KEGG R.norvegicus: 363577

Rattus norvegicus (rat): 363577

Entry

363577 CDS R.norvegicus

Gene name Itk

Definition IL2-inducible T-cell kinase (EC:2.7.10.1)

Orthology K07363 IL2-inducible T-cell kinase [EC:2.7.10.2]

Pathway rno04062 Chemokine signaling pathway
rno04660 T cell receptor signaling pathway
rno04670 Leukocyte transendothelial migration

Class Metabolism; Enzyme Families; Protein kinases
Organismal Systems; Immune System; T cell receptor signaling pathway
[PATH:rno04660]
Organismal Systems; Immune System; Leukocyte transendothelial
migration [PATH:rno04670]
Organismal Systems; Immune System; Chemokine signaling pathway
[PATH:rno04062]

SSDB

Motif Pfam: Pkinase_Tyr Pkinase SH2 BTK SH3_1 PH SH3_2 APH
PROSITE: PROTEIN_KINASE_TYR PROTEIN_KINASE_ATP PH_DOMAIN SH2 SH3
ZF_BTK PROTEIN_KINASE_DOM

Other DBs NCBI-GI: 157818821
NCBI-GeneID: 363577
RGD: 1311618
RATMAP: ENSRNOG00000006860
Ensembl: ENSRNOG00000006860

Position 10q21

AA seq 626 aa
MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRI
KCVEIVKSDISIPCHYKYPFQTLTSFQVMHDNYLLYVFAPDCESRQRWVLTLKEETRNNN
SLVSKYHPNFWMDGRWRCCSQLEKLAVGCAPYDPTKNASKKPLPPTPEDNRRSFQEPEET
LVIALYDYQTNDPQELALRRDEEYYLLDSSEIHWWRVQDKNGHEGYAPSSYLVEKSPNSL
ETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISENNPCIKHYH
IKETNDSPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCSWRQKAPVTAGLRYG
KWVIQPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMKLS
HPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAYLE
KACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSR
YSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASPHVYQVMNHC
WKEKPEDRPPFSRLLSQLAEIAECGL

NT seq 1881 nt +upstreamnt +downstreamnt
atgaacaacttcatcctcctggaagaacagctgatcaagaagtcccaacagaagagaagg
acttctccctcgaattttaaagtccgtttcttcgtcttaacgaaagccagcctggcatac
ttcgaggaccgccacgggaagaagcgcacgttgaagggctccatcgaactctccagaatc
aagtgcgtggagattgtcaagagtgacattagcatcccgtgccactataaataccctttt
cagactcttacgtccttccaggtcatgcacgacaactacctcctgtacgtgtttgctcca
gactgcgagagccgtcagcgctgggtgctcacccttaaagaagaaacgaggaataacaac
agcctagtatccaagtatcaccctaatttctggatggatgggcggtggaggtgctgttcc
cagctagagaagcttgccgtaggctgtgctccctacgacccaacgaagaatgcttcaaag
aagcctcttcctcctactcctgaagacaacaggcggtcatttcaggaacctgaagaaacc
ctggtcattgccttgtacgactaccaaaccaacgatcctcaggagctcgcgctgcggcgt
gatgaagagtactacctgctggacagctccgagatccactggtggcgggttcaagacaag
aatgggcatgaaggatatgcacccagcagttacctggtggaaaagtctccaaatagcctt
gaaacctacgagtggtacaataaaagcatcagccgagacaaagctgaaaaacttcttttg
gacacaggtaaagaaggagcattcatggtccgagattccaggacacccgggacatacaca
gtctctgtcttcaccaaggccatcataagtgagaacaacccctgtataaaacattatcac
atcaaagaaacaaatgacagccccaagcggtactatgtggctgagaagtatgtgtttgac
tccatccctctcctcatccagtatcaccaatacaatggaggaggtttggtcactcgactc
cggtatccagtttgctcctggaggcagaaagcccctgtcacagcagggctaagatatggg
aagtgggtgatccagccctcggagctaactttcgtgcaggagattggcagcgggcagttt
ggactggtgcatctcggctactggctcaacaaggacaaggtggccatcaagaccattcag
gaaggggcgatgtcagaagaagactttatcgaggaggcagaagtcatgatgaaactctct
caccccaagctggtgcagctctatggggtgtgcttggagcaagcccccatctgcctggtg
tttgagttcatggagcacggctgcctatcggattaccttcgaagtcagcggggtctcttt
gctgcagagaccctgctgggcatgtgcctggacgtgtgtgagggcatggcctacctagaa
aaagcgtgtgtcatccacagagacctggccgccaggaactgtttggtgggagaaaaccag
gtcatcaaggtgtccgacttcggcatgacaaggtttgtccttgatgatcaatataccagc
tccacgggcaccaaattcccagtgaagtgggcatccccagaagtgttctccttcagccgc
tacagcagcaagtcagatgtgtggtcatttggtgtactgatgtgggaagtcttcagcgaa
ggcaaaatcccatatgaaaaccgaagcaattcagaggtcgtggaagacatcagcactggc
tttcggttatacaagccccgcctggcctcccctcatgtctaccaggtcatgaatcactgc
tggaaagagaaaccggaagaccggccacccttctcccggctgttaagccaactggctgaa
atcgcagaatgtggactttag

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
   UNIGENE (1)   
   ENSEMBL-RNO (1)   
   RATMAP-RNO (1)   
   RGD-RNO (1)   
Protein sequence (6)   
   RefSeq(pep) (4)   
   IPI (2)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (15)   
   Pfam (8)   
   PROSITE (7)   
All databases (37)

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