KEGG R.norvegicus: 296078

Rattus norvegicus (rat): 296078

Entry

296078 CDS R.norvegicus

Gene name Pak6

Definition p21 protein (Cdc42/Rac)-activated kinase 6 (EC:2.7.11.1)

Orthology K05735 p21-activated kinase 6 [EC:2.7.11.1]

Pathway rno04012 ErbB signaling pathway
rno04360 Axon guidance
rno04510 Focal adhesion
rno04660 T cell receptor signaling pathway
rno04810 Regulation of actin cytoskeleton
rno05211 Renal cell carcinoma

Class Metabolism; Enzyme Families; Protein kinases
Environmental Information Processing; Signal Transduction; ErbB
signaling pathway [PATH:rno04012]
Cellular Processes; Cell Motility; Regulation of actin cytoskeleton
[PATH:rno04810]
Cellular Processes; Cell Communication; Focal adhesion
[PATH:rno04510]
Organismal Systems; Immune System; T cell receptor signaling pathway
[PATH:rno04660]
Organismal Systems; Development; Axon guidance [PATH:rno04360]
Human Diseases; Cancers; Renal cell carcinoma [PATH:rno05211]

SSDB

Motif Pfam: Pkinase Pkinase_Tyr PBD APH Kdo
PROSITE: PROTEIN_KINASE_ATP CRIB PROTEIN_KINASE_DOM

Other DBs NCBI-GI: 157817492
NCBI-GeneID: 296078
RGD: 1306213
RATMAP: ENSRNOG00000007925
Ensembl: ENSRNOG00000007925

Position 3q35

AA seq 681 aa
MFRKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDTLRRPKPVVDPSRIT
RVQLQPMKTVVRGSSVPTEGYISGLLNDIQKLSAISSNTLRGRSPTSRRRAQSLGLLGDD
QWAADPDMYLQSPQSERTDPHGVYLSCNGGTPAGHRQTPWPEPQSPQALPNGMAAKAQSL
GPAEFQGASQRCLQLGACLQSSPPGTSPPMATGRRGVKVTKHSSEEARPQSCLVGSAIGR
PGGEGSPSPKTQESSLKHRLFRSMFLSTPATGSASSSKPVPLPQNKLNSAFRPPQKDSSS
NLVAKAQSLPSDQPTGTFSPLTTSDTSSPQKSLRTAPATGPLPGRSSPAGSPRTRHAQIS
TSNLYLPQDPTVAKGALGGEDTGIVTHEQFKAALRMVVDQGDPRLLLDSYVKIGEGSTGI
VCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHLNVVEMYKSYLVGEELWVL
MEFLQGGALTDIISQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRV
KLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPP
YFSDSPVQAMKRLRDSPPPKLKNSYKVSPVLRDFLERMLVREPQERATAQELLDHPFLLQ
TGLPECLVPLIQLYRKQTSTC

NT seq 2046 nt +upstreamnt +downstreamnt
atgttccgaaagaagaagaagaaacgccctgagatatcagccccacagaacttccagcac
cgtgttcacacctcatttgaccccaaggaaggcaagttcgtgggcctgcccccacaatgg
cagaacatcctggatactctgaggcggcccaagcctgtggtggatccttctcgaatcaca
cgggtgcagttgcagcccatgaagacggtagtacggggcagctcagtgcccacagagggc
tacatctccgggctgctcaatgacattcagaagttgtcagctatcagctccaacactctg
cgtggacgcagccccaccagccggcggcgggcacagtccctggggctgctaggagatgat
cagtgggcggctgacccggatatgtacctccaaagtcctcagtctgagcgcactgatccc
catggcgtctacctcagctgtaatgggggcacaccagcaggtcacaggcaaacgccatgg
ccagaaccacagagcccacaggccctgcccaatggcatggctgccaaggcacagtcgctg
ggccccgctgagttccagggtgcctcccaacgctgcctgcagctgggtgcctgcctacag
agttccccacctggtacctcaccccctatggccacagggaggcgtggggtgaaggttacc
aagcatagctcggaagaggctcgaccacaatcttgcctggtgggctcagccattggcaga
ccaggtggagaaggcagccccagccctaagacccaggaaagcagcctcaagcaccggctc
ttccgcagcatgttcctgtccactcccgccacaggctctgcaagcagcagcaagccggtc
cctctgccacagaacaagctcaattctgctttccgaccaccacaaaaagattcctcttca
aacctggtagccaaggcccagtccttgccctcagatcagcccacggggaccttcagtcct
ctgaccacctcagataccagcagtccccagaagtccctccgcacagccccagccactggt
ccacttccaggccggtcttctccagcaggctccccccgcacccggcatgcccagatcagc
accagcaatctatacctgccccaggaccccacagtggccaagggggccctgggtggcgaa
gacacaggcatcgtaacacatgagcagttcaaagctgcgctcaggatggtggtggaccag
ggtgaccctcggctgctgctggacagctatgtgaagattggggagggctccacgggcatt
gtgtgtctggcccgggagaagcattcaggtcgccaggtagcagtcaagatgatggacctc
agaaagcagcaacgcagggaactgctctttaatgaggtggtgatcatgcgtgactaccag
cacctcaatgtggtggagatgtacaagagttacctggtaggagaggagctgtgggtgctg
atggagttcctgcagggcggggccctcacagacatcatctcccaagtcagactcaatgag
gaacagattgctactgtgtgtgaagctgtgcttcaggccttggcttacctgcacgcccag
ggtgtcatccaccgagacatcaagagtgattccatcctgctgacccttgatggcagggtg
aagctctcagactttgggttctgtgctcagatcagcaaagatgtccccaagagaaagtct
ctcgtaggaactccatactggatggctcctgaggtgatctccagatccctgtacgctact
gaggtggatatctggtctctgggcatcatggtgattgagatggtggatggagaaccccct
tacttcagcgactccccagtgcaagccatgaagaggctccgggacagccccccacccaag
ctaaagaactcttacaaggtctctccagtgctgcgagacttcctggaacgaatgctggta
cgggaaccccaagagagagccacagcccaggagctcctggatcacccctttctgctgcag
acggggctgcccgagtgtctggtgcctctgatacagctctaccgcaagcagacctccacc
tgctga

All links

Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
   UNIGENE (1)   
   ENSEMBL-RNO (1)   
   RATMAP-RNO (1)   
   RGD-RNO (1)   
Protein sequence (4)   
   RefSeq(pep) (3)   
   IPI (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (8)   
   Pfam (5)   
   PROSITE (3)   
All databases (31)

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