KEGG   Rattus norvegicus (rat): 497931Help
Entry
497931            CDS       R.norvegicus                           
Gene name Pik3r5, RGD1563261_predicted
Definition phosphoinositide-3-kinase, regulatory subunit 5
Orthology K02649  phosphoinositide-3-kinase, regulatory subunit
Pathway rno04012  ErbB signaling pathway
rno04062  Chemokine signaling pathway
rno04070  Phosphatidylinositol signaling system
rno04150  mTOR signaling pathway
rno04210  Apoptosis
rno04370  VEGF signaling pathway
rno04510  Focal adhesion
rno04620  Toll-like receptor signaling pathway
rno04630  Jak-STAT signaling pathway
rno04650  Natural killer cell mediated cytotoxicity
rno04660  T cell receptor signaling pathway
rno04662  B cell receptor signaling pathway
rno04664  Fc epsilon RI signaling pathway
rno04666  Fc gamma R-mediated phagocytosis
rno04670  Leukocyte transendothelial migration
rno04722  Neurotrophin signaling pathway
rno04810  Regulation of actin cytoskeleton
rno04910  Insulin signaling pathway
rno04914  Progesterone-mediated oocyte maturation
rno04930  Type II diabetes mellitus
rno04960  Aldosterone-regulated sodium reabsorption
rno05200  Pathways in cancer
rno05210  Colorectal cancer
rno05211  Renal cell carcinoma
rno05212  Pancreatic cancer
rno05213  Endometrial cancer
rno05214  Glioma
rno05215  Prostate cancer
rno05218  Melanoma
rno05220  Chronic myeloid leukemia
rno05221  Acute myeloid leukemia
rno05222  Small cell lung cancer
rno05223  Non-small cell lung cancer
Class Environmental Information Processing; Signal Transduction; ErbB
signaling pathway [PATH:rno04012]
Environmental Information Processing; Signal Transduction; VEGF
signaling pathway [PATH:rno04370]
Environmental Information Processing; Signal Transduction; Jak-STAT
signaling pathway [PATH:rno04630]
Environmental Information Processing; Signal Transduction;
Phosphatidylinositol signaling system [PATH:rno04070]
Environmental Information Processing; Signal Transduction; mTOR
signaling pathway [PATH:rno04150]
Cellular Processes; Cell Motility; Regulation of actin cytoskeleton
[PATH:rno04810]
Cellular Processes; Cell Growth and Death; Apoptosis [PATH:rno04210]
Cellular Processes; Cell Communication; Focal adhesion
[PATH:rno04510]
Organismal Systems; Immune System; Toll-like receptor signaling
pathway [PATH:rno04620]
Organismal Systems; Immune System; Natural killer cell mediated
cytotoxicity [PATH:rno04650]
Organismal Systems; Immune System; T cell receptor signaling pathway
[PATH:rno04660]
Organismal Systems; Immune System; B cell receptor signaling pathway
[PATH:rno04662]
Organismal Systems; Immune System; Fc epsilon RI signaling pathway
[PATH:rno04664]
Organismal Systems; Immune System; Fc gamma R-mediated phagocytosis
[PATH:rno04666]
Organismal Systems; Immune System; Leukocyte transendothelial
migration [PATH:rno04670]
Organismal Systems; Immune System; Chemokine signaling pathway
[PATH:rno04062]
Organismal Systems; Endocrine System; Insulin signaling pathway
[PATH:rno04910]
Organismal Systems; Endocrine System; Progesterone-mediated oocyte
maturation [PATH:rno04914]
Organismal Systems; Excretory System; Aldosterone-regulated sodium
reabsorption [PATH:rno04960]
Organismal Systems; Nervous System; Neurotrophin signaling pathway
[PATH:rno04722]
Human Diseases; Cancers; Pathways in cancer [PATH:rno05200]
Human Diseases; Cancers; Colorectal cancer [PATH:rno05210]
Human Diseases; Cancers; Pancreatic cancer [PATH:rno05212]
Human Diseases; Cancers; Glioma [PATH:rno05214]
Human Diseases; Cancers; Acute myeloid leukemia [PATH:rno05221]
Human Diseases; Cancers; Chronic myeloid leukemia [PATH:rno05220]
Human Diseases; Cancers; Melanoma [PATH:rno05218]
Human Diseases; Cancers; Renal cell carcinoma [PATH:rno05211]
Human Diseases; Cancers; Prostate cancer [PATH:rno05215]
Human Diseases; Cancers; Endometrial cancer [PATH:rno05213]
Human Diseases; Cancers; Small cell lung cancer [PATH:rno05222]
Human Diseases; Cancers; Non-small cell lung cancer [PATH:rno05223]
