KEGG R.norvegicus: 299611

Rattus norvegicus (rat): 299611

Entry

299611 CDS R.norvegicus

Gene name Apc2

Definition adenomatosis polyposis coli 2

Orthology K02085 adenomatosis polyposis coli protein

Pathway rno04310 Wnt signaling pathway
rno04810 Regulation of actin cytoskeleton
rno05200 Pathways in cancer
rno05210 Colorectal cancer
rno05213 Endometrial cancer
rno05217 Basal cell carcinoma

Class Environmental Information Processing; Signal Transduction; Wnt
signaling pathway [PATH:rno04310]
Cellular Processes; Cell Motility; Regulation of actin cytoskeleton
[PATH:rno04810]
Human Diseases; Cancers; Pathways in cancer [PATH:rno05200]
Human Diseases; Cancers; Colorectal cancer [PATH:rno05210]
Human Diseases; Cancers; Basal cell carcinoma [PATH:rno05217]
Human Diseases; Cancers; Endometrial cancer [PATH:rno05213]

SSDB

Motif Pfam: APC_basic Suppressor_APC APC_crr Arm SAMP bZIP_1 HALZ KAP
PROSITE: PHOSPHOPANTETHEINE PRO_RICH SER_RICH NLS_BP

Other DBs NCBI-GI: 158186657
NCBI-GeneID: 299611
RGD: 1308256
RATMAP: ENSRNOG00000033791
Ensembl: ENSRNOG00000033791

Position 7q11

AA seq 2281 aa
MASSVASYEQLVRQVEALKAENTHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKLEQE
ARVLVSSGQTEVLEQLKALQTDISSLYNLKFHAPALGPEPAAQTPEGSPVHGPAPSKDSF
GELSRATIRLLEELDQERCFLLSEIEKEEKEKLWYYSQLQGLSKRLDELPHVDTQFSMQM
DLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRASRLEQIDKELLEAQDRVQQTEPQA
LLAVKPVAVEEQEAEVPTHPEDVTPQPGNSKVEVVFWLLSMLATRDQEDTARTLLAMSSS
PESCVAMRRSGCLPLLLQILHGTEAGSVGRTGTPGAPGAKDARMRANAALHNIVFSQPDQ
GLARKEMRVLHVLEQIRAYCETCWDWLQARDSGTESGTGDTPVPIEPQICQAACAVMKLS
FDEEYRRAMNELGGLQAVAELLQVDYEMHKMTQDPLNLALRRYAGMTLTNLTFGDVANKA
TLCARRGCMEAIVAQLASESEELHQVVSSILRNLSWRADINSKKVLREVGSMTALMECVL
RASKESTLKSVLSALWNLSAHSTENKAAICQVDGALGFLVSTLTYRCQGNSLAVIESGGG
ILRNVSSLIATREDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSARSPRDQEL
LWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLAHRPAKYQAAAMAVSPGTCVPSLYVRK
QRALEAELDTRHLVHALGHLEKQGLPEAETTSKKPLPPLRHLDGLVQDYASDSGCFDDDD
APSLAAAATTAEPASPAVMSMFLGGPFLQGQALARTPPARQGGLEAEKETGGEAAVAAKA
KAKLALAVARIDRLVEDISALHTSSDDSFSLSSGDPGQEAPREGRAQSCSPCRGTEGGRR
EAGSRAHPLLRLKAAHTSLSNDSLNSGSTSDGYCTREHMTPCPLAVLTEHRDGPVCGQTR
PSRLDLDLPSRAELPARDTAATDARVRTIKLSPTYQHVPLLDGAPGAGVRPLVGLGTSPG
TRKQAWIPADSLSKVPEKLVASPLPVTSKVLQKLVAQDGPMSLSRCSSLSSLSSTGHAVP
SQVENLDDSDSSLEELEEAGPGEAELDRAWRASGSTSLPVSIPAPQRGRSRGLGVEDATP
SSSSENCVQETPLVLSRCSSVSSLGSFESRSIASSIPSDPCSALGSGTVSPSELPDSPGQ
TMPPSRSRTPPAPPGQPEASQFSLQWESYVKRFLDIADCRERCQPPSELDAGSVRFTVEK
PDENFSCASSLSALALHELYVQQDVELRLRPPACPERAVGGGGGHRRRDEATSRLDGPAP
AGSRARSAADKELEALRECLGAAMPARLRKVASALVPGRRALPVPVYMLVPAPARGDDSG
TDSAEGTPVNFSSAASLSDETLQGPSRDKPARPGDRQKPTGRAAPARQTRGHRPKAAGAG
AGKSTEHTRGANRNRAGLELPLSRPQSARSNRDGSCQTRTRGDGALQSLCLTTPTEEAVY
CFYDSDEEPPATAPPTRRASAIPRALKREKPAGRKETPTRATQPATLPVRAQPRLIVDET
PPCYSLTSSASSLSEPEASEQPACHPRVEEQGSKQDSSPRAEEELLQRCISLAMPRRRTQ
VPSSRRRKPRAVRSDIRPTELPQKCREEVPGSDPASDLDSVEWQAIQEGANSIVTWLHQA
AAKASLEASSESDSLLSLVSGLSASSTLQPSKLRKGRKPVAEAGGAWRPEKRGTTSTKGS
GSPRFPSGPEKAKGTQKTMAGESAMLRGRTVIYTASPASRAQSKGISGPCSAPKKMGTSG
TTQPETATKTPSPEQQRSRSLHRPGKISELAALSHPPRSATPPARLTKTPSSSSSQTSPA
SQSLPRRSPLATPTGGPLPGPGGSPVPKSPARALLAKQHKTQKSPVRIPFMQRPARRVPP
PLARPSPEPGSRGRAGAEGTPGARGSRLGLVRVASTRSSGSESSDRSGFRRQLTFIKESP
GLLRRRRSELSSADSTVSTSQTASPCRGRPALPAVFLCSSRCDELRASPRQPLAAQRVPQ
AKPGLAPRAPRRTSSESPSRLPVRATPGRPETVKRYASLPHISVSRRPDSAVSVPTTQAN
ATRRGSDGEARPLPRVAAPGTTWRRIKDEDVPHILRSTLPATALPLRGSSPEDSPAGTPH
RKTSDAVVQTEDVATSKTNSSTSPSLESRDPPQAPISGPVAPLGSDVDGPVLAKPPASAP
FTHEGLSVVTGGFPTSRHGSPSRAARVPPFNYVPSPMVVATMTSDSAVEKAPVTSPASLL
E

