KEGG R.norvegicus: 311450

Rattus norvegicus (rat): 311450

Entry

311450 CDS R.norvegicus

Gene name Pak7

Definition p21 protein (Cdc42/Rac)-activated kinase 7 (EC:2.7.11.1)

Orthology K05736 p21-activated kinase 7 [EC:2.7.11.1]

Pathway rno04012 ErbB signaling pathway
rno04360 Axon guidance
rno04510 Focal adhesion
rno04660 T cell receptor signaling pathway
rno04810 Regulation of actin cytoskeleton
rno05211 Renal cell carcinoma

Class Metabolism; Enzyme Families; Protein kinases
Environmental Information Processing; Signal Transduction; ErbB
signaling pathway [PATH:rno04012]
Cellular Processes; Cell Motility; Regulation of actin cytoskeleton
[PATH:rno04810]
Cellular Processes; Cell Communication; Focal adhesion
[PATH:rno04510]
Organismal Systems; Immune System; T cell receptor signaling pathway
[PATH:rno04660]
Organismal Systems; Development; Axon guidance [PATH:rno04360]
Human Diseases; Cancers; Renal cell carcinoma [PATH:rno05211]

SSDB

Motif Pfam: Pkinase Pkinase_Tyr PBD APH
PROSITE: PROTEIN_KINASE_ATP SER_RICH CRIB PROTEIN_KINASE_DOM

Other DBs NCBI-GI: 157821269
NCBI-GeneID: 311450
RGD: 1312009
RATMAP: ENSRNOG00000005509
Ensembl: ENSRNOG00000005509

Position 3q36

AA seq 718 aa
MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT
PIQLAPMKTIVRGNKSCKESSINGLLEDFDNISVTRSNSLRKESPPTPDQGAASRIQGHS
EENGFITFSQYSSESDTTTDYTTEKYRDRSLYGDDLDLYYRGSHAAKQNGHAMKMKHGDA
YYPEMKPLKSDLARFPVDYHTHLDSLSKASEYGDLKWDYQRASSSSPLDYSFQLTPSRTA
GTSRCSKESLAYSESDWGPSFDDYDRRPKSSYLHQTSPQPAMRQRSKSGSGLQEPMMPFG
ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVFSPPLSGSDTYPRGPTKLPQS
QSKVGYSSSSHQYPGYHKASLYHHPSLQTSSQYISTASYLSSLSISSSTYPPPSWGSSSD
QQPSRVSHEQFRAALQLVVSPGDPREYLDNFIKIGEGSTGIVCIATEKHTGKQVAVKKMD
LRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMN
EEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRK
SLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPP
RVKDLHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH

NT seq 2157 nt +upstreamnt +downstreamnt
atgtttgggaagaaaaagaaaaagatcgaaatatccggcccatctaactttgaacacagg
gttcatactgggtttgatccacaagagcagaagtttactggccttccccagcagtggcac
agcctgttagcagacacagccaacaggcccaagcctatggtggatccatcatgcatcaca
cccatacaactggctcccatgaagacaatcgtcagaggaaataaatcctgcaaggaaagc
tctatcaacggtctgctagaggatttcgacaacatctccgtgactcgctccaactcccta
aggaaagaaagcccacccaccccagatcagggagcagctagccgcattcaaggccactcc
gaagaaaacggcttcattactttctcacaatattctagtgaatctgatactactacggac
tacacaactgaaaagtatagagacaggagtctctatggagacgacctggatctgtactat
agaggcagccatgcagccaagcaaaacgggcatgctatgaagatgaaacatggagatgcc
tactatcctgagatgaagcctttgaaatccgacctggccagattccctgtcgactatcac
acacacttggactcgctgagcaaagcaagtgagtacggtgacctcaagtgggattatcag
cgagcctccagtagctcccctctggactactcattccagctcacgccttccagaactgca
gggaccagcaggtgctccaaggagagtctggcatacagtgaaagtgattggggacccagc
tttgatgactatgataggaggccaaaatcatcctacctgcatcagacaagccctcagcca
gccatgcgccagagatccaagtcaggctcagggcttcaggaacccatgatgccatttgga
gcaagtgcatttaaaactcatcctcaaggacactcgtacaactcctacacctaccctcga
ttgtctgagcccacaatgtgcattccaaaggtggattatgatcgagcacagatggtcttc
agtcctccactgtcagggtccgacacctatcccagaggccccaccaaactacctcaaagt
caaagcaaagtgggctactcttcaagtagccaccagtatcctgggtaccacaaagcatcc
ctataccatcatccgtccctgcaaaccagttctcagtacatctccaccgcttcttacttg
agctctctcagtatctcctcgagcacctaccctccacccagctggggctcctcttcagac
cagcagccctctagggtatcccatgaacagtttcgagctgccctgcaactggtggtcagc
ccaggagaccccagggaatatttggataactttattaaaatcggagaagggtcgacaggc
atcgtgtgcattgcaacagagaagcacacaggcaagcaagtggcggtgaagaaaatggac
ctccgaaagcaacagagacgggaactcctttttaatgaggtcgtgataatgcgtgattac
caccatgacaatgtagttgacatgtataacagctaccttgttggagatgagctctgggtg
gtcatggagtttctagaaggtggtgccttgacagacatcgtcactcataccagaatgaat
gaagaacagatagctactgtctgcctgtcagttctgaaagcgctgtcctaccttcataac
caaggagtgattcacagggacataaagagtgactccattcttctgacaagcgatggccgg
ataaagttatctgactttggcttctgtgctcaagtttccaaagaggtgccaaagaggaag
tcactggtgggtaccccatactggatggctcctgaggtgatttccaggctaccttatggg
acagaggtggacatctggtccctcgggataatggtgatagagatgattgatggtgagcct
ccctatttcaatgagcctcctctgcaggccatgaggaggatccgggacagtttacctcca
agagtgaaggacctgcacaaggtttcttccatgctccgaggattcctagatcttatgttg
gtgagggagccctctcaaagagccacagctcaagaacttcttggacatccattcttaaaa
ttggcaggcccgccatcttgcatcgttcccctcatgagacaatataggcatcactga

All links

Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
   UNIGENE (1)   
   ENSEMBL-RNO (1)   
   RATMAP-RNO (1)   
   RGD-RNO (1)   
Protein sequence (5)   
   RefSeq(pep) (3)   
   IPI (2)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (8)   
   Pfam (4)   
   PROSITE (4)   
All databases (32)

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