KEGG   Rattus norvegicus (rat): 58918Help
Entry
58918             CDS       T01003                                 

Gene name
Casp9, Apaf3, Casp-9-CTD, Casp9_v1, Ice-Lap6, Mch6
Definition
(RefSeq) caspase 9 (EC:3.4.22.62)
  KO
K04399  
caspase 9 [EC:3.4.22.62]
Organism
rno  Rattus norvegicus (rat)
Pathway
p53 signaling pathway
PI3K-Akt signaling pathway
Apoptosis
Apoptosis - multiple species
VEGF signaling pathway
Thyroid hormone signaling pathway
Alzheimer's disease
Parkinson's disease
Amyotrophic lateral sclerosis (ALS)
Huntington's disease
Legionellosis
Toxoplasmosis
Tuberculosis
Hepatitis B
Influenza A
Pathways in cancer
Colorectal cancer
Pancreatic cancer
Endometrial cancer
Prostate cancer
Small cell lung cancer
Non-small cell lung cancer
Viral myocarditis
Module
Apoptotic machinery
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04370 VEGF signaling pathway
    58918 (Casp9)
   04151 PI3K-Akt signaling pathway
    58918 (Casp9)
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    58918 (Casp9)
   04215 Apoptosis - multiple species
    58918 (Casp9)
   04115 p53 signaling pathway
    58918 (Casp9)
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    58918 (Casp9)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    58918 (Casp9)
   05210 Colorectal cancer
    58918 (Casp9)
   05212 Pancreatic cancer
    58918 (Casp9)
   05215 Prostate cancer
    58918 (Casp9)
   05213 Endometrial cancer
    58918 (Casp9)
   05222 Small cell lung cancer
    58918 (Casp9)
   05223 Non-small cell lung cancer
    58918 (Casp9)
  Neurodegenerative diseases
   05010 Alzheimer's disease
    58918 (Casp9)
   05012 Parkinson's disease
    58918 (Casp9)
   05014 Amyotrophic lateral sclerosis (ALS)
    58918 (Casp9)
   05016 Huntington's disease
    58918 (Casp9)
  Cardiovascular diseases
   05416 Viral myocarditis
    58918 (Casp9)
  Infectious diseases
   05134 Legionellosis
    58918 (Casp9)
   05152 Tuberculosis
    58918 (Casp9)
   05164 Influenza A
    58918 (Casp9)
   05161 Hepatitis B
    58918 (Casp9)
   05145 Toxoplasmosis
    58918 (Casp9)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.62  caspase-9
     58918 (Casp9)
Protein phosphatases and associated proteins [BR:rno01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     58918 (Casp9)
Peptidases [BR:rno01002]
 Cysteine Peptidases
  Family C14: caspase family
   58918 (Casp9)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
5q36
AA seq 454 aa AA seqDB search
MEEADRQLLRRCRVRLVRELQVAELWDALLSRELFTRDMIEDIQRAGSGSRRDQARQLVI
DLETRGRQALPRFISCLEDTGQGSLASFLQSSGQAAKQDPEAVTPLDHLVPVVLGPMGLK
SKEQKVVKLDPSQPALGNLTPVVLGPEELWPTRLRPEVLTPETPRPVDIGSGRAHDVCTP
GKIERHADMAYTLDSDPCGHCLIINNVNFCPSSGLSTRIGSHVDCEKLQHRFCWLRFMVE
VKNDLTAKKMVTALMEMAHRDHRALDCFVVVILSHGCQASHLQFPGAVYGTDGCSVSIER
IVNIFNGTGCPSLGGKPKLFFIQACGGEQKDHGFEVAFTSSQDKAFDSDSEPDAVPYQEG
PRTLDQLDAVSSLPTPSDILVSYSTFPGFVSWRDKKSGSWYIETLDGVLEQWARSEDLQS
LLLRVANAVSEKGVYKQIPGCFNFLRKKLFFKTS
NT seq 1365 nt NT seq  +upstreamnt  +downstreamnt
atggaggaggctgaccggcaactcctgcggcgatgcagggtacgccttgtgcgcgaactg
caagtcgcggagctgtgggacgctctgctgagtcgtgagctcttcacgcgcgacatgatc
gaggatattcagcgggcaggctctgggtctcggcgggatcaggccaggcagctggtcata
gatcttgagactcgagggaggcaggcccttcctcgcttcatctcctgcttagaggacaca
ggccaaggctctctggcttcattcttgcaaagcagtgggcaagcagccaagcaggatcca
gaagctgttacacccctagaccacctggtgcctgtggtcctgggaccaatgggactcaaa
tcaaaggagcagaaagtagtgaagctggacccatctcagcctgccttgggaaacctcacc
ccagtggtgctggggccggaagagctctggcctactcggctcaggccagaggttctcaca
ccagaaacacccaggccggtggacattggttctggcagagctcatgatgtctgtactcca
gggaagatcgagagacatgcagatatggcatacaccctggactcggatccctgtggccac
tgcctcatcatcaacaacgtgaacttctgcccttcctcagggctcagcacacgcattggc
tcccacgtggactgtgagaagcttcagcaccgcttctgctggctgcgcttcatggtggag
gtgaagaacgacctgactgctaagaaaatggtcacggctttgatggagatggcgcaccgc
gaccaccgtgccctggactgcttcgtggtggtcatcctctctcatggctgccaggccagc
cacctccagttcccgggtgctgtctatggcacagatggatgctctgtgtccatcgagaga
attgtgaacatcttcaatgggaccggctgccccagcctgggagggaagcccaagctgttc
ttcatccaggcctgtggtggtgagcagaaagaccatggctttgaggtggccttcacttcc
tctcaagacaaggccttcgacagtgactctgagccagatgctgtcccataccaggaaggc
ccaaggaccttggaccagctggacgcagtgtcaagtttgcccacccccagtgacatcctt
gtgtcctactccaccttcccaggttttgtctcctggagagacaagaagagcggttcctgg
tacatcgagaccttggatggtgtcctggagcagtgggctcgctcggaagacctgcagtcc
ctccttctcagggtcgccaatgctgtttctgagaaaggggtttataagcagattcctggc
tgttttaacttcctccggaagaagctgttctttaaaacttcatga

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