttcggaagagtcatgctg
gtaaagcataaagccactgagcagtactacgccatgaagatcttagacaagcagaaggtc
gttaagctaaagcaaatagagcacactctgaatgagaagagaatcctgcaggcagtggag
ttcccgttccttgttcggctggagtattcttttaaggataattctaatttatacatggtt
atggaatacgttcctgggggggaaatgttttcacatctaagaagaattggaaggttcagt
gaaccccatgctcgtttctatgcagctcagatcgtgctaacatttgagtacctccattcc
ctcgacctcatctacagagatctcaagccggaaaacctcttaattgaccaccagggttac
atccaggtcacagattttgggttcgccaagagagtcaagggcaggacttggacattgtgt
ggcaccccagagtacctggccccagagatcatcctcagcaagggttacaataaggcagtg
gactggtgggcattgggtgtactgatctacgagatggctgctggctaccccccgttcttt
gctgaccagccaattcagatttatgagaagattgtttccggaaaggtccgcttcccgtcg
cacttcagttccgatctcaaggaccttctgcggaatctgctgcaggtggatctgacaaag
cggtttgggaacctgaagaatggcgtgagtgacatcaagacccacaagtggtttgctacg
accgactggatcgcgatttaccagagaaaggttgaggctccattcataccaaaattcaga
ggctctggcgataccagcaacttcgatgactatgaagaagaagaaatccgagtgtctata
acagaaaaatgtggaaaggagttttgtgaattttag

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