NT seq 6846 nt +upstreamnt +downstreamnt
atggccagctccgtggcctcgtacgagcagctggtgcgccaggtggaggccttgaaggcg
gagaacactcacttaagacaggagctgagggataactctagccatctctccaagctggag
acagagacttctggcatgaaggaggtcctgaaacaccttcagggcaagctggagcaggag
gcgagagtgctggtatcctccgggcagacagaagtgttagagcaactgaaagctcttcag
actgacatcagtagcctctataacctgaagttccatgccccggccctgggccctgagcct
gctgcccagactccagagggaagcccagtacatggccctgcaccgtccaaggacagcttc
ggagagctgagccgggccaccatccgcctgctggaagaactagaccaggagagatgcttc
ctgctgagcgagatagagaaagaggagaaggagaagctgtggtattactctcagctccag
ggcctctctaagcgcttggatgaactgccacacgtagacacgcagttttcgatgcagatg
gatctaattcggcagcagctggagttcgaagcccagcacatccgctcgttgatggaggag
cgcttcggtacctcagacgagatggtgcagcgggctcagatccgggcttcacgcctggag
cagattgacaaggagctgttggaagcccaggaccgggtgcagcagacggagccccaggcg
ctgctggcggtgaagcctgtggcagtggaggagcaggaggcagaagttcccacacaccct
gaggatgtcaccccccagcctggcaacagcaaggtggaggtcgtgttctggcttctatct
atgttggcaacgcgcgaccaggaagatactgcgcgcacgctgctcgccatgtccagctcg
ccagagagctgcgtagccatgcgccgctcgggatgtctgccactgctgctccagatcctt
catggcactgaggctgggtctgtggggcgcacaggaacccccggagcgcctggtgccaaa
gatgcacgcatgcgtgccaacgcggccctgcacaacatagtcttctcccagccggatcag
ggcctggcacgcaaggagatgcgtgtgctgcacgtgctggagcagatccgagcctactgc
gagacctgctgggactggcttcaggcgcgggacagcgggacagagagtggtacaggagac
actcctgtccctatcgagcctcagatctgccaggccgcctgtgcagtgatgaagctgtca
tttgacgaggaataccgtcgggctatgaatgagctaggggggctgcaggctgtggccgag
ctactgcaggtggattatgagatgcacaagatgacccaggatccactcaacctcgccctg
cgccgctacgctggcatgaccctcaccaacctcaccttcggagacgttgccaacaaggcc
actctgtgtgcccgccgaggctgcatggaagccattgtggcccagctggcctctgagagc
gaggagctgcatcaggttgtttccagtattctgcgtaacctgtcgtggagggcggacatc
aacagcaagaaggtgctgagggaggttggcagcatgaccgctttgatggaatgtgtgctg
cgggcctccaaggagtccactctaaagagcgtgctcagtgctctgtggaacctgtcggca
cacagcacagagaacaaggcagctatctgccaggtggatggcgcgctgggtttcctggtg
agcaccctaacataccgttgccaagggaactccctagcagtcatcgagagtggcggtggg
atcctgcgcaacgtgtcaagcctcattgccacgcgggaggactacaggcaggtgctccgt
gaccacaactgcctacagacactgctgcagcacctcacgtcgcacagcttgactatcgtg
agcaatgcctgcggcaccctttggaacctgtctgcccgcagcccccgcgaccaggaactg
ttgtgggacctgggggctgtgggcatgctacgaaacctcgtccactccaaacacaagatg
atcgccatgggtagcgctgccgctctgcggaacctgctggcccaccgaccggccaagtat
caggccgcagccatggcagtctccccaggcacctgcgtgcccagtctgtacgtccgcaag
cagagggccctggaggccgagctggacactcggcacctggtgcatgcgctcggtcacttg
gagaagcagggtctgcctgaggcagagaccacttcaaagaagcccctgccacccctccgc
cacctggacgggctggtgcaggactatgcctctgattctggctgctttgatgatgatgat
gcaccatccctggctgctgcggccaccacagctgagcccgccagcccagcagtgatgtct
