KEGG   Rattus norvegicus (rat): 313845Help
Entry
313845            CDS       T01003                                 

Gene name
Sos1
Definition
Son of sevenless homolog 1 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
rno  Rattus norvegicus (rat)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    313845 (Sos1)
   04010 MAPK signaling pathway
    313845 (Sos1)
   04012 ErbB signaling pathway
    313845 (Sos1)
   04630 Jak-STAT signaling pathway
    313845 (Sos1)
   04068 FoxO signaling pathway
    313845 (Sos1)
   04151 PI3K-Akt signaling pathway
    313845 (Sos1)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    313845 (Sos1)
  Cellular commiunity
   04510 Focal adhesion
    313845 (Sos1)
   04540 Gap junction
    313845 (Sos1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    313845 (Sos1)
   04660 T cell receptor signaling pathway
    313845 (Sos1)
   04662 B cell receptor signaling pathway
    313845 (Sos1)
   04664 Fc epsilon RI signaling pathway
    313845 (Sos1)
   04062 Chemokine signaling pathway
    313845 (Sos1)
  Endocrine system
   04910 Insulin signaling pathway
    313845 (Sos1)
   04912 GnRH signaling pathway
    313845 (Sos1)
   04915 Estrogen signaling pathway
    313845 (Sos1)
   04917 Prolactin signaling pathway
    313845 (Sos1)
  Nervous system
   04722 Neurotrophin signaling pathway
    313845 (Sos1)
  Development
   04320 Dorso-ventral axis formation
    313845 (Sos1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    313845 (Sos1)
   05206 MicroRNAs in cancer
    313845 (Sos1)
   05205 Proteoglycans in cancer
    313845 (Sos1)
   05214 Glioma
    313845 (Sos1)
   05221 Acute myeloid leukemia
    313845 (Sos1)
   05220 Chronic myeloid leukemia
    313845 (Sos1)
   05211 Renal cell carcinoma
    313845 (Sos1)
   05215 Prostate cancer
    313845 (Sos1)
   05213 Endometrial cancer
    313845 (Sos1)
   05223 Non-small cell lung cancer
    313845 (Sos1)
  Substance dependence
   05034 Alcoholism
    313845 (Sos1)
  Infectious diseases
   05160 Hepatitis C
    313845 (Sos1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
6q11
AA seq 1319 aa AA seqDB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNEDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPAERIHHLLREVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSSY
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DVLRPGFHERFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECMKQAITALLNVQSGMEKICSKNLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDGNSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEHMRLPSADVYRFAEPDSEENILFEENVQPKAGIPI
IKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLNLLIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDVDLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQNSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLRRHGKELINFSK
RRRVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASSASSNTDVCSVFDSDHSASPFHSRSASVSSISLSKGTEEVPVPPPVP
PRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLL
PPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLP
SPPLTQEVDLHSIAGPPVPPRQSTSQLIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
NT seq 3960 nt NT seq  +upstreamnt  +downstreamnt
atgcaggcgcagcagctgccctacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctggtgcctgcgctgaaaaaggttcaggggcaagttcaccctactcttgagtct
aatgaggatgctcttcagtatgttgaagaattaattttgcaattactaaatatgctatgc
caagctcagccccggagtgcttcagatgtggaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccaatcagctattgaaaagaggaagagaagg
aaccctttatccctgccagcagaaagaattcatcatttattaagggaggtcctgggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagat
