KEGG   Rattus norvegicus (rat): 301348Help
Entry
301348            CDS       R.norvegicus                           
Gene name Zap70
Definition zeta-chain (TCR) associated protein kinase (EC:2.7.10.2)
Orthology K07360  zeta-chain (TCR) associated protein kinase [EC:2.7.10.2]
Pathway rno04650  Natural killer cell mediated cytotoxicity
rno04660  T cell receptor signaling pathway
rno05340  Primary immunodeficiency
Class Metabolism; Enzyme Families; Protein kinases
Environmental Information Processing; Signaling Molecules and
Interaction; Cellular antigens
Organismal Systems; Immune System; Natural killer cell mediated
cytotoxicity [PATH:rno04650]
Organismal Systems; Immune System; T cell receptor signaling pathway
[PATH:rno04660]
Human Diseases; Immune System Diseases; Primary immunodeficiency
[PATH:rno05340]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: Pkinase_Tyr Pkinase SH2 RIO1 Kdo Ribosomal_S27
PROSITE: PROTEIN_KINASE_TYR PROTEIN_KINASE_ATP SH2
         PROTEIN_KINASE_DOM
Motif
Other DBs NCBI-GI: 58865580
NCBI-GeneID: 301348
RGD: 3983
RATMAP: ENSRNOG00000016995
Ensembl: ENSRNOG00000016995
UniProt: Q5FVN9
Position 9q21
AA seq 614 aa AA seqDB search
MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFP
IERQLNGTYAIAGGKAHCGPAELCQFYSQDPDGLPCNLRKPCNRPPGLEPQPGVFDCLRD
AMVRDYVRQTWKLEGDALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSG
QQTDGKFLLRPRKEQGTYALSLVYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLK
LKADGLIYRLKEVCPNSSASAEAAAPTLPAHPSTFTQPHRRIDTLNSDGYTPEPARLDKP
RPMPMDTSVYESPYSDPEELKDKKLFLKRENLLVADIELGCGNFGSVRQGVYRMRKKQID
VAIKVLKQSTEKADKDEMMREAQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKF
LIGKKEEIPVSNVAELLHQVAMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKA
LGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEAFSYGQKPYKKMKG
PEVLDFIKQGKRMECPPECPPEMYALMSDCWIYKWEDRPDFVAVEQRMRTYYYSMASRAE
GPPQCEQVAEAACG
NT seq 1845 nt NT seq  +upstreamnt  +downstreamnt
atgcccgaccccgcggcgcatctgccattcttctacggaagcatttcgcgggccgaggcc
gaggagcacctgaagctggcaggcatggccgacggactgttcctcctgcgccagtgcctg
cgctcgctgggcggctacgtgctgtcgctagtacacgacgtgcgcttccaccatttcccc
atcgagcgccaactcaatggcacgtacgccatcgcgggcggcaaggcgcactgcggcccg
gccgagctctgccagttctactcgcaggaccccgacggactgccctgcaatctgcgtaag
ccatgcaaccggccgccgggacttgagcctcagcccggggtcttcgactgcctgcgcgat
gctatggtgcgggactacgtgcgccagacctggaaactggagggtgatgcactagagcag
gccatcatcagccaggccccacaggtggagaagctcattgctaccacagcccacgagcga
atgccctggtaccacagcagcctgactcgcgaggaggctgagcgcaaactctattctggc
cagcagaccgacggcaagttcctgctgagaccccggaaggagcagggcacatatgcgctg
tccctggtctacgggaaaactgtgtaccactatctcatcagccaggacaaggctggcaag
tactgtatccccgaaggcaccaagtttgatacgctctggcagctggtggagtacctgaag
ctgaaggcagatggactcatttatcgcctgaaggaggtctgtcccaacagcagtgccagc
gccgaagctgctgcacccacgctcccagcccacccatccacattcactcagcctcacaga
cgaattgataccctgaactcagacggatacacccctgaaccagcacgcttagacaagcca
cgaccgatgcccatggacacgagcgtgtacgagagcccctacagcgaccccgaggaactc
aaggacaagaagctcttcctgaagcgagagaacctcctcgtggccgacatcgaacttggt
tgcggcaactttggctcagtgcgccagggagtctaccgcatgcgcaagaagcagatcgac
gtggccatcaaggtgctaaagcagagcacagagaaagctgacaaggatgagatgatgcgg
gaggcccagatcatgcatcagctcgacaacccctacattgtgcggctcatcggcgtgtgc
caggcagaggcgctcatgctggtcatggagatggcaggaggcgggccactgcacaagttc
ctgattggaaaaaaggaggagatcccggtgagcaacgtggctgaactgctgcaccaggtg
gccatgggcatgaagtatttggaggagaagaactttgtgcaccgtgacctggcagcccgg
aatgttctactggtcaatcggcactatgccaagatcagcgactttggcctgtccaaggca
ctgggtgctgatgacagctattacacagcccgttctgcagggaagtggcctctgaagtgg
tacgcaccagaatgcatcaacttccggaagttctccagccgcagtgatgtctggagctat
ggggtcaccatgtgggaggccttctcctatggccagaagccctacaagaagatgaagggc
cctgaggtcctggatttcatcaagcagggtaagaggatggaatgccctccagagtgtccg
cccgaaatgtacgcgcttatgagtgactgctggatatacaagtgggaggatcgtcccgat
ttcgtggctgtggaacaacgaatgaggacctattactacagcatggctagccgggcagag
ggacccccacagtgtgaacaggtggccgaggctgcatgtggctga
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