KEGG   Rattus norvegicus (rat): 60664Help
Entry
60664             CDS       R.norvegicus                           
Gene name Pik3r3
Definition phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
Orthology K02649  phosphoinositide-3-kinase, regulatory subunit
Pathway rno04012  ErbB signaling pathway
rno04062  Chemokine signaling pathway
rno04070  Phosphatidylinositol signaling system
rno04150  mTOR signaling pathway
rno04210  Apoptosis
rno04370  VEGF signaling pathway
rno04510  Focal adhesion
rno04620  Toll-like receptor signaling pathway
rno04630  Jak-STAT signaling pathway
rno04650  Natural killer cell mediated cytotoxicity
rno04660  T cell receptor signaling pathway
rno04662  B cell receptor signaling pathway
rno04664  Fc epsilon RI signaling pathway
rno04666  Fc gamma R-mediated phagocytosis
rno04670  Leukocyte transendothelial migration
rno04722  Neurotrophin signaling pathway
rno04810  Regulation of actin cytoskeleton
rno04910  Insulin signaling pathway
rno04914  Progesterone-mediated oocyte maturation
rno04930  Type II diabetes mellitus
rno04960  Aldosterone-regulated sodium reabsorption
rno05200  Pathways in cancer
rno05210  Colorectal cancer
rno05211  Renal cell carcinoma
rno05212  Pancreatic cancer
rno05213  Endometrial cancer
rno05214  Glioma
rno05215  Prostate cancer
rno05218  Melanoma
rno05220  Chronic myeloid leukemia
rno05221  Acute myeloid leukemia
rno05222  Small cell lung cancer
rno05223  Non-small cell lung cancer
Class Environmental Information Processing; Signal Transduction; ErbB
signaling pathway [PATH:rno04012]
Environmental Information Processing; Signal Transduction; VEGF
signaling pathway [PATH:rno04370]
Environmental Information Processing; Signal Transduction; Jak-STAT
signaling pathway [PATH:rno04630]
Environmental Information Processing; Signal Transduction;
Phosphatidylinositol signaling system [PATH:rno04070]
Environmental Information Processing; Signal Transduction; mTOR
signaling pathway [PATH:rno04150]
Cellular Processes; Cell Motility; Regulation of actin cytoskeleton
[PATH:rno04810]
Cellular Processes; Cell Growth and Death; Apoptosis [PATH:rno04210]
Cellular Processes; Cell Communication; Focal adhesion
[PATH:rno04510]
Organismal Systems; Immune System; Toll-like receptor signaling
pathway [PATH:rno04620]
Organismal Systems; Immune System; Natural killer cell mediated
cytotoxicity [PATH:rno04650]
Organismal Systems; Immune System; T cell receptor signaling pathway
[PATH:rno04660]
Organismal Systems; Immune System; B cell receptor signaling pathway
[PATH:rno04662]
Organismal Systems; Immune System; Fc epsilon RI signaling pathway
[PATH:rno04664]
Organismal Systems; Immune System; Fc gamma R-mediated phagocytosis
[PATH:rno04666]
Organismal Systems; Immune System; Leukocyte transendothelial
migration [PATH:rno04670]
Organismal Systems; Immune System; Chemokine signaling pathway
[PATH:rno04062]
Organismal Systems; Endocrine System; Insulin signaling pathway
[PATH:rno04910]
Organismal Systems; Endocrine System; Progesterone-mediated oocyte
maturation [PATH:rno04914]
Organismal Systems; Excretory System; Aldosterone-regulated sodium
reabsorption [PATH:rno04960]
