KEGG   Rattus norvegicus (rat): 60352Help
Entry
60352             CDS       T01003                                 

Gene name
Mapk12, Sapk3
Definition
mitogen-activated protein kinase 12 (EC:2.7.11.24)
Orthology
K04441  
p38 MAP kinase [EC:2.7.11.24]
Organism
rno  Rattus norvegicus (rat)
Pathway
MAPK signaling pathway
Rap1 signaling pathway
FoxO signaling pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Amyotrophic lateral sclerosis (ALS)
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Influenza A
Epstein-Barr virus infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    60352 (Mapk12)
   04010 MAPK signaling pathway
    60352 (Mapk12)
   04370 VEGF signaling pathway
    60352 (Mapk12)
   04668 TNF signaling pathway
    60352 (Mapk12)
   04068 FoxO signaling pathway
    60352 (Mapk12)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    60352 (Mapk12)
  Cellular commiunity
   04550 Signaling pathways regulating pluripotency of stem cells
    60352 (Mapk12)
 Organismal Systems
  Immune system
   04611 Platelet activation
    60352 (Mapk12)
   04620 Toll-like receptor signaling pathway
    60352 (Mapk12)
   04621 NOD-like receptor signaling pathway
    60352 (Mapk12)
   04622 RIG-I-like receptor signaling pathway
    60352 (Mapk12)
   04660 T cell receptor signaling pathway
    60352 (Mapk12)
   04664 Fc epsilon RI signaling pathway
    60352 (Mapk12)
   04670 Leukocyte transendothelial migration
    60352 (Mapk12)
  Endocrine system
   04912 GnRH signaling pathway
    60352 (Mapk12)
   04914 Progesterone-mediated oocyte maturation
    60352 (Mapk12)
   04917 Prolactin signaling pathway
    60352 (Mapk12)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    60352 (Mapk12)
  Nervous system
   04728 Dopaminergic synapse
    60352 (Mapk12)
   04723 Retrograde endocannabinoid signaling
    60352 (Mapk12)
   04722 Neurotrophin signaling pathway
    60352 (Mapk12)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    60352 (Mapk12)
  Development
   04380 Osteoclast differentiation
    60352 (Mapk12)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    60352 (Mapk12)
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    60352 (Mapk12)
  Infectious diseases
   05132 Salmonella infection
    60352 (Mapk12)
   05133 Pertussis
    60352 (Mapk12)
   05152 Tuberculosis
    60352 (Mapk12)
   05164 Influenza A
    60352 (Mapk12)
   05160 Hepatitis C
    60352 (Mapk12)
   05169 Epstein-Barr virus infection
    60352 (Mapk12)
   05145 Toxoplasmosis
    60352 (Mapk12)
   05140 Leishmaniasis
    60352 (Mapk12)
   05142 Chagas disease (American trypanosomiasis)
    60352 (Mapk12)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     60352 (Mapk12)
Protein kinases [BR:rno01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   60352 (Mapk12)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
7q34
AA seq 367 aa AA seqDB search
MSSPPPARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMK
VTGTPPPEFVQKLQSAEAKNYMEGLPELEKKDFASVLTNASPQAVNLLEKMLVLDAEQRV
TAAEALAHPYFESLRDTEDEPKAQKYDDSFDDVDRTLEEWKRVTYKEVLSFKPPRQLGAR
VPKETAL
NT seq 1104 nt NT seq  +upstreamnt  +downstreamnt
atgagctccccgccacccgcccgcaagggcttttaccgccaggaggtgaccaaaacggcc
tgggaggtgcgcgccgtgtaccaggacctgcagcccgttggctctggtgcctatggtgca
gtgtgctctgcagtagacagccgcactggcaacaaggtggccatcaagaagttgtaccgg
cccttccagtcggagctgtttgccaagcgcgcctacagagagttgcgcctcctcaaacac
atgcgccacgagaacgtcattgggctgctggatgtgttcactcccgatgagactctggat
gacttcacagacttctacctggtgatgccattcatgggcactgacctgggcaagctcatg
aagcacgagactctgagtgaagacagaatccagtttcttgtgtatcagatgctgaagggg
ctgaagtatatccacgctgccggcgtcatccacagggacttgaaacctggaaacctggct
gtgaacgaggactgtgagctgaagatcctagattttggccttgccaggcaggcggacagt
gagatgacaggatatgtggtaacccggtggtatcgggcaccagaggtcatcttgaattgg
atgcgttacacacagacagtggacatttggtctgttggctgcatcatggcagagatgatt
actggaaagatcctgttcaaaggcaatgaccacctggaccagctgaaggagatcatgaaa
gtcacagggacaccccctcctgagtttgtacagaagctacagagtgctgaggccaagaac
tacatggaaggcctccctgagttggaaaagaaggattttgcttctgtcctgaccaatgca
agccctcaggccgtgaatctcctggaaaagatgctggtgttggatgcggaacagcgggtg
acagcagctgaggcattagcccacccatactttgagtcccttcgggacactgaggatgag
cccaaggcccagaaatatgatgactcctttgatgacgtagaccgcacccttgaggaatgg
aagcgtgttacgtataaggaagtgctcagcttcaagcctcccaggcagctaggagccaga
gttccaaaggagacagctctgtga

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