KEGG   Rattus norvegicus (rat): 78975Help
Entry
78975             CDS       T01003                                 

Gene name
Prkaa2, Ampk, Ampka2
Definition
protein kinase, AMP-activated, alpha 2 catalytic subunit (EC:2.7.11.1 2.7.11.27 2.7.11.31)
Orthology
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
rno  Rattus norvegicus (rat)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    78975 (Prkaa2)
   04151 PI3K-Akt signaling pathway
    78975 (Prkaa2)
   04152 AMPK signaling pathway
    78975 (Prkaa2)
   04150 mTOR signaling pathway
    78975 (Prkaa2)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    78975 (Prkaa2)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    78975 (Prkaa2)
   04920 Adipocytokine signaling pathway
    78975 (Prkaa2)
   04921 Oxytocin signaling pathway
    78975 (Prkaa2)
  Environmental adaptation
   04710 Circadian rhythm
    78975 (Prkaa2)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    78975 (Prkaa2)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    78975 (Prkaa2)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     78975 (Prkaa2)
Protein kinases [BR:rno01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   78975 (Prkaa2)
Mitochondrial biogenesis [BR:rno03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    78975 (Prkaa2)
  Mitophagy factors
   Other mitophagy factors
    78975 (Prkaa2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
5q34
AA seq 552 aa AA seqDB search
MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGK
IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLF
QQILSAVDYCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
IATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPTGSFMDDMAMHIP
PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
SGSSTPQRSCSAAGLHRPRSSVDSSTAENHSLSGSLTGSLTGSTLSSASPRLGSHTMDFF
EMCASLITALAR
NT seq 1659 nt NT seq  +upstreamnt  +downstreamnt
atggctgagaagcagaagcacgacgggcgtgtgaagatcggacactacgtgctgggggac
accctgggcgtcggcaccttcggcaaagtgaagattggagaacatcaattgacaggccat
aaagtggcagttaagatcttaaatagacagaagattcgcagtttagatgttgttggaaaa
ataaaacgagaaattcaaaatcttaaactctttcgtcatcctcatattatcaaactctac
caagtgatcagcactccaacagacttttttatggtaatggaatatgtgtctggaggtgaa
ttgttcgactacatctgtaaacacgggagggttgaagaggtggaagctcgccggctcttc
cagcagattctgtctgccgtggactactgtcacaggcacatggttgtccacagggacctg
aagccagagaacgtgttgctggacgcccagatgaatgctaagatagctgacttcggactc
tctaatatgatgtcagatggtgaatttctacgaactagctgtggatcgccaaattatgca
gcaccggaggtcatctcaggaaggctgtatgcgggtcctgaggttgatatctggagctgt
ggtgttatcctgtatgcccttctctgtggcaccctcccgttcgacgatgagcacgtgcct
acgctctttaagaagatccgagggggtgtgttctacatcccggagtatctcaaccgttct
attgccactctgctgatgcacatgctgcaggtggaccccttgaagcgagcaactatcaaa
gacatacgagagcatgaatggtttaaacaggatttgcccagttacctctttcctgaagac
ccctcctatgatgctaacgtcattgatgatgaggctgtgaaagaagtatgtgaaaaattt
gagtgtacagaatcagaagtgatgaacagtttatacagtggtgaccctcaagaccagctc
gcagtggcttatcatctcatcattgacaatcggagaataatgaaccaagccagtgagttc
tacctcgcctccagtcctccaacgggttccttcatggacgatatggccatgcacattccc
cccggcctgaaaccacatcctgaaaggatgccacctctcatagcagacagccccaaagca
cgctgtccactggatgcactcaacacaactaagcccaaatctttagctgtgaaaaaagcc
aagtggcaccttgggatccgaagccagagcaaaccatacgacattatggcggaggtgtac
cgagctatgaagcagctggactttgaatggaaggtagtgaatgcataccatcttcgagta
agaagaaaaaacccagtgactggcaattacgtgaaaatgagcttacagctttacctggtt
gacaatcggagctatcttctagactttaaaagcatcgatgatgaggtggtggagcagagg
tctggttcttcaacacctcagcgctcctgttctgctgccggcctccacagacctcggtca
agtgtcgattccagcacagccgagaaccattcactgtctggctctctcactggttctttg
actggcagcactttgtcctccgcttccccgcgcctgggcagtcataccatggattttttt
gaaatgtgcgccagtcttatcactgctttagcccgttga

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