KEGG   Rattus norvegicus (rat): 396527Help
Entry
396527            CDS       T01003                                 

Gene name
Ugt1a2, UDPGT_1-2, Udpgt, Ugt1
Definition
(RefSeq) UDP glucuronosyltransferase 1 family, polypeptide A2
  KO
K00699  glucuronosyltransferase [EC:2.4.1.17]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00040  Pentose and glucuronate interconversions
rno00053  Ascorbate and aldarate metabolism
rno00140  Steroid hormone biosynthesis
rno00830  Retinol metabolism
rno00860  Porphyrin and chlorophyll metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno05204  Chemical carcinogenesis
Module
rno_M00014  Glucuronate pathway (uronate pathway)
rno_M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
KEGG Orthology (KO) [BR:rno00001]
 Metabolism
  Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    396527 (Ugt1a2)
   00053 Ascorbate and aldarate metabolism
    396527 (Ugt1a2)
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    396527 (Ugt1a2)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    396527 (Ugt1a2)
   00860 Porphyrin and chlorophyll metabolism
    396527 (Ugt1a2)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    396527 (Ugt1a2)
   00982 Drug metabolism - cytochrome P450
    396527 (Ugt1a2)
   00983 Drug metabolism - other enzymes
    396527 (Ugt1a2)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    396527 (Ugt1a2)
Enzymes [BR:rno01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     396527 (Ugt1a2)
Glycosyltransferases [BR:rno01003]
 Others
  Hydrophobic molecule
   396527 (Ugt1a2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: UDPGT Glyco_tran_28_C Glyco_transf_4 Pox_A14
Motif
Other DBs
NCBI-GeneID: 396527
NCBI-ProteinID: NP_958826
RGD: 1549741
Ensembl: ENSRNOG00000018740
UniProt: Q6T5F2
Position
9q35
AA seq 533 aa AA seqDB search
MDTGLCAPLRGLSGLLLLLCALPWAEGGKVLVFPMEGSHWLSMRDVVRELHARGHQAVVL
APEVTVHMKGEDFFTLQTYAFPYTKEEYQREILGNAKKGFEPQHFVKTFFETMASIKKFF
DLYANSCAALLHNKTLIQQLNSSSFDVVLTDPVFPCGALLAKYLQIPAVFFLRSVPCGID
YEATQCPKPSSYIPNLLTMLSDHMTFLQRVKNMLYPLTLKYICHLSITPYESLASELLQR
EMSLVEVLSHASVWLFRGDFVFDYPRPIMPNMVFIGGINCVIKKPLSQEFEAYVNASGEH
GIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDL
LGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTA
DDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHD
LTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH
NT seq 1602 nt NT seq  +upstreamnt  +downstreamnt
atggacacaggattgtgtgcaccccttcgaggactctcaggactgctgctcctgctgtgt
gccctgccctgggctgaaggtggaaaggtgctggtgtttcccatggagggcagccactgg
ctgagcatgagggatgtcgtgagggagctccacgcccgaggtcaccaggctgtggtcctg
gctccagaggtgactgtgcacatgaaaggagaggacttcttcaccctccaaacctatgcc
tttccatataccaaggaagaatatcagcgggaaatactgggcaacgctaagaagggcttc
gaaccacaacattttgtgaagactttctttgaaactatggcatctataaaaaagtttttc
gatctctacgcaaattcttgtgcagctctattgcacaataagaccctgatccagcaactg
aattccagttccttcgatgtggtcttaacagaccctgttttcccctgtggagcattactg
gccaagtatctacagattcctgctgtgttttttctgcgctctgttccctgtggcatagac
tatgaggctacacaatgtccgaaaccttcctcttatattccgaacctactcacaatgctt
tctgaccacatgaccttcctgcaaagggtcaagaacatgctgtaccctctgaccttgaag
tacatttgccatttatcaatcactccctatgaaagcctggcctctgagcttttgcagaga
gaaatgtctttagtggaggttctcagtcatgcatctgtgtggctgttccgaggggacttt
gtgtttgactacccgaggcccatcatgcctaatatggtcttcattggaggcataaactgt
gtcatcaagaagcccctctctcaggaatttgaagcctatgtcaacgcctccggagaacat
ggcatcgtggttttctctttgggatccatggtctcagagattccagagaagaaagcgatg
gaaattgctgaggctttgggcagaattcctcagacggtcctgtggcgctacaccggaact
agaccatcgaaccttgcaaagaacactattcttgtcaaatggctaccccaaaacgatctg
cttggtcatccaaaggctcgggcgttcatcacacactccggttcccatggtatttatgaa
ggaatatgcaatggggttccaatggtgatgatgcccttgtttggtgatcagatggacaac
gccaagcgcatggaaactcggggagctggggtgaccctgaatgtcctggaaatgactgcc
gatgatttggaaaacgcccttaaaactgtcatcaataacaagagttacaaggagaacatc
atgcgcctctccagccttcacaaggaccgtcctatcgagcctctggacctggctgtgttc
tgggtggagtacgtgatgaggcacaagggggcgccacacctgcgccccgccgcccacgac
ctcacctggtaccagtaccactccttggacgtgattggctttctcctggccatcgtgttg
acggtggtcttcattgtctataaaagttgtgcctatggctgccggaaatgctttggggga
aagggtcgagtgaagaaatcacacaaatccaagacccactga

DBGET integrated database retrieval system