KEGG   Rattus norvegicus (rat): 84577Help
Entry
84577             CDS       T01003                                 

Gene name
Hdac2
Definition
(RefSeq) histone deacetylase 2
  KO
K06067  
histone deacetylase 1/2 [EC:3.5.1.98]
Organism
rno  Rattus norvegicus (rat)
Pathway
Cell cycle
Longevity regulating pathway - multiple species
Notch signaling pathway
Thyroid hormone signaling pathway
Huntington's disease
Alcoholism
Human papillomavirus infection
Epstein-Barr virus infection
Pathways in cancer
Transcriptional misregulation in cancer
Viral carcinogenesis
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04330 Notch signaling pathway
    84577 (Hdac2)
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    84577 (Hdac2)
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    84577 (Hdac2)
  Aging
   04213 Longevity regulating pathway - multiple species
    84577 (Hdac2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    84577 (Hdac2)
   05202 Transcriptional misregulation in cancers
    84577 (Hdac2)
   05203 Viral carcinogenesis
    84577 (Hdac2)
   05220 Chronic myeloid leukemia
    84577 (Hdac2)
  Neurodegenerative diseases
   05016 Huntington's disease
    84577 (Hdac2)
  Substance dependence
   05034 Alcoholism
    84577 (Hdac2)
  Infectious diseases
   05169 Epstein-Barr virus infection
    84577 (Hdac2)
   05165 Human papillomavirus infection
    84577 (Hdac2)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     84577 (Hdac2)
Chromosome [BR:rno03036]
 Eukaryotic Type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class I HDACs
     84577 (Hdac2)
   HDAC complexes
    Sin3A-HDAC complex
     84577 (Hdac2)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    84577 (Hdac2)
  Chromatin remodeling factors
   NuRD complex
    84577 (Hdac2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
RGD: 
Ensembl: 
UniProt: 
Position
20q12
AA seq 488 aa AA seqDB search
MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKA
TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA
GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAVLELLKYHQRVLYIDIDIHH
GDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQ
IFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLG
GGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYM
EKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEE
FSDSEDEGEGGRRNVADHKKGAKKARIEEDKKEAEDKRTDVKEEDKSKDNSGEKTDTKGA
KSEQLNNP
NT seq 1467 nt NT seq  +upstreamnt  +downstreamnt
atggcgtacagtcaaggaggcggcaagaagaaagtgtgctactattatgacggtgatatc
gggaattattattacggccagggtcatcccatgaagccccataggatccggatgactcat
aacttgcttctaaattatggtttataccgaaaaatggaaatatataggcctcataaggcc
actgctgaagaaatgacaaaataccacagtgatgagtatatcaagtttctacgatcaata
aggccagataacatgtcagagtatagtaagcagatgcagagatttaatgtcggagaagac
tgtccagtgttcgatggactctttgagttttgtcagctctccaccggtggctcagttgct
ggggccgtgaagctgaaccgtcaacagactgacatggctgtcaactgggcgggaggactg
caccacgccaagaagtcagaggcctcaggattctgctacgttaatgacattgtgcttgct
gtcctcgagctactgaaatatcatcagagagtcttatatattgacatagacatccaccat
ggtgatggtgttgaggaagctttttatacaacagatcgcgtgatgaccgtctcattccat
aaatacggagaatactttcctggaacaggagacttgagggatattggtgctggaaaagga
aagtactacgctgtcaactttcccatgagggacggtatagatgacgagtcatatggacag
atatttaagcctataatctcaaaagtgatggagatgtaccagccgagcgcggtggtgctg
cagtgtggcgctgactccctctctggtgacaggctgggctgcttcaacctaactgtcaaa
ggtcacgctaaatgtgtagaagtagtgaaaacttttaacttgccgttgctgatgcttggc
ggaggtggctacacaatccggaatgttgctcgatgttggacgtatgagactgcagttgcc
cttgattgtgaaattcccaatgagttgccatataatgattacttcgagtattttggacca
gacttcaaactgcatattagtccctcaaacatgacaaaccagaacactccagaatatatg
gaaaagataaaacagcgtttatttgaaaatctgcgaatgttaccacatgcgcctggtgtt
caaatgcaagctattccagaagatgctgttcatgaagacagtggtgatgaggatggagaa
gaccctgacaagagaatttctattcgagcatcagacaagcggatagcttgtgatgaagag
ttctcagattctgaggatgaaggtgaaggaggtcgtaggaatgtcgctgatcataagaag
ggagccaaaaaagccaggattgaggaagacaagaaggaggcggaggacaagaggacagat
gttaaggaagaagacaaatccaaggacaatagtggtgagaaaacagacaccaaaggagcc
aaatcagaacaactcaacaacccttga

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