KEGG   Rattus norvegicus (rat): 81810Help
Entry
81810             CDS       T01003                                 

Gene name
Tgfbr2, TGF-beta_2, Tgfbr2T
Definition
transforming growth factor, beta receptor 2 (EC:2.7.11.30)
Orthology
K04388  
TGF-beta receptor type-2 [EC:2.7.11.30]
Organism
rno  Rattus norvegicus (rat)
Pathway
MAPK signaling pathway
Cytokine-cytokine receptor interaction
FoxO signaling pathway
Endocytosis
TGF-beta signaling pathway
Osteoclast differentiation
Hippo signaling pathway
Adherens junction
Chagas disease (American trypanosomiasis)
HTLV-I infection
Pathways in cancer
Transcriptional misregulation in cancer
Colorectal cancer
Pancreatic cancer
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    81810 (Tgfbr2)
   04350 TGF-beta signaling pathway
    81810 (Tgfbr2)
   04390 Hippo signaling pathway
    81810 (Tgfbr2)
   04068 FoxO signaling pathway
    81810 (Tgfbr2)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    81810 (Tgfbr2)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    81810 (Tgfbr2)
  Cellular commiunity
   04520 Adherens junction
    81810 (Tgfbr2)
 Organismal Systems
  Development
   04380 Osteoclast differentiation
    81810 (Tgfbr2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    81810 (Tgfbr2)
   05202 Transcriptional misregulation in cancers
    81810 (Tgfbr2)
   05210 Colorectal cancer
    81810 (Tgfbr2)
   05212 Pancreatic cancer
    81810 (Tgfbr2)
   05220 Chronic myeloid leukemia
    81810 (Tgfbr2)
  Infectious diseases
   05166 HTLV-I infection
    81810 (Tgfbr2)
   05142 Chagas disease (American trypanosomiasis)
    81810 (Tgfbr2)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     81810 (Tgfbr2)
Protein kinases [BR:rno01001]
 Serine/threonine protein kinases: TKL group
  TGFBR2 family [OT]
   81810 (Tgfbr2)
Enzyme-linked receptors [BR:rno01020]
 Receptor serine/threonine kinases
  Type II TGF-beta receptor
   81810 (Tgfbr2)
Cytokine receptors [BR:rno04050]
 TGF-beta receptors
  Type II TGF-beta receptor
   81810 (Tgfbr2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
8q32
AA seq 567 aa AA seqDB search
MGRGLLRGLWPLHIVLWTRIASTIPPHVPKSVNSDLMAGDNSGAVKLPQLCKFCDVTLST
CDNQKSCMSNCSVTSICEKPQEVCVAVWRKNDKNITLETVCHDPKFTYHGFTLEDATSPT
CVMKEKKRAGETFFMCSCNTEECNDYIIFNEEYTTSSPDLLLVIIQVTGVSLLPPLGIAI
AVIAIFYCYRVHRQQKLSPSWESSKPRKLMDFSDNCAIILEDDRSDISSTCANNINHNTE
LLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYSSWKTEKDIFSDINLK
HENILQFLTAEERKTEMGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAH
LHSDHTPCGRPKMPIVHRDLKSSNILVRSDLTCCLCDFGLSLGLSPTLSVDDLANSGQVG
TARYMAPEVLESRMNLENMESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSRVRE
HPCVESMKDNVLRDRGRPEIPSFWLNHQGIQIVCETLTECWDHDPEARLTAQCVAERFSE
LEHPDRLSGRSCSQEKIPEDGSLNTTK
NT seq 1704 nt NT seq  +upstreamnt  +downstreamnt
atgggtcgggggctgctccggggcctgtggccgctgcacatcgtcctgtggacgcgcatc
gccagcacgatcccgccgcacgttcccaagtcggttaacagcgatctgatggcgggtgac
aacagcggtgcggtcaagcttccacagctgtgcaagttttgcgacgtgacactgtccact
tgtgacaaccagaagtcttgcatgagcaactgcagcgtcacctccatctgtgagaagccg
caggaagtctgcgtggccgtgtggaggaagaacgacaagaacattactctggagaccgtt
tgccacgaccccaagttcacctaccacggcttcactctggaagatgccacttctcccacg
tgcgtcatgaaggaaaagaaaagggcgggcgagaccttcttcatgtgctcctgtaacaca
gaggagtgtaacgattacatcatctttaatgaagaatacaccaccagcagtcctgacctg
ttgctggtcattatccaagtgacgggcgtcagcctcctgcctccgctggggattgccata
gctgtcattgccatcttctactgttaccgtgtccaccggcagcagaagttgagcccctcc
tgggagagcagcaagccccggaagctcatggatttcagcgacaactgcgccatcatcctg
gaggacgaccgctctgacatcagctctacgtgcgccaacaacatcaaccacaatacggaa
ctgctgcccatcgagctggacacgctggtggggaagggccgcttcgccgaggtctacaag
gccaagctgaagcagaacacttcagagcagtttgagaccgtggctgtcaagatcttcccc
tacgaggaatactcctcgtggaaaacggagaaggacatcttctctgacatcaacctgaaa
cacgagaacatcctgcagttcctgacggccgaggagcggaagacggagatgggcaagcag
tactggctgatcacggcgtttcatgctaagggcaacctgcaggagtacctcactaggcac
gtcatcagctgggaggacctgcggaagctgggcagctccctggcccggggcatcgcccat
ctgcacagtgaccacactccttgtgggaggcccaagatgcccattgttcacagggacctc
aagagctctaacatcctagtaagaagcgatctaacctgttgcctgtgtgacttcgggttg
tccttgggcctgagccctactctgtctgtggatgacctggccaacagcgggcaggtggga
acagcgagatacatggccccggaagttctagaatccaggatgaatttggagaacatggag
tccttcaagcagacggatgtctactccatggctctagtactctgggaaatgacgtcgcgc
tgcaacgctgtgggagaagtgaaagattatgagcccccgtttggttccagagtgcgggag
cacccctgtgtggagagcatgaaagacaacgtgctgagagaccgaggacggcctgaaatc
cccagcttctggctcaaccaccagggcatccagatcgtgtgtgagacactgaccgagtgc
tgggaccacgaccccgaggcccgtctcacagcccagtgtgtggcagagcgcttcagtgaa
ctggagcacccagatagactctccgggaggagctgctcccaggagaagattccagaagac
ggctccctgaacactaccaaatag

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