KEGG   Rattus norvegicus (rat): 81649Help
Entry
81649             CDS       T01003                                 

Gene name
Mapk14, CRK1, CSBP, CSPB1, Csbp1, Csbp2, Exip, Hog, Mxi2, Prkm14, Prkm15, RK, Sapk2A, p38, p38Hog, p38alpha
Definition
mitogen activated protein kinase 14 (EC:2.7.11.24)
Orthology
K04441  
p38 MAP kinase [EC:2.7.11.24]
Organism
rno  Rattus norvegicus (rat)
Pathway
MAPK signaling pathway
Rap1 signaling pathway
FoxO signaling pathway
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Amyotrophic lateral sclerosis (ALS)
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Influenza A
Epstein-Barr virus infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    81649 (Mapk14)
   04010 MAPK signaling pathway
    81649 (Mapk14)
   04370 VEGF signaling pathway
    81649 (Mapk14)
   04668 TNF signaling pathway
    81649 (Mapk14)
   04068 FoxO signaling pathway
    81649 (Mapk14)
 Cellular Processes
  Cellular commiunity
   04550 Signaling pathways regulating pluripotency of stem cells
    81649 (Mapk14)
 Organismal Systems
  Immune system
   04611 Platelet activation
    81649 (Mapk14)
   04620 Toll-like receptor signaling pathway
    81649 (Mapk14)
   04621 NOD-like receptor signaling pathway
    81649 (Mapk14)
   04622 RIG-I-like receptor signaling pathway
    81649 (Mapk14)
   04660 T cell receptor signaling pathway
    81649 (Mapk14)
   04664 Fc epsilon RI signaling pathway
    81649 (Mapk14)
   04670 Leukocyte transendothelial migration
    81649 (Mapk14)
  Endocrine system
   04912 GnRH signaling pathway
    81649 (Mapk14)
   04914 Progesterone-mediated oocyte maturation
    81649 (Mapk14)
   04917 Prolactin signaling pathway
    81649 (Mapk14)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    81649 (Mapk14)
  Nervous system
   04728 Dopaminergic synapse
    81649 (Mapk14)
   04723 Retrograde endocannabinoid signaling
    81649 (Mapk14)
   04722 Neurotrophin signaling pathway
    81649 (Mapk14)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    81649 (Mapk14)
  Development
   04380 Osteoclast differentiation
    81649 (Mapk14)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    81649 (Mapk14)
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    81649 (Mapk14)
  Infectious diseases
   05132 Salmonella infection
    81649 (Mapk14)
   05133 Pertussis
    81649 (Mapk14)
   05152 Tuberculosis
    81649 (Mapk14)
   05164 Influenza A
    81649 (Mapk14)
   05160 Hepatitis C
    81649 (Mapk14)
   05169 Epstein-Barr virus infection
    81649 (Mapk14)
   05145 Toxoplasmosis
    81649 (Mapk14)
   05140 Leishmaniasis
    81649 (Mapk14)
   05142 Chagas disease (American trypanosomiasis)
    81649 (Mapk14)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     81649 (Mapk14)
Protein kinases [BR:rno01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   81649 (Mapk14)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
20p12
AA seq 360 aa AA seqDB search
MSQERPTFYRQELNKTVWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG
TPPAYLINRMPSHEARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt NT seq  +upstreamnt  +downstreamnt
atgtcgcaggagaggcccacgttctaccggcaggagctgaacaagaccgtctgggaggtg
cccgagcgataccagaacctgtccccggtgggctcgggagcctacggctcggtgtgtgct
gcttttgatacaaagacgggacatcgtgtggcagtgaagaagctgtcgagaccgtttcag
tccatcattcacgccaaaaggacctacagggagctgcggctgctgaagcacatgaagcac
gagaatgtgattggtctgttggatgtgtttacacctgcaaggtccctggaggaattcaac
gatgtgtacctggtgacccatctcatgggggcagacctgaacaacatcgtgaagtgtcag
aagcttaccgatgaccacgttcagtttcttatctaccagatcctgcgagggctgaagtat
atacactcggctgacataatccacagggacctaaagcccagcaacctcgctgtgaatgaa
gactgtgagctgaagattctggattttgggctggctcggcacactgatgacgaaatgacc
ggctacgtggctacccggtggtacagagcccccgagattatgctgaattggatgcactac
aaccagacagtggatatttggtccgtgggctgcatcatggctgagctgttgaccggaaga
acgttgtttcctggtacagaccatattaaccagcttcagcagataatgcgtctgacgggg
acaccccctgcttatctcattaacaggatgccaagccatgaggcaagaaactacattcag
tctctggcccagatgccgaagatgaacttcgcaaatgtatttattggtgccaatcccctg
gctgtcgacctgctggaaaagatgctggttttggactcggataagaggatcacagcagcc
caagctcttgcgcatgcctactttgctcagtaccacgaccctgatgatgagccagtggct
gacccttatgaccagtcctttgaaagcagggacctccttatagacgaatggaagagcctg
acctacgatgaagtcattagctttgtgccaccgccccttgaccaagaagaaatggagtcc
tga

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