| Entry |
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| Gene name |
Bace1, Bace
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| Definition |
beta-site APP cleaving enzyme 1 (EC:3.4.23.46)
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| Orthology |
| beta-site APP-cleaving enzyme 1 (memapsin 2) [EC: 3.4.23.46] |
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| Organism |
rno Rattus norvegicus (rat)
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| Pathway |
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| Class |
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH: rno05010]
 |
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: RGD: Ensembl: UniProt: |
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| Position |
8q22
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| AA seq |
501 aa  
MAPALRWLLLWVGSGMLPAQGTHLGIRLPLRSGLAGPPLGLRLPRETDEEPEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKSVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHIPNIFSLQLCGAGFPLNQTEALASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAVSQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTADMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK |
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| NT seq |
1506 nt  +upstreamnt +downstreamnt
atggccccggcgctgcgctggctcctgctatgggtgggctcgggaatgctgcctgcccag
ggaacccatctcggtatccgactgccccttcgcagcggcctggcagggccacccctgggc
ctgaggctgccccgggagacggacgaggaacctgaggagcctggccggagaggcagcttt
gtggagatggtggacaacctgaggggaaagtccggccagggctactatgtggagatgacc
gtgggcagccccccacagacgctcaacatcctggtggacacgggcagtagtaattttgca
gtgggggctgccccacaccctttcctgcatcgatactaccaaaggcagctgtccagtaca
taccgagacctccgaaagtctgtgtatgtgccctacacccagggcaagtgggagggggaa
ctgggcactgacctggtgagcatccctcatggccccaacgtcactgtgcgtgccaacatt
gctgccatcactgaatcggacaagttcttcatcaatggttccaactgggagggcatccta
gggctggcctatgctgagattgccaggcctgacgactccttggagcccttttttgactcc
ctggtgaagcagacccacattccgaacatcttttccctgcagctctgtggcgctggcttc
cccctcaaccagactgaggcactggcctcggtgggagggagcatgatcattggtggtatc
gaccattccctatacactggcagtctctggtacacacccatccggcgggagtggtattat
gaagtgatcattgtacgtgtagaaatcaatggtcaagatctgaaaatggactgcaaggag
tacaactatgacaagagcatcgtggacagtggcaccaccaaccttcgtttgcccaagaaa
gtatttgaagctgcagtcaagtccatcaaggcagcctcctcgacggagaagttcccggat
ggcttttggctaggggagcagctggtgtgctggcaagcaggcacgaccccttggaacatt
ttcccagtcatttcactttacctcatgggtgaagtcaccaatcagtccttccgcatcacc
atccttcctcagcaatacctacggccagtggaagatgtggccacgtcccaagacgactgt
tacaagttcgccgtctcacagtcatccacaggcaccgttatgggagcggtcatcatggaa
ggcttctatgtggtctttgatcgagcccgaaagcgaattggctttgctgtcagcgcttgc
catgtgcacgatgagttcaggacggcggcagtggaaggtccgtttgtcacggcagacatg
gaagactgtggctacaacattccacagacagatgagtcaacacttatgaccatagcctat
gtcatggctgccatctgcgccctcttcatgttgccactctgcctcatggtatgtcagtgg
cgctgcctacgctgcctgcgccatcagcatgatgactttgctgatgacatctccctgctg
aaataa |
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