KEGG   Rattus norvegicus (rat): 298947Help
Entry
298947            CDS       R.norvegicus                           
Gene name Pik3cg
Definition phosphoinositide-3-kinase, catalytic, gamma polypeptide
(EC:2.7.1.153)
Orthology K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase
        [EC:2.7.1.153]
Pathway rno00562  Inositol phosphate metabolism
rno04012  ErbB signaling pathway
rno04062  Chemokine signaling pathway
rno04070  Phosphatidylinositol signaling system
rno04150  mTOR signaling pathway
rno04210  Apoptosis
rno04370  VEGF signaling pathway
rno04510  Focal adhesion
rno04620  Toll-like receptor signaling pathway
rno04630  Jak-STAT signaling pathway
rno04650  Natural killer cell mediated cytotoxicity
rno04660  T cell receptor signaling pathway
rno04662  B cell receptor signaling pathway
rno04664  Fc epsilon RI signaling pathway
rno04666  Fc gamma R-mediated phagocytosis
rno04670  Leukocyte transendothelial migration
rno04722  Neurotrophin signaling pathway
rno04810  Regulation of actin cytoskeleton
rno04910  Insulin signaling pathway
rno04914  Progesterone-mediated oocyte maturation
rno04930  Type II diabetes mellitus
rno04960  Aldosterone-regulated sodium reabsorption
rno05200  Pathways in cancer
rno05210  Colorectal cancer
rno05211  Renal cell carcinoma
rno05212  Pancreatic cancer
rno05213  Endometrial cancer
rno05214  Glioma
rno05215  Prostate cancer
rno05218  Melanoma
rno05220  Chronic myeloid leukemia
rno05221  Acute myeloid leukemia
rno05222  Small cell lung cancer
rno05223  Non-small cell lung cancer
Class Metabolism; Carbohydrate Metabolism; Inositol phosphate metabolism
[PATH:rno00562]
Environmental Information Processing; Signal Transduction; ErbB
signaling pathway [PATH:rno04012]
Environmental Information Processing; Signal Transduction; VEGF
signaling pathway [PATH:rno04370]
Environmental Information Processing; Signal Transduction; Jak-STAT
signaling pathway [PATH:rno04630]
Environmental Information Processing; Signal Transduction;
Phosphatidylinositol signaling system [PATH:rno04070]
Environmental Information Processing; Signal Transduction; mTOR
signaling pathway [PATH:rno04150]
Cellular Processes; Cell Motility; Regulation of actin cytoskeleton
[PATH:rno04810]
Cellular Processes; Cell Growth and Death; Apoptosis [PATH:rno04210]
Cellular Processes; Cell Communication; Focal adhesion
[PATH:rno04510]
Organismal Systems; Immune System; Toll-like receptor signaling
pathway [PATH:rno04620]
Organismal Systems; Immune System; Natural killer cell mediated
cytotoxicity [PATH:rno04650]
Organismal Systems; Immune System; T cell receptor signaling pathway
[PATH:rno04660]
Organismal Systems; Immune System; B cell receptor signaling pathway
[PATH:rno04662]
Organismal Systems; Immune System; Fc epsilon RI signaling pathway
[PATH:rno04664]
Organismal Systems; Immune System; Fc gamma R-mediated phagocytosis
[PATH:rno04666]
Organismal Systems; Immune System; Leukocyte transendothelial
migration [PATH:rno04670]
Organismal Systems; Immune System; Chemokine signaling pathway
[PATH:rno04062]
Organismal Systems; Endocrine System; Insulin signaling pathway
[PATH:rno04910]
Organismal Systems; Endocrine System; Progesterone-mediated oocyte
maturation [PATH:rno04914]
Organismal Systems; Excretory System; Aldosterone-regulated sodium
reabsorption [PATH:rno04960]
Organismal Systems; Nervous System; Neurotrophin signaling pathway
[PATH:rno04722]
Human Diseases; Cancers; Pathways in cancer [PATH:rno05200]