atgttccttggtggtcccttccttcagggccaggcactggcccgcaccccacctgcccgc
cagggtggcctagaagctgagaaggagactggtggggaggcagctgtggctgctaaagcc
aaggccaagctagcgttggctgtggctcgcatcgaccgactggtggaggacatctctgcc
ctgcacacctcatcagacgacagcttcagtctcagctcgggggacccggggcaggaggcg
ccaagggagggccgtgcgcagtcctgctctccatgccggggcacagagggtgggcggcgt
gaggctggcagccgggcgcaccctctgctgaggctcaaggcggcccacaccagcctctcc
aacgacagcctgaacagtggtagcaccagcgatggctactgtacccgggaacacatgacg
ccttgcccactggccgtgttgaccgagcaccgcgatggcccagtatgcggacagactcgg
cccagccgactggacctagaccttcccagccgggctgagcttcctgcccgggacacagca
gccactgatgcccgagtgcgcaccattaagttatccccaacctatcagcacgtgccactg
cttgatggggccccgggggcaggtgtcagacccctggttgggcttggaacctccccgggg
actcggaaacaggcatggatacctgcagatagtttgagtaaagtccccgagaagctggtg
gcctccccactgccggtgactagcaaggtgctgcagaagctggtggcacaggatgggccg
atgtccctctccaggtgcagttccctgtcttctctgtcttccacgggccatgcagtcccc
agccaggtggagaaccttgatgacagcgattcatccctggaagagcttgaggaggctggt
cctggcgaggccgagctagacagggcgtggagagcatccgggtccacctctcttccggtg
tccatcccggccccacagcggggtcgaagtcgaggtcttggggtggaggatgctacacca
tccagttcatctgagaactgcgtccaggagacacccttggtcctgagccgctgtagctct
gtgagctccctgggcagcttcgagagccgttccatcgccagctccatcccgagcgacccc
tgcagtgcgctgggcagtggtacagtgagtcccagcgagctgccagacagccccggccag
acaatgccacccagccgcagcaggactccaccggcacctcccgggcagcccgaggccagc
cagttcagcctgcagtgggaaagttacgtgaagcgcttcctggacatcgcagactgtcgg
gaaagatgccagccgccctcggagctggacgcgggcagcgtacgcttcacggtggagaag
ccggacgagaatttctcttgtgcttccagcctcagcgcactggccctgcatgagctgtat
gtccagcaggacgtggaactgcggctgaggccaccagcctgtccagaacgtgcggtgggt
ggtggtgggggccaccgtcggagggacgaggctaccagccgcctggatggcccagcacca
gctggctctagggctcggtcagcggctgataaagaactagaggcgctgcgtgaatgtctg
ggggcagccatgccggcccggctccgcaaggtggcctcggccttggtgcctggccgccgt
gcactgccggtccccgtgtacatgttagtgcccgccccggctcggggtgatgactcgggc
acagactctgcagagggcacgcctgtcaacttttccagtgcagcctctctcagtgacgag
accttacagggaccctccagggataagccggccaggcctggggacaggcagaaacctaca
ggccgagctgctcctgccaggcagacccgtgggcaccggcccaaggcagcaggagcaggt
gctggtaagagcacagagcacacacggggggctaataggaaccgggcaggattggaacta
cccctcagccggccccagagtgctcggtccaacagggatggctcatgccagacccggacc
cgtggagacggtgccctgcagtcgctatgcctcacgacacccacagaggaagctgtgtac
tgcttctatgactctgacgaggagccaccagccacagcaccaccaactcggcgggcgtcc
gccatccctcgggctcttaaacgtgagaaacccgcaggcaggaaagagaccccaaccagg
gcgacacagcctgccacactccctgtgagggcgcagccgagactgatagtagatgagacc
ccaccctgctattccctgacttcctcggctagttccctcagcgagcctgaggcctctgaa
cagccagcctgccaccctcgagtggaggagcagggcagtaaacaagatagtagcccaagg
