KEGG T01003: 364786

Rattus norvegicus (rat): 364786

Entry

364786 CDS T01003

Gene name

Itga8, RGD1564327

Definition

integrin, alpha 8

Orthology

K06584

integrin alpha 8

Organism

rno Rattus norvegicus (rat)

Pathway

rno04151	PI3K-Akt signaling pathway
rno04510	Focal adhesion
rno04512	ECM-receptor interaction
rno04514	Cell adhesion molecules (CAMs)
rno04810	Regulation of actin cytoskeleton
rno05410	Hypertrophic cardiomyopathy (HCM)
rno05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
rno05414	Dilated cardiomyopathy

Class

Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:rno04151]
Environmental Information Processing; Signaling molecules and interaction; ECM-receptor interaction [PATH:rno04512]
Environmental Information Processing; Signaling molecules and interaction; Cell adhesion molecules (CAMs) [PATH:rno04514]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:rno04810]
Cellular Processes; Cell communication; Focal adhesion [PATH:rno04510]
Human Diseases; Cardiovascular diseases; Hypertrophic cardiomyopathy (HCM) [PATH:rno05410]
Human Diseases; Cardiovascular diseases; Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:rno05412]
Human Diseases; Cardiovascular diseases; Dilated cardiomyopathy (DCM) [PATH:rno05414]

SSDB

Motif

Pfam:

Integrin_alpha2 FG-GAP VCBS Integrin_alpha

Other DBs

NCBI-GI:

NCBI-GeneID:

RGD:

Ensembl:

UniProt:

Position

17q12.3

AA seq 1062 aa
MSARTHRGPPENWAPPFACLCCVSAVLGMLWSPVSLAFNLDVDKLTVYSGPEGSYFGYSL
DFYIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAERSAQCKQIPFDTTNNRKIRV
NGTKEPIEFKSNQWFGATVRAHKGKVVACAPLYHWRTLKPNPAKDPVGTCYVAIQNFSAY
AEHSPCRNSNVDPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITVSVADIIANYS
FKDILRKLAAEKQTDVAPASYDDSYLGYSVAAGEFTGDSLQELVAGIPRGAQNFGYVSII
NSTDMTFIQNFTGEQMASYFGYTVVVSDVNNDGMDDILVGAPLFMEREFESNPREVGQVY
LYLQVSALLFQDPQVLTGTETFGRFGSSVAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLI
YNGNARGLHSKPSQVLQGIWGSQTIPSGFGFSLRGDADIDKNDYPDLLVGAFGEGKVAVY
RARPVVTVDAQLLLHPMIINLENKTCQIPEFPTPVACFSLRVCASIAGQSISNTVALMAE
VQLDFLKQKGAIKRTLFLHNHQSHLIFPFVMRQQKSLHCQDFMVYLRDETEFRDKLSPIN
VSLNYSLDDSTFEDGLEVKPILNHYRENVVTEQAHILVDCGEDNLCVPDLRLSARPDKQE
IIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGLRLLSCEYKMENVT
RMVVCDLGNPMVTGTNFSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSVQINV
TAVAQVEIRGVSHPPQIVLPIHNWEPAEEPHKEEEVGPLVEHIYELHNIGPSTISDSILE
VGWPFSAREEFLLYVFHLQTLGPLQCQTNPEINPQDIKPAASPEDTPELSAFLRNATIPH
LVRKRDVPVVQPHRQSPAKILNCTNIDCLQISCAVGRLGGGESAVLKVRSRLWAHTFLQR
KNDPYALASLVSFEVKKIPYKEQPAKLPAGSTAIKTSVIWATPNVSFSIPLWVIILAILL
GLLVLAILTLALWKCGFFDRARPPQDEMTDREQLTSDKTPEA