Human Diseases; Cancers; Colorectal cancer [PATH:rno05210]
Human Diseases; Cancers; Pancreatic cancer [PATH:rno05212]
Human Diseases; Cancers; Glioma [PATH:rno05214]
Human Diseases; Cancers; Acute myeloid leukemia [PATH:rno05221]
Human Diseases; Cancers; Chronic myeloid leukemia [PATH:rno05220]
Human Diseases; Cancers; Melanoma [PATH:rno05218]
Human Diseases; Cancers; Renal cell carcinoma [PATH:rno05211]
Human Diseases; Cancers; Prostate cancer [PATH:rno05215]
Human Diseases; Cancers; Endometrial cancer [PATH:rno05213]
Human Diseases; Cancers; Small cell lung cancer [PATH:rno05222]
Human Diseases; Cancers; Non-small cell lung cancer [PATH:rno05223]
Human Diseases; Metabolic Diseases; Type II diabetes mellitus
[PATH:rno04930]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: PI3K_rbd PI3K_C2 PI3Ka
Motif
Other DBs NCBI-GI: 157818277
NCBI-GeneID: 298947
RGD: 1306468
RATMAP: ENSRNOG00000009385
Ensembl: ENSRNOG00000009385
Position 6q16
AA seq 639 aa AA seqDB search
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKMMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIVNNCIFIVIHRGTTSQTIKVSADDT
PDTILQSFFTKMAKKKSLMNIPESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRNEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKLFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPSLSSKASVETPGSESKGKAQLLYYVNLLLIDHRFLLRHGGY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSEKT
NT seq 1920 nt NT seq  +upstreamnt  +downstreamnt
atggagctggagaactatgaacaacctgtggttctgagagaggacaacctccgcaggcgc
cggaggatgaagccacgcagcgcagcaggcagcctgtcttccatggagctcatccccatt
gagttcgtactgcccaccagccagcgcatcagcaagacaccggaaacggccctgctgcat
gtggctggccacggcaatgtggagcagatgaaagctcaggtgtggttacgcgcactggag
accagtgtggctgcggaattctaccaccgattaggtccggaccaattcctcctcctctac
cagaagaagggacagtggtatgagatctacgataggtaccaagtggtgcagaccctagac
tgcctacgttactggaagatgatgcacaagagccccggccagatccacgtggtacagcga
catgtaccttctgaggagaccctggctttccagaagcagctcacctccctgattggctac
gacgtcactgacatcagcaacgtgcacgatgatgagctagaattcactcgccgccgtctg
gttacgccccgcatggctgaagtggctggccgggatgccaaactctatgccatgcaccct
tgggtgacctccaaacctcttccagactacctgtcaaaaaaaattgtcaacaattgcatt
ttcattgtcatccatcgtggtaccaccagtcaaaccatcaaggtctccgcagatgatact
cctgacaccatccttcagagcttcttcaccaagatggccaagaagaagtccctaatgaat
atcccagaaagtcaaagtgagcaggattttgtgctgcgggtctgtggccgtgatgagtac
ctagtaggtgaaacgcccctcaaaaatttccagtgggtgaggcagtgcctcaagaacgga
gaggaaatacacctggtgctcgacacgcctccagacccggccctagatgaggtgaggaac
gaagaatggccgctggtggatgactgcactggagtcaccggctaccatgagcagctgacc
atccatggcaaggaccacgagagcgttttcacagtgtctttgtgggactgtgaccgaaag
ttcagggtcaagatcagaggcattgatatccctgtcttgcctcggaacaccgacctcact
gtttttgtggaagcaaatatccagcatgggcaacaagtcctctgccaaaggagaaccagc
cctaagctcttcacagaagaggtgctctggaatgtgtggctggagtttggcattaaaatc
aaagacttgcccaaaggggccctactgaacctacagatctactgctgcaaaaccccatca
ctgtccagtaaggcttccgtagagacgccaggctccgagtccaagggcaaagcccagctc
ctctattacgtgaacttgctgttgatagaccaccgcttcctcctccgccatgggggctac
gtgctccacatgtggcagatatctgggaaggcagaggaacagggcagcttcaatgccgac
aagctcacctccgcaaccaatcctgacaaggagaactcaatgtccatttccatcttgctg
gacaactactgtcaccccattgctttgcctaagcaccggcctactccggacccagaagga
gacagagttcgagctgaaatgcccaatcagcttcgaaagcaattggaggcaatcatagcc
acagatccacttaaccccctcacagcagaggacaaagaattgctctggcattttagatat
gaaagcctgaagcatccaaaggcataccctaaactattcagctcagtaaagtggggacag
caagaaattgttgccaaaacataccagctattagccagaagggagatctgggatcaaagt
gctttggatgttggcttaaccatgcaactcctggactgcaacttttcagagaaaacgtaa
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