KEGG   Rattus norvegicus (rat): 445442Help
Entry
445442            CDS       T01003                                 

Gene name
Thbs1, TSP-1, Tsp1
Definition
thrombospondin 1
Orthology
K16857  
thrombospondin 1
Organism
rno  Rattus norvegicus (rat)
Pathway
Rap1 signaling pathway
p53 signaling pathway
Phagosome
PI3K-Akt signaling pathway
TGF-beta signaling pathway
Focal adhesion
ECM-receptor interaction
Malaria
Proteoglycans in cancer
MicroRNAs in cancer
Bladder cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    445442 (Thbs1)
   04350 TGF-beta signaling pathway
    445442 (Thbs1)
   04151 PI3K-Akt signaling pathway
    445442 (Thbs1)
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    445442 (Thbs1)
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    445442 (Thbs1)
  Cell growth and death
   04115 p53 signaling pathway
    445442 (Thbs1)
  Cell communication
   04510 Focal adhesion
    445442 (Thbs1)
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    445442 (Thbs1)
   05205 Proteoglycans in cancer
    445442 (Thbs1)
   05219 Bladder cancer
    445442 (Thbs1)
  Infectious diseases
   05144 Malaria
    445442 (Thbs1)
Heparan sulfate/heparin binding proteins [BR:rno00536]
 Extracellular matrix molecules (General comment) Storage depot, cell adhesion and motility, ECM/barrier formation
  445442 (Thbs1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
UniProt: 
Position
3
AA seq 1170 aa AA seqDB search
MELLRGLGVLFLLHVCGSNRIPESGGDNGVFDIFELIGGARKVPGRRLVKGQDLSSPAFR
IENANLIPPVPDDKFQDLLDAVWADKGFIFLASLRQMKKTRGTLLAVERKDNSGQIFSVV
SNGKAGTLDLSLSLPGKQQVVSVEEALLATGQWKSITLFVQEDRAQLYIDCDKMESAELD
VPIQSIFTRDLANVARLRVAKGDVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTNVLL
TLDNNVVNGSSPAIRTNYIGHKTKDLQAICGLSCDELSSMVLELRGLRTIVTTLQDSIRK
VTEENRELASELRRPPLCFHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSN
ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSATCGNGIQQRGRSCDSLNNRCEGSSVQT
RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARE
TKACKKDACPINGGWSPWSLWDICSVTCGGGVQRRSRLCNNPTPQFGGKDCVGDVTENQV
CNKQDCPIDGCLSNPCFAGAKCTSYPDGSWKCGACPPGYSGNGIQCKDVDECKEVPDACF
NHNGEHRCKNTDPGYNCLPCPPRFTGSQPFGRGVEHAMANKQVCKPRNPCTDGTHDCNKN
AKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPN
LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN
HNPDQADTDNNGEGDACAVDIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEH
NPDQLDSDSDRIGDTCDNNQAIDEDGHQNNLENCPYVPNANQADHDKDGKGDACDHDDDN
DGIPDDRDNCRLVPNPDQKDSDGDGRGDACKDDFDHDNVPDIDDICPENVDISETDFRRF
QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD
DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL
WHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGLIRVVMYEGKKIMADSGPIYD
KTYAGGRLGLFVFSQEMVFFSDMKYECRDS
NT seq 3513 nt NT seq  +upstreamnt  +downstreamnt
atggagctcctcaggggactaggcgtcctgttcctgttgcatgtgtgtggaagcaaccgc
attccagagtctgggggagacaatggtgtgttcgacatttttgaactcattggaggtgcc
cgcaaggttccgggtcgccgactggtgaagggccaagatctatccagccccgccttccgg
atcgagaatgccaacctgatcccccctgtgccagatgacaagttccaagacctactggac
gctgtgtgggccgacaaaggcttcatcttcctggcttccttgaggcagatgaagaagact
cggggcacactcctggccgtggaacggaaagacaattctggccagatcttcagtgtggtc
tccaatggcaaagccggcaccctcgatctgagtctgagcctgcccgggaagcagcaagtg