NT seq 3189 nt +upstreamnt +downstreamnt
atgtctgcgagaacccaccggggtcccccggagaactgggcacctccgttcgcttgtctc
tgttgcgtctcggccgtgctggggatgctgtggtcccccgtgtctctggcgttcaacttg
gacgtagacaagctcacggtgtacagtggccccgagggcagctacttcggctactcgctg
gacttctacatacctgatgcgcgcacagccagtgtcttggtgggggcgcccaaagccaac
actagccagccggatatcgtagaagggggagctgtctactactgtccctggcctgcagag
aggtctgcacagtgcaagcagataccctttgacaccaccaacaacaggaaaatcagagtt
aatggaaccaaagagcctatagaatttaaatcaaaccaatggtttggagccacagtgaga
gctcacaaaggaaaagttgtggcttgtgcccctttatatcactggagaactctgaagcct
aatccagcaaaggacccggttggcacatgctatgtagcaattcagaacttcagtgcttac
gctgagcactcaccctgtcggaacagcaacgttgatcctgaaggccaaggttactgccaa
gccggcttcagtctagacttctataagaatggagaccttatagtgggaggacctggaagc
ttttactggcaaggtcaggtgatcacggtcagtgtagcagacatcattgcaaattactca
ttcaaagacattcttcgaaaactggcagcagaaaagcagacagatgtggctccagcttcc
tatgatgacagctaccttggatattcagttgctgctggagaattcactggggactctctg
caagaattggttgctggaattccaagaggagcacagaactttggatatgtctccatcatt
aactccacagatatgaccttcattcagaattttactggtgagcagatggcatcttatttc
ggatatactgttgtggtatcagatgttaacaatgatggcatggatgacatattggtcggg
gcacctctctttatggagcgagaatttgaaagtaaccctagagaagtgggtcaggtctac
ctgtacctacaagtgagcgccctcctcttccaagacccacaggtccttacgggcacagag
acttttgggagattcggtagttctgtggcccacttgggggacctgaaccaagatggatac
aatgatattgccatcggtgtgccctttgcaggcaaggatcaaagaggtaaagtcctcatt
tacaacggaaacgccagaggcttgcacagcaagccttcccaagttctgcaaggaatatgg
gggtcacagaccatcccttctggattcggcttttctctaagaggagacgcagacatagac
aagaatgattacccagatttacttgtcggggcatttggagaagggaaagtggccgtgtac
agagcaaggccagttgtaacagtggatgcccagcttctgctgcacccaatgattatcaac
cttgaaaataaaacttgccagattccagaattcccgactcctgtggcctgcttttcttta
agagtctgtgcatctatagcaggccagagcatttcaaatacagtagccctgatggccgag
gtgcagttagatttcctgaagcaaaaaggagccatcaaacggaccctcttcctccacaac
caccagtcccacctcatcttccccttcgtgatgaggcagcaaaaatccctccactgccag
gattttatggtttaccttcgagatgaaactgaattccgagataaactgtctccaatcaac
gttagcctgaactacagtttggatgattccacctttgaagatggcctggaagtgaagccg
attttgaaccactacagggagaatgtcgttactgagcaggctcacatcctggtggactgt
ggagaagacaacctctgtgttcctgacttgaggctgtcagctagaccagataagcaggag
ataattattggggatgaaaatcacctaatgctcataatcaatgcaaggaatgaaggagaa
ggagcttacgaagctgaactcttcgtcatgattcccgaagaagcagattacgttgggatc
gagcgcaacaacaagggactgaggctcctgagttgtgagtacaagatggaaaacgtaacc
aggatggtggtgtgtgaccttgggaacccgatggtgactggaacgaatttttctctgggc
ctccgatttgctgttcctcgtcttgagaaaacaaacatgagtattaacttcgatctccaa
atcagaagctccaacaaggacaatcctgacagcaatttcgtgagcgtgcaaatcaacgtc
actgccgtggctcaggtggaaatcagaggagtgtcccaccctccccaaattgttctgccc
atccacaactgggagccagcagaggagccccacaaagaggaggaagtcggtcccctggtt
gaacatatttatgagctgcacaatattggacccagcaccatcagtgacagcattctcgaa
gtgggctggccattctctgcacgggaggagttcctcctctatgtctttcatcttcaaact
ctgggacctctacaatgtcaaacaaatcctgagatcaacccgcaggatataaagcctgct
gcctccccagaggatacccctgagctcagcgccttcttaagaaatgctacaattccccat
cttgtcaggaagagggatgtgccagtggtccagccccacagacagagcccggcaaaaata
ctgaactgtaccaacattgactgcttgcaaatctcgtgtgcagtgggtcgcctgggagga
ggagaaagtgcagttctgaaggtcagatcgagattgtgggcgcacacattcctccagaga
aagaacgacccttatgctcttgcatccctggtgtcctttgaagtcaagaagataccttat
aaagagcagccagcaaaactgccagccgggagcacagcgattaagacatcggttatttgg
gccactccaaatgtctccttctcaattccactgtgggtcataatactagcgatccttctt
ggcttgctggttctggccatcttaactttagctttatggaagtgtggattctttgataga
gcaagacctcctcaggatgaaatgacagacagggaacaactgaccagtgacaagaccccg
gaggcttga

All links

Pathway (8)   
   KEGG PATHWAY (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (3)   
   UniGene (1)   
   ENSEMBL-RNO (1)   
   OC (1)   
   RGD (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (4)   
   Pfam (4)   
All databases (29)   

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