KEGG   Rattus norvegicus (rat): 303200Help
Entry
303200            CDS       T01003                                 

Gene name
Map2k3, Mek3, Mkk3
Definition
mitogen activated protein kinase kinase 3
Orthology
K04432  
mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
MAPK signaling pathway
Rap1 signaling pathway
Toll-like receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Amyotrophic lateral sclerosis (ALS)
Toxoplasmosis
Influenza A
Epstein-Barr virus infection
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    303200 (Map2k3)
   04010 MAPK signaling pathway
    303200 (Map2k3)
   04668 TNF signaling pathway
    303200 (Map2k3)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    303200 (Map2k3)
   04664 Fc epsilon RI signaling pathway
    303200 (Map2k3)
  Endocrine system
   04912 GnRH signaling pathway
    303200 (Map2k3)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    303200 (Map2k3)
 Human Diseases
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    303200 (Map2k3)
  Infectious diseases
   05164 Influenza A
    303200 (Map2k3)
   05169 Epstein-Barr virus infection
    303200 (Map2k3)
   05145 Toxoplasmosis
    303200 (Map2k3)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     303200 (Map2k3)
Protein kinases [BR:rno01001]
 Serine/threonine protein kinases: STE group
  STE7 family
   303200 (Map2k3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
UniProt: 
Position
10q22
AA seq 347 aa AA seqDB search
MESPAASPPASLPQTKGKSKRKRDLRISCVSKPPVSNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLEKNMKIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADQFSPEFVD
FTSQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt NT seq  +upstreamnt  +downstreamnt
atggagtcgcccgccgccagcccgccggccagcttgcctcagaccaaaggaaaatccaaa
aggaaaagggatttacggatatcctgtgtgtccaagccacccgtgtccaaccccacaccc
ccccggaacctggactcccggaccttcatcactatcggagacagaaacttcgaagtggag
gctgatgacttggtgaccatctcagagctgggccgcggagcctatggggtggtggagaag
gtgcggcatgctcagagtggtaccatcatggctgtcaagcgcatccgggccactgtgaac
tcacaggagcagaaacgtctgcttatggacctagacatcaacatgcgcactgtcgactgc
ttctatactgtcaccttctatggtgccctctttagagagggggatgtgtggatctgcatg
gaactcatggacacgtccctggataagttctaccggaaggtgctagagaagaacatgaaa
attccggaagacattctgggggagattgctgtatccatcgtgcgggccctggagcaccta
cacagcaagctgtctgtgatccacagagatgtgaagccttccaatgtcctcatcaacaaa
gaggggcacgtgaagatgtgcgactttggcatcagtggctacctggtggactctgtggca
aagacaatggatgctggctgcaagccttacatggcccctgagaggatcaaccctgagctg
aatcagaagggctacaacgtcaagtctgatgtctggagccttggcatcaccatgattgag
atggccattctgcgattcccttacgagtcttgggggacaccgttccagcagctgaagcag
gtggtggaggagccatccccacagctcccagcagaccagttctcccctgagtttgtggac
ttcacaagccagtgcctcaggaagaatcctgcggaacgcatgagctacctggagctgatg
gaacacccgttcttcaccttgcacaaaactaagaagacggacattgctgcctttgtgaag
gagatcctgggagaggattcatag

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