Human Diseases; Metabolic Diseases; Type II diabetes mellitus
[PATH:rno04930]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: PI3K_1B_p101
Motif
Other DBs NCBI-GI: 109491043
NCBI-GeneID: 497931
RGD: 1563261
RATMAP: ENSRNOG00000023428
Ensembl: ENSRNOG00000023428
Position 10q24
AA seq 872 aa AA seqDB search
MQPAATTCTEDRIQHALERCLHGLSLGRRSAPWSAGLCLNCWSLQELVSRDPGHFLILLE
QILQKTQEVQEKGTYDLLAPLALLFYSTVLCTPHFPPDSDLLLKAASTYHCFLTWPVPYC
SICREMLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVAD
KLSTPGQSPHGAYTTLLLHAFQATFGTHCDLPKLHRKLQSKTLEELEDIFTETTEAQELA
SGIGDVAEARQWLRTKLQAVGEKAGFPGILDTASPGKLHTIPIPVARCYTYSWNQDSFDI
LQEVLLKEQELLQPGILGDDEEEEEEDLEIDRHIAERDSLLSTGSLVSHDSELLLTSSQA
SGPVLSRQVLTTFVSGLSDGMDSGYVEDSEESSSEWPKKPGSQQRQGHRRPRQKFNRFYK
LLKSTSQLVLRRDSRSLECSPDPTLPLRRAGSLSSPLDFPTQLPSRAQRSRSLPQPKLST
QLPSWLLAPPSHHQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSKLRRLENSHP
ILTRFFKLQFFYVPVKRSHGASSSACLSSLNQASPLLPDSLKHPSPADLGKAPWEDSTND
ISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAESRPLEGSATQLPILADMLLYYCRFA
ARPVLLQVYQTELTFVTGEKTTEIFIQSLELGHSATTRAIKASGPGSKRLGIGDDREAVP
LTLQIIYSKGAISGRSRWSNLEKVCTSVNLSKACQKPEELDSSMEALTLTLTEVVKRQNP
KSKKGFNQISTSYIKVDKVQIISSSSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSSL
PPEGSLSQPAEAGSDLCSLLCLPIMTFSGALP
NT seq 2619 nt NT seq  +upstreamnt  +downstreamnt
atgcagccagcagccacaacgtgcacagaggaccgcatccagcacgctctggagagatgc
ttgcatggactgagcctcggacgccgttctgctccctggtcagccgggctgtgtctgaac
tgctggagcctacaggagctggtcagcagggacccgggccacttcctcatcctcctggaa
cagatcctgcagaagacccaagaggtccaagagaagggcacctatgacctcctcgcccct
ctggctctgctcttctattccactgtcctctgcactccacacttcccaccagactcagac
ctcctgctgaaggcagccagcacctaccactgcttcctgacctggccggttccctactgc
agcatctgccgagagatgctcaccttcatcgatgctgagctcaaggccccaggaatctcc
taccagcggctggtgagggctgaacagggcctgcccatcaggagccaccgaagttccact
gtcactgtgctgttgctgaacccggtagaggtacaggctgagttcctcgctgtggcagac
aagctgagcacaccgggacagtcaccccatggcgcctacaccaccctgctcctgcatgcc
ttccaggccacctttgggacccactgtgaccttcctaaactgcaccgcaaacttcagtcc
aagacgctagaagagctcgaggacatcttcactgagactacagaagcccaggagctggca
tctggcattggggatgtagcagaggcccgtcagtggctccggaccaagctgcaggcagtg
ggagaaaaagccggcttccccgggatcttagacactgcaagccctgggaaactccacacg
attcccatccctgtcgccagatgctacacttacagctggaatcaggacagctttgacatc
ctacaggaagtccttctcaaggagcaggagttgctgcagccagggatcctgggagatgat
gaagaggaggaagaggaggacttggagattgacaggcatattgctgagagggactccctg
ctctccacaggctctctggtgtctcacgactccgaactgttgcttacctcctctcaggcc
tcaggaccagtgctgtcccgccaggtgctgaccacctttgtctcaggcctctcggatggc
atggacagtggctacgttgaggacagtgaggaaagctcctcagagtggcccaagaagccg
ggcagccagcagcgccagggtcaccgcaggcctaggcagaagttcaacaggttctataaa
cttttaaagagcaccagccagttggtcctgaggagggactctcggagtctggaatgcagc
ccagacccaaccctgcctctgcggcgggcagggagcctcagcagccccttggactttccg
acccagctcccttccagggctcagcgctcacggtccctaccccagcccaagctcagcacc
caactacccagctggcttctggcaccaccctcacaccaccagcgccgccgtcccttcctc
agcggggatgaggaccccaaggcttccacactacgggttgtggtctttggctctgaccgg
atctcagggaaggtggcccgggcctatagcaagctcaggcggctggagaacagtcacccg
atcctcacccggttcttcaagcttcagttcttctacgtacctgtgaagagaagccacgga
gccagctctagtgcctgcctatcctctctgaaccaggcatctccactccttccagactcc
ttgaagcaccccagccctgcagaccttggcaaggccccatgggaggacagtaccaatgac
atctctcactacctcggtatgcttgacccttggtatgaacgcaatgtgttgggcctcatg
catctgcctcctgaagtcctgtgtcagcagtccctcaaggcagaatctcggcccctggag
ggctcggccacccagctgcccatcctggccgatatgttactctactactgccgctttgca
gcccgcccagtgttgctgcaggtttatcagacagagctgaccttcgtcaccggggagaag
accacggagatctttatccagtctctggagctgggtcactctgcgaccactcgtgctatc
aaggcttcaggtccgggaagcaaaaggctgggcattggcgatgaccgggaggccgtccct
ctaacactacagattatttacagcaagggagccatcagtgggcgaagccgctggagcaac
ctagagaaggtctgcacctctgttaacctcagcaaggcctgccagaagccggaggaacta
gattccagcatggaggcgctgacgctaaccctgacagaagtggtgaagaggcagaaccct
aaatccaaaaagggctttaaccagatcagtacatcctacatcaaagtggacaaggtgcag
atcatcagctccagcagctgcccctttgctgtgtgtctagaccaggatgagaggaagatc
ctgcagagtgtggtcaggtgtgaagtgtcaccctgctacaagccagagaagagcagcctg
ccacctgaggggtccctcagccaaccagcagaggctgggtctgacctgtgctcccttctc
tgccttcccatcatgactttcagtggtgctctgccctag
DBGET integrated database retrieval system