KEGG   Rattus norvegicus (rat): 298296
Entry
298296            CDS       T01003                                 
Symbol
Pcsk9
Name
(RefSeq) proprotein convertase subtilisin/kexin type 9 precursor
  KO
K13050  proprotein convertase subtilisin/kexin type 9 [EC:3.4.21.-]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04979  Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    298296 (Pcsk9)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:rno01002]
    298296 (Pcsk9)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:rno03110]
    298296 (Pcsk9)
Peptidases and inhibitors [BR:rno01002]
 Serine peptidases
  Family S8: subtilisin family
   298296 (Pcsk9)
Chaperones and folding catalysts [BR:rno03110]
 Intramolecular chaperones
  Subtilisin family
   298296 (Pcsk9)
SSDB
Motif
Pfam: PCSK9_C1 PCSK9_C2 Peptidase_S8 PCSK9_C3 Inhibitor_I9
Other DBs
NCBI-GeneID: 298296
NCBI-ProteinID: NP_954862
RGD: 728909
Ensembl: ENSRNOG00000006280
UniProt: P59996 A6JYM6
Position
5:complement(126440102..126462507)
AA seq 691 aa
MGIRCSTWLRWPLSPQLLLLLLLCPTGSRAQDEDGDYEELMLALPSQEDSLVDEASHVAT
ATFRRCSKEAWRLPGTYVVVLMEETQRLQVEQTAHRLQTWAARRGYVIKVLHVFYDLFPG
FLVKMSSDLLGLALKLPHVEYIEEDSLVFAQSIPWNLERIIPAWQQTEEDSSPDGSSQVE
VYLLDTSIQSGHREIEGRVTITDFNSVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGV
AKGTSLHSLRVLNCQGKGTVSGTLIGLEFIRKSQLIQPSGPLVVLLPLAGGYSRILNTAC
QRLARTGVVLVAAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDL
FAPGKDIIGASSDCSTCYMSQSGTSQAAAHVAGIVAMMLNRDPALTLAELRQRLILFSTK
DVINMAWFPEDQRVLTPNRVATLPPSTQETGGQLLCRTVWSAHSGPTRTATATARCAPEE
ELLSCSSFSRSGRRRGDRIEAIGGQQVCKALNAFGGEGVYAVARCCLLPRVNCSIHNTPA
ARAGPQTPVHCHQKDHVLTGCSFHWEVENLRAQQQPLLRSRHQPGQCVGHQEASVHASCC
HAPGLECKIKEHGIAGPAEQVTVACEAGWTLTGCNVLPGASLPLGAYSVDNVCVARIRDA
GRADRTSEEATVAAAICCRSRPSAKASWVHQ
NT seq 2076 nt   +upstreamnt  +downstreamnt
atgggcatccgctgctctacatggttgcggtggccgctgtcgccgcagctgctgttgttg
ctgctactgtgccccacaggctcccgtgcccaggacgaggacggagactacgaagagctg
atgctcgccctcccgtcccaggaggatagcctggttgatgaggcctcacacgtggccacc
gccaccttccgccgttgctccaaggaggcctggaggctgccaggaacctacgtggtggtg
ctgatggaggagacccagcggctgcaggttgaacaaactgcccatcgcctgcagacctgg
gcggcccgccggggctatgtcatcaaggttctgcatgtcttttatgacctcttccctggc
ttcttggtgaagatgagcagtgacctgttgggcctggccctgaagttgccccatgtggag
tacatcgaggaagactcattagtcttcgcccagagcatcccatggaacctggagcggatt
atcccagcgtggcagcagacagaggaagatagctcccctgacggaagtagccaggtggag
gtgtatctcttagataccagcatccagagtggccaccgggagatcgagggcagagttacc
atcactgacttcaacagtgtgcctgaggaggacgggacacgtttccacagacaggcgagc
aagtgtgacagccatggcacccacctagcaggtgtggtcagcggccgggatgctggtgtg
gccaagggcaccagtctgcacagtctgcgtgtgctcaactgtcaagggaagggcacagtc
agcggcaccctcataggcctggagtttattcggaagagccagctaatccagccttcgggg
ccactcgtggtgctgctgcccctggcgggtgggtatagccggatccttaacactgcctgc
cagcgcctggcaaggactggggtagtgctggtggcagcagctgggaatttccgagatgat
gcctgcctctactccccagcctctgctccagaggtcattacagttggggccactaatgcc
caggaccagccagtcaccctggggactttggggacaaactttggacgctgtgtggatctc
tttgcccccgggaaggacatcatcggagcctccagtgactgtagcacgtgctacatgtca
cagagtgggacgtcacaagctgctgcccacgtggctggcattgtggctatgatgctgaac
cgggatccagcacttaccctggctgagctgcggcagaggttgatcctcttctctaccaaa
gatgtcatcaacatggcctggttccctgaggaccagcgggtgctgacccccaaccgggtg
gccacactgccccccagcacccaggagacaggcgggcagctgctctgccggacagtgtgg
tccgcccactcagggcccacccgtacagcaacagccacagcccgctgtgcccctgaagag
gaactgctgagctgctccagcttctccaggagcgggaggcgacggggtgatcgaattgag
gccatagggggccagcaggtctgcaaggccctcaatgcatttgggggtgagggtgtctat
gctgtcgcaaggtgctgcctgcttccccgtgtcaactgcagcatccacaacactcctgca
gccagagctggtccgcagacccccgtccactgccaccagaaggaccatgttctcacaggc
tgcagcttccactgggaagtggaaaaccttagagcccagcagcagcctctgctgaggtcc
agacatcaacctggccaatgcgttggccaccaggaggccagtgtccacgcttcctgctgc
catgctccaggtctggaatgcaaaatcaaggagcatggcatcgcaggtcctgcagagcag
gtcaccgtggcctgtgaggcaggatggaccctgactggatgcaacgttctccctggggca
tccctccctctgggggcctacagtgtggacaacgtgtgtgtggcacgaatccgtgatgct
ggtagagcggacaggaccagtgaagaagccacggtagctgctgccatctgctgccggagc
cggccttcggcaaaggcctcctgggttcaccagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (5)   
   Pfam (5)   
All databases (27)   

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