KEGG   Rattus norvegicus (rat): 50678Help
Entry
50678             CDS       T01003                                 

Gene name
Pde3a, RNPDE3A
Definition
(RefSeq) phosphodiesterase 3A (EC:3.1.4.17)
  KO
K19021  
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
Organism
rno  Rattus norvegicus (rat)
Pathway
Purine metabolism
cGMP-PKG signaling pathway
cAMP signaling pathway
Renin secretion
Morphine addiction
Brite
KEGG Orthology (KO) [BR:rno00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    50678 (Pde3a)
 Environmental Information Processing
  Signal transduction
   04024 cAMP signaling pathway
    50678 (Pde3a)
   04022 cGMP - PKG signaling pathway
    50678 (Pde3a)
 Organismal Systems
  Endocrine system
   04924 Renin secretion
    50678 (Pde3a)
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    50678 (Pde3a)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     50678 (Pde3a)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
4q44
AA seq 1141 aa AA seqDB search
MAVRGEAAQDWAKPGLRGPSPAPVARGDHRCRGGSPSSPRGSGCCWRALALQPLRRSPQL
SSALCAGSLSVLLALLVRLVGGEVGGELESSQEAAAEEEEEEGARGGVFPGPRGGAPGGG
AQLSPWLQPAALLFSLLCAFFWMGLCLLRAGVRLPLAVALLAACCAGEALVQLSLGVGDG
RLLSLPAAGVLLSCLGGATWLVLRLRLGVLMVALTSALRTVALVSLERFKVAWRPYLAYL
AAVLGLLLARYAEQLLPQCSGPAPPRERFGSQSSARTKEEIPGWKRRRRSSSVVAGEMSG
CGGKSHRRTSLPCIPREQLMGHSEWDHKRGSRGSQSGTSVTVDIAVMGEAHGLITDLLAD
PSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPTVTFSENYTCSDSEEGLEKDKLAIPK
RLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKPHEAPSPSAVNPDSWN
APVLMTLTKSRSFTSSYAVSAANHVKAKKQNRPGGLDKISPVPSPSSSPPQGSPTSSPVS
GIASVQFPESPEVTTKRGPGSHRALTYTQSAPDLSPQIPPSPVICSSCGRPYSQGNPADG
PSERSGPAMQKPNRTDDTSQVTSDYETNNNSDSSDILQNDEEAECQREPLRKASACGTYT
PQTMIFLDKPILAPEPLVMDNLDSIMDQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFE
DMGLFEAFKIPVREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLPSVIG
DHGSASDSDSDSGFTHGHMGYVFSKAYHVPDDKYGCLSGNIPALELMALYVAAAMHDYDH
PGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFL
VIEAILATDLKKHFDFVAKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKDL
HLRWTEGIASEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCHSYDSAG
LMPGKWVDDSDDSGDTDDPEEEEEEAETPHEEETCENSEAPRKKSFKRRRIYCQITQHLL
QNHMMWKKVIEEEQCLSGTENQAPDQAPLQHSSEQIQAIKEEEEEKGKPRAEETLAPQPD
L
NT seq 3426 nt NT seq  +upstreamnt  +downstreamnt
atggcagtgcggggcgaggccgcccaagactgggccaagcccggtctccgagggccgagt
cctgccccggtggccagaggggaccaccgctgtcgtggcgggtccccttcatcccctcgg
ggctcgggctgttgttggcgagccctggcgttgcagcctctccggcgctcgccgcaactc
tcctccgcgttgtgcgcgggctccctgtccgtgctgctggcgctgctggtgaggctggtc
ggcggggaggtcggaggcgagctggagtcgagtcaggaggcggcggccgaggaggaggag
gaggaaggagcccgagggggcgtcttcccgggccctcggggaggtgctcccgggggcggc
gcgcagctcagcccttggctgcagccggccgcgctgctcttcagtctcctgtgcgccttc
ttctggatgggcttgtgcctgctgcgcgccggggtgcgcctgcctctggccgtcgcgctg
ttggccgcctgctgcgccggggaagcgctggtgcagctctccttgggcgtgggggacggt
cgcctgctgtcgctacccgccgcgggggtcctgctcagctgcctaggtggcgcgacatgg
