KEGG   Rattus norvegicus (rat): 29433Help
Entry
29433             CDS       R.norvegicus                           
Gene name Pak3
Definition p21 protein (Cdc42/Rac)-activated kinase 3 (EC:2.7.11.1)
Orthology K05733  p21-activated kinase 3 [EC:2.7.11.1]
Pathway rno04012  ErbB signaling pathway
rno04360  Axon guidance
rno04510  Focal adhesion
rno04660  T cell receptor signaling pathway
rno04810  Regulation of actin cytoskeleton
rno05211  Renal cell carcinoma
Class Metabolism; Enzyme Families; Protein kinases
Environmental Information Processing; Signal Transduction; ErbB
signaling pathway [PATH:rno04012]
Cellular Processes; Cell Motility; Regulation of actin cytoskeleton
[PATH:rno04810]
Cellular Processes; Cell Communication; Focal adhesion
[PATH:rno04510]
Organismal Systems; Immune System; T cell receptor signaling pathway
[PATH:rno04660]
Organismal Systems; Development; Axon guidance [PATH:rno04360]
Human Diseases; Cancers; Renal cell carcinoma [PATH:rno05211]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: Pkinase Pkinase_Tyr PBD APH DSHCT Kdo
PROSITE: PROTEIN_KINASE_ST PROTEIN_KINASE_ATP CRIB
         PROTEIN_KINASE_DOM
Motif
Other DBs NCBI-GI: 9506947
NCBI-GeneID: 29433
RGD: 3251
RATMAP: ENSRNOG00000004676
Ensembl: ENSRNOG00000004676
UniProt: Q62829
Position Xq14
AA seq 544 aa AA seqDB search
MSDSLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN
KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVL
DVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHQSNTKTASEPPLAPPVSEEEDEEEEE
EEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEATPPSAENANSSTLYRNTDRQ
RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN
LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD
EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS
TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP
ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLILAAKEAIK
NSSR
NT seq 1635 nt NT seq  +upstreamnt  +downstreamnt
atgtctgacagcttggataacgaagaaaaacctccagctcccccactgaggatgaacagt
aacaaccgagattcttcagcactcaaccacagctccaaaccactgcccatggccccggaa
gagaagaataagaaagccaggcttcgctctatcttcccaggaggaggggataaaaccaat
aagaagaaagagaaagaacgcccagagatctctcttccttcagactttgagcatacgatt
catgtgggttttgatgcagtcaccggggaattcactggaattcctgaacaatgggctcga
ctgctccaaacctccaacattacaaaactggaacagaagaagaacccacaggctgttctg
gatgttctcaagttttacgactccaaagaaacagtcaacaaccagaaatacatgagcttt
acatcaggagataaaagtgcccatggatatatagcagcacatcagtcgaataccaaaaca
gcttcagaacctcctttggctcctcctgtatctgaagaagaggatgaagaagaggaagag
gaagaagatgataatgagcccccgcctgtcattgcaccaagaccagagcatacaaaatca
atctatactcgttctgtggttgagtcaattgcttcaccagcagcaccaaataaagaagcc
accccaccttctgctgagaatgccaattccagtactttgtacaggaatacagatcggcaa
agaaaaaaatccaagatgacagatgaggagatcctagagaagctaagaagcattgtgagt
gttggggacccaaagaagaaatatacaagatttgaaaaaattggccaaggggcatcagga
actgtttacacagcactagacattgcgacaggacaagaggtggctataaagcaaatgaac
cttcaacagcagcccaaaaaggaattaattattaatgaaattcttgtcatgagggaaaat
aagaaccccaatattgtcaattatttagatagctacttagtgggtgatgaactgtgggta
gtcatggaatacttggctggtggctctttgactgacgtggtcacagaaacctgtatggat
gaaggacagatagcagccgtctgtagagagtgcctccaagctttggatttcttgcactca
aaccaagtgatccacagagatataaagagtgacaatattctcctcgggatggatggttct
gttaaactgactgattttggattctgtgcccaaatcactcctgagcaaagtaaacgaagc
actatggtgggaactccctattggatggcacctgaggtggtaactcgaaaagcttatggc
ccgaaagttgatatctggtctctgggaatcatggccattgaaatggtggaaggtgaaccc
ccttaccttaatgaaaatccactcagggccttatatctgatagccactaatggaacccca
gagctccagaatcccgagagactgtcagctgtattccgtgacttcttaaatcgctgtctt
gagatggatgtggatagacgagggtctgccaaggagcttttgcagcatccatttttaaaa
ttagccaagcccctgtccagcctcactcctctgattcttgctgcaaaggaagccattaag
aacagtagccgttag
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