gtgtcagtggaggaagctctcctggccactggccagtggaagagcatcacgctgtttgtc
caagaagacagggcccagctctacattgactgtgacaagatggagagcgcagagctggat
gttcccatccagagcatcttcacaagggatttggccaatgtcgccaggctccgagtcgca
aagggagatgtcaatgacaattttcagggggtgctgcagaatgtgaggtttgtctttgga
accaccccagaagacattctcaggaacaaaggctgctccagttcaaccaacgtccttctc
acccttgacaacaacgtggtgaacggttccagccctgccatccgcaccaactacatcggc
cacaaaacaaaggacctccaagccatctgtggcctctcctgtgacgaactatccagcatg
gtcctggaactgaggggcctgcgtaccatcgtgaccacgctacaggacagcattcgcaaa
gtgacggaagagaacagagagctggctagcgagctgaggcggcctcccctctgcttccac
aatggagtccaatacaggaacaacgaggagtggactgtagatagttgcacagagtgtcac
tgccagaactcagttaccatctgcaaaaaggtgtcctgtcccatcatgccctgctccaat
gccacagttcctgatggtgaatgctgcccacggtgctggcccagtgactctgctgacgat
ggctggtctccctggtctgagtggacctcttgctctgccacctgtggcaatgggattcag
caacgtggtcgctcctgtgacagcctcaacaacagatgtgagggctcttcagtacagacg
aggacctgccacattcaggagtgcgacaaaagatttaaacaggatggtggttggagtcac
tggtccccgtggtcgtcctgttctgtgacctgtggtgacggtgtgatcacgaggatccga
ctctgcaactcccccagcccccagatgaacgggaagccctgtgaaggtgaagctcgggag
accaaagcctgcaagaaggacgcctgcccaatcaatggaggctggagtccctggtcacta
tgggacatctgctctgtcacctgtggaggaggagtacagagacgtagccgactctgcaac
aaccccacaccccagtttggaggcaaagactgtgttggtgatgtgacggaaaatcaagtt
tgcaacaagcaggactgtccgattgatggatgcctgtccaatccctgctttgctggtgcc
aagtgtacgagctatcctgatggtagctggaaatgtggtgcgtgtcctcctggctacagt
ggaaatggtatccagtgcaaagacgtcgacgagtgcaaagaagtgcctgatgcttgcttc
aatcacaacggggaacatcggtgcaagaacacagatcctggctacaactgcctgccctgc
ccaccacgattcaccggctcacagcccttcggcagaggtgtcgaacacgctatggccaac
aaacaggtgtgcaaaccccgaaacccctgcaccgacgggacacacgactgcaacaagaac
gccaagtgcaactacctgggtcactacagcgaccccatgtaccgctgcgagtgcaagcct
ggctatgcaggcaatggcatcatttgcggagaggacacagaccttgacggctggcctaat
gaaaacctggtgtgtgtggccaacgcaacctaccactgcaaaaaggacaactgccccaat
cttcccaattcggggcaggaagactatgacaaggatgggattggcgatgcctgtgatgac
gatgatgacaacgacaagattcctgatgacagggacaactgtccattccattacaaccct
gcccagtatgactatgacagagatgatgtgggagaccgctgtgacaattgcccctacaac
cacaaccctgaccaggcagacacagacaacaatggggagggagatgcctgcgctgtggac
atcgatggggatggaatcctcaatgaacgagacaactgccagtatgtttacaacgtggat
cagagggacacggacatggatggggttggagaccagtgtgacaactgccccctggaacac
aatccagaccagctggactctgactcggaccgcataggggacacctgtgacaacaatcag
gccatcgatgaggatggccatcagaacaaccttgaaaactgtccctatgtgcccaatgcc
aaccaggccgaccacgataaagatggtaaaggagacgcctgtgaccatgacgatgacaac
gacggcatccctgatgacagagacaactgcaggctggtgcccaatcctgaccagaaggac
tctgatggtgatggccgaggcgatgcctgcaaagacgactttgaccatgacaatgtgcca
gacattgatgacatctgtcctgagaatgttgacatcagtgaaaccgatttccgccgattc
cagatgattcctctagatcccaaaggaacctcccaaaatgaccctaactgggttgtccgc
catcagggcaaagaacttgtccagactgtaaactgtgaccctggacttgctgtaggttat
gatgagtttaatgccgtggacttcagtggtaccttcttcatcaacactgagagggatgac
gactatgctggctttgttttcgggtaccagtccagcagccgcttctacgttgtgatgtgg
aaacaagtcacccagtcctactgggacaccaaccccacaagggctcagggatactcaggc
ctgtctgtaaaggttgtaaactccaccactggccccggcgagcacctgcggaatgcactg
tggcacacaggaaacacccctggccaggtgcgcaccctgtggcatgaccctcgtcacatt
ggctggaaagatttcactgcatacagatggcgtctcagccacaggccaaagaccggtttg
atcagagtggtgatgtatgaaggaaagaaaatcatggctgactcaggacccatctatgac
aaaacctacgctggcggtagactaggcctgttcgtcttctctcaagaaatggtgttcttc
tcggacatgaaatacgagtgccgagactcctaa

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