ctggtgctgaggctgaggctgggcgtcctcatggtcgctttgactagcgccctcaggacg
gtggccctggtttctctggagaggttcaaggtcgcctggagaccttacctggcatacttg
gcggccgtgcttgggctgctgctggccaggtacgccgagcagctcctgccgcagtgctcc
gggccggctccgcccagggagcggtttgggtcccagtcgagcgcgaggaccaaggaagag
attccggggtggaagaggaggaggcggtccagctcggtggtggccggcgagatgtccggc
tgcggtggcaagtctcaccggaggacctccctgccctgcatacccagggagcagctcatg
ggccattcagaatgggaccacaagagagggtcacgaggatcccagtcaggaaccagcgtc
accgtggatattgccgtgatgggcgaggcgcatggcctcattaccgacctcctggccgac
ccttctttgcctccgaatgtgtgcacgtccttgagggccgtgagcaacctgctcagtacc
cagctcaccttccaggcaatccacaagcccagagtgaaccccactgtgaccttcagtgag
aactatacctgctccgactctgaggaaggcttggagaaagacaagctggccattcccaag
cgcctgagaagaagtttgcctccaggcttgctgaggagagtttcatcaacttggacaact
accacctctgccacaggactgcctaccttggagcctgcgccagtgcggagggaccgcagc
gccagcataaagccacatgaagccccttcacccagtgctgtcaaccctgactcttggaat
gccccagtgttgatgactctaaccaaaagcaggtccttcacttcgtcctatgctgtctct
gcagctaaccacgtcaaagctaaaaagcaaaacaggccaggtggccttgataagatttcg
cccgttccctcgccctcctcctcacctcctcaaggatcacccaccagcagtcctgtcagt
ggcattgcttccgtacagttcccggaatcccctgaagtcaccaccaaacgaggccctgga
tctcacagggccttaacttacacccagagtgcccctgacctgtccccccagatcccgccc
tcacctgtcatatgtagcagctgtggcagaccttactcacaagggaatcctgctgatgga
ccttcagagagaagtggcccagccatgcagaaaccaaacagaacagatgatacttctcaa
gttacctctgattatgagaccaacaacaacagtgacagcagcgacatcctgcagaatgat
gaggaagccgagtgccagagagagccactgaggaaagcatcggcttgtggcacctatact
ccccagaccatgatcttcctggacaaaccaattcttgctccagaacccctggtcatggat
aacctggattcaattatggatcagttgaacacctggaattttccaatttttgatttagtg
gaaaacataggaagaaaatgtggccgtattctgagccaggtgtcatacagactctttgaa
gacatggggctctttgaagcctttaaaatcccggttagggagtttatgaattactttcat
gctttggagatcggctacagggacattccttatcataacagaatccacgccactgatgtt
ttgcacgccgtgtggtatctcacaacacagccgattcctggcctcccgagtgtgattggt
gatcacggctcggcaagtgactctgattctgacagtgggtttacacacggacacatggga
tatgtgttttccaaagcgtatcatgtgccagatgacaaatatggatgcctgtctggaaat
attccagccctggagttgatggccctgtatgttgctgcagccatgcatgactacgatcac
ccaggaaggacaaatgctttcctggttgccactagcgcccctcaggccgtgctgtacaat
gaccgttccgttctggagaaccatcacgcagctgcagcctggaatctcttcatgtcccgg
ccggagtataacttcttagttaacctggaccatgtggaatttaagcacttccgattccta
gtcattgaagcaattctggctactgacctgaagaaacactttgactttgtagccaagttt
aatgccaaggtgaatgatgatgttgggatagattggaccaatgaaaacgaccgtctcctg
gtgtgtcagatgtgtataaagttggctgacatcaacgggcctgctaaatgtaaggacctc
cacctgcggtggacggagggcatcgccagcgagttttatgagcagggcgatgaagaagcc
agccttggtttgcccataagcccatttatggaccgctctgccccgcagctggccaatctt
caggagtcctttatctcacacatcgtgggtcctctttgccactcctacgactctgcgggt
ctcatgccgggaaaatgggtagatgacagtgatgattcaggagacactgatgacccggaa
gaagaggaggaagaggctgaaacaccacacgaggaagaaacctgtgaaaacagtgaagct
cccagaaagaaaagtttcaaaagaaggagaatctactgtcaaataactcagcaccttctg
cagaaccacatgatgtggaagaaagtgattgaagaggagcagtgtttatcaggcacagag
aaccaggccccagaccaggcaccgctgcagcattcctcagaacaaatccaggctatcaag
gaggaggaggaagagaaggggaagccaagagcagaggaaaccctcgctccacaaccagac
ctgtga

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