gcagaagaggagctcctgcagagatgtatcagtttagctatgcccaggcgccggacccag
gtacccagctcacggcgtcgcaagcccagagctgtgaggtcagacataaggcccactgag
ttaccacagaaatgccgtgaagaggttcctggttctgatccagcctctgacctagatagc
gtcgagtggcaggctatccaagagggcgcaaactccattgtcacgtggctgcatcaggca
gcggccaaagccagcctggaagcttcttctgagtctgactccctcttgtctttggtgtct
gggctgtcagcaagctccaccctccagccctccaagctcagaaaagggcgaaagccagtg
gctgaggctgggggtgcctggcgtcctgagaaacggggcacaacttccactaagggcagt
gggagtccccggtttcctagtggccctgagaaggcaaagggtacccagaaaacgatggca
ggggagtcagccatgctccggggaaggacagtgatctacactgccagccctgcttcccgg
gctcagtccaaaggtatttctggaccttgttccgcacctaagaagatggggacatctggt
accactcagccagaaactgccaccaaaacccccagccctgagcaacaacgttctcggagc
ctgcaccgaccaggcaagatctctgagttggcagccttgagccacccgcccaggagtgct
actcctccagcccgcctcaccaagaccccgtcttcaagctcttcacagacctccccggca
tcccagtccctgcctaggcggtccccactggccactccaacaggagggcctctgcctgga
cctggggggtccccggtgcccaagtcaccagcccgggctcttctggctaagcaacacaag
acccagaagtcacccgtgcgtatcccattcatgcaaaggccagccaggcgagtgccacct
ccactggccaggccatccccagagcctggctccaggggccgagctggggctgagggaact
cctggggcacgtggcagccgcctgggcctggtacgtgtggcctcaactcgctctagcggc
agtgagtcctcagaccgctccggcttcagaaggcagctgaccttcattaaggagtcccca
ggtctcctccggcgccgtagatcggagctgtcctctgcggactccacggtctccacctcc
cagaccgcttcgccctgccgcggacggcccgcactccccgctgtctttctctgctcctct
cgctgtgatgagctgcgagcgtctccacggcagcccctggcagcacagagggtcccgcag
gccaagccaggtcttgccccacgtgcgcccagacgcaccagctccgagagcccctcacgc
ctgcctgtacgggcgacccctgggcggcccgagacagtcaagaggtacgcctccctgcca
catattagtgtgtcccgcaggcccgatagcgctgtctctgtgcccaccacccaggccaat
gccactcgcaggggaagtgatggcgaggccaggccgctgcccagggtggctgcgccgggt
acgacctggcgtcgtatcaaagatgaagatgtcccccacatcctgcgcagcacactgccg
gccactgccctgcctctcaggggctcatcacccgaagacagtcctgctggaactccacac
cgcaagactagcgacgcagtggtacagacagaggatgtggccacctctaaaaccaactcc
agcacgtcgcccagcctggagagcagggatcccccacaggccccgatcagtggccctgtt
gctccactgggcagcgatgtggatggaccagtacttgccaagcctcctgcctcagcgccc
ttcacccatgagggtctgagtgttgtcacggggggctttcctactagcaggcatggctcc
cccagtagggctgcacgggttccccccttcaactacgtgcccagccctatggtagtggct
acaatgaccagtgactcagctgtggagaaagcccctgttacctctccagccagcctcctg
gagtag

All links

Pathway (6)   
   KEGG PATHWAY (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
   UNIGENE (1)   
   ENSEMBL-RNO (1)   
   RATMAP-RNO (1)   
   RGD-RNO (1)   
Protein sequence (4)   
   RefSeq(pep) (3)   
   IPI (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (12)   
   Pfam (8)   
   PROSITE (4)   
All databases (34)

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