attttaaagctggtggggaattatgtaagaaatatacggcattatgaaattacaaaacaa
gacattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatcttatctttaactgatgaagaaccttccacctcaggagaacaaact
tactatgatttggtaaaagcattcatggcagaaattcgacaatatataagagaattaaat
ctaattataaaggtttttcgagaaccctttgtctctaattccaagttgttttcatcttat
gatgtagaaaacatatttagtcgtatagtggatatccatgaacttagtgtaaagttactg
ggccatatagaagacactgtagagatgacagatgaaggcagtccccacccgttagtcgga
agctgttttgaagacttagcagaagaactggcctttgacccatatgagtcctatgctcgg
gatgttctgcggcccggattccatgagcgttttctcagtcagctatcaaagcctggggca
gcactttatctgcagtccataggtgaaggcttcaaagaggccgttcagtatgtcctgccc
cggctgctgctcgcccctgtgtaccactgtctgcattactttgaacttctgaagcagtta
gaagaaaagagcgaagatcaagaagataaggagtgtatgaaacaagcaataacagccctg
cttaatgtccaaagtggcatggaaaaaatttgctccaaaaatcttgcaaaacgaagactg
agtgagtctgcatgtcggttttacagccagcaaatgaaggggaaacaactggccatcaag
aagatgaatgagattcagaagaacattgatggttgggaggggaaagacattggacaatgc
tgcaatgagtttataatggaaggaactcttacacgtgtaggagccaaacacgagagacac
atatttctcttcgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggtgctagcaatgcagaatatcggcttaaagaaaagttttttatgcgaaaggtacag
attaacgataaggatgacaccagtgaatacaagcacgctttcgaaataattctgaaggat
ggaaatagtgttatattttctgccaagtcagctgaagagaagaataactggatggcagcc
ctgatatccctgcagtaccgcagcacgctggagagaatgctggacgttacaatgctgcag
gaggagaaggaggagcacatgaggctgccgagtgctgacgtgtacaggtttgcagagccc
gactctgaggagaacattctgtttgaagagaacgtgcagcccaaggctggcatccccatc
atcaaggcagggacagtggttaagctgattgagaggctcacgtaccacatgtacgcagat
ccaaattttgttcggacatttcttacaacatacagatcattttgcaaacctcaagaacta
ctgaatcttctaatagaaagatttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcagcccctgagcgcagagctgaaaaggtttagaaaggag
tatatccagcctgtacagctgagggtgttaaacgtgtgtcggcactgggtggagcaccat
ttctatgactttgaaagagatgtagaccttttacagagaatggaggaatttattggaaca
gtaagaggtaaagcaatgaaaaaatgggtcgaatccatcactaagataatccaaaggaaa
aaaattgcaagagacaatggcccaggtcataatattacatttcagaattcacctcccaca
gttgagtggcacataagcagacctgggcatatagagacttttgacttgctcaccctacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctataccgagctgtgcag
ccatcagaattagttggaagtgtgtggacaaaagaagataaagaaattaactctcctaac
cttctgaaaatgattcggcacaccaccaacctcactctgtggtttgagaaatgtattgta
gaaacagagaacttagaagaaagagtagcagtagtgagtcgaataattgagattctacaa
gtctttcaagagctgaacaacttcaatggtgtcctggaagttgttagtgctatgaactcg
tcacctgtttacagactggaccacacatttgagcaaataccaagtagacaaaagaaaatt
ttagaagaagctcatgagttgagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctcacaaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaagaagacatggaaaagagcttatcaacttcagcaag
aggaggagagtggccgagataacaggagagatccagcagtaccaaaaccagccttactgc
ttacgggtagagtcagacatcaagagattctttgaaaacttgaatccaatgggaaatagc
atggagaaggaatttacagactatctattcaacaaatccctagaaatagaaccacggaac
cctaagcctcttccaagatttccaaaaaaatacagctatcccctaaaatctcctggtgtt
cgtccatcaaatccaagaccaggaaccatgaggcaccctacacctctgcagcaggagcca
aggaaaatcagctacagtcggattcctgagagcgagacagaaagtacagcgtcggcacca
aactccccgagaacaccgctgacgccgcctcctgcgtccagcgcctccagtaacacagac
gtctgcagcgtgttcgattccgaccactccgcaagcccttttcactcaagatctgcttca
gtctcatctataagtttatccaagggcaccgaggaagtgcctgtccctcctcctgtcccc
cctcgaagacgaccagagtctgccccagcggaatcctccccatccaagattatgtctaag
cacttggatagccccccagcgattcctcctaggcagcccacatcgaaagcctattcacca
cgatactcaatatcagatcggacctctatatcagatcctcccgagagccctcccttgtta
ccaccacgagaacctgtgaggacacccgatgttttctcaagctcgccattacatctccaa
cctcccccgttgggcaaaaagagtgaccatggcaatgccttcttcccaaacagcccatcc
ccctttacaccgccacctcctcaaaccccgtctcctcacggcacgagaaggcatctgcca
tcaccaccactgacacaggaagtggacctccattccattgctgggcctcccgttcctcca
cggcaaagcacttctcaacttatccccaaactccctccaaaaacttacaaaagggagcac
acacacccatccatgcacagagatggaccgccactgctggagaatgcccattcttcctga

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