Organismal Systems; Nervous System; Neurotrophin signaling pathway
[PATH:rno04722]
Human Diseases; Cancers; Pathways in cancer [PATH:rno05200]
Human Diseases; Cancers; Colorectal cancer [PATH:rno05210]
Human Diseases; Cancers; Pancreatic cancer [PATH:rno05212]
Human Diseases; Cancers; Glioma [PATH:rno05214]
Human Diseases; Cancers; Acute myeloid leukemia [PATH:rno05221]
Human Diseases; Cancers; Chronic myeloid leukemia [PATH:rno05220]
Human Diseases; Cancers; Melanoma [PATH:rno05218]
Human Diseases; Cancers; Renal cell carcinoma [PATH:rno05211]
Human Diseases; Cancers; Prostate cancer [PATH:rno05215]
Human Diseases; Cancers; Endometrial cancer [PATH:rno05213]
Human Diseases; Cancers; Small cell lung cancer [PATH:rno05222]
Human Diseases; Cancers; Non-small cell lung cancer [PATH:rno05223]
Human Diseases; Metabolic Diseases; Type II diabetes mellitus
[PATH:rno04930]
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Pfam: SH2 DUF662 IncA
PROSITE: SH2
Motif
Other DBs NCBI-GI: 11559994
NCBI-GeneID: 60664
RGD: 621042
RATMAP: ENSRNOG00000000145
Ensembl: ENSRNOG00000000145
UniProt: Q63789
Position 5q36
AA seq 461 aa AA seqDB search
MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPVTSAVTNGMKDCFVSL
QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
NYGFSEPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKN
LQEFHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKDY
IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKVRLEQDLKKQALDNREIDKKMNSIKP
DLIQLRKIRDQHLVWLNHRGVRQRRLNAWLGIKSEDTDESYFINEDDESLPHYDEKTWFV
EDVNRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKPCVIYSPARGYGFAEPYN
LYGSLKELVLHYQQTSLVQHNDSLNVTLAYPVHAQMPSLCR
NT seq 1386 nt NT seq  +upstreamnt  +downstreamnt
atgtacaatacggtgtggagtatggaccgcgatgacgcagactggagggaggtgatgatg
ccctattcgacagaactgatattttatattgaaatggatcctccagctcttccaccaaag
ccacctaagccagtgacgtcagcagttacaaacggaatgaaggactgtttcgtttctctt
caagatgcagagtggtactggggagacatttccagggaagaggtaaatgacaaattgcgg
gacatgccagacggtactttcttagttcgagatgcctcaacaaaaatgcagggagactat
acactgactttgaggaagggaggaaataataaattaataaagatctatcatcgggatggt
aattatggcttttctgagcccctgacgtttaattctgtggtggagctcattaaccactat
caccatgaatctctcgctcagtacaatcccaaacttgatgtgaagctgatgtacccagtg
tccagataccaacaggatcagttggtaaaagaagataacattgatgcggtaggtaaaaac
ctgcaagaattccactctcagtaccaggagaagagtaaagagtacgataggctgtatgaa
gagtacaccaggacgtcacaggaaatacaaatgaagagaactgccattgaagcctttaat
gaaacgattaaaatatttgaggagcagtgtcatacccaagaacaacacagtaaagactat
attgagcggtttcgcagagaggggaatgagaaggagattgagcggattatgatgaattac
gataaattgaaatcccgtctgggtgagattcacgatagcaaagtgcgtcttgagcaggac
ttgaagaaacaagctttggacaaccgggaaatagataaaaaaatgaatagcatcaagcct
gacctgatccagctgcgtaagatccgagaccagcacctcgtatggctcaatcacagggga
gtgaggcagaggcgcctgaacgcctggctggggatcaagagtgaggacacagatgagagc
tattttatcaatgaggacgatgagagcctcccgcattatgatgagaagacctggtttgtg
gaggatgtgaaccgagtacaggcagaggacctgctttatgggaagccagacggtgcattc
ttaattcgtgagagtagcaagaaaggatgttacgcttgttctgtggttgcagacggggag
gtgaagccctgtgtcatctacagccctgctcgaggatatggctttgcagaaccctacaac
ctgtacggctcgctgaaggagctggtgctccactaccagcagacatccctggtccagcac
aacgactccctcaacgtcacgctcgcctaccctgtccacgcacagatgccctcgctctgc
agataa
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