KEGG   Rattus norvegicus (rat): 85384Help
Entry
85384             CDS       T01003                                 

Gene name
Sos2, Sos1
Definition
son of sevenless homolog 2 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
rno  Rattus norvegicus (rat)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    85384 (Sos2)
   04010 MAPK signaling pathway
    85384 (Sos2)
   04012 ErbB signaling pathway
    85384 (Sos2)
   04630 Jak-STAT signaling pathway
    85384 (Sos2)
   04068 FoxO signaling pathway
    85384 (Sos2)
   04151 PI3K-Akt signaling pathway
    85384 (Sos2)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    85384 (Sos2)
  Cellular commiunity
   04510 Focal adhesion
    85384 (Sos2)
   04540 Gap junction
    85384 (Sos2)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    85384 (Sos2)
   04660 T cell receptor signaling pathway
    85384 (Sos2)
   04662 B cell receptor signaling pathway
    85384 (Sos2)
   04664 Fc epsilon RI signaling pathway
    85384 (Sos2)
   04062 Chemokine signaling pathway
    85384 (Sos2)
  Endocrine system
   04910 Insulin signaling pathway
    85384 (Sos2)
   04912 GnRH signaling pathway
    85384 (Sos2)
   04915 Estrogen signaling pathway
    85384 (Sos2)
   04917 Prolactin signaling pathway
    85384 (Sos2)
  Nervous system
   04722 Neurotrophin signaling pathway
    85384 (Sos2)
  Development
   04320 Dorso-ventral axis formation
    85384 (Sos2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    85384 (Sos2)
   05206 MicroRNAs in cancer
    85384 (Sos2)
   05205 Proteoglycans in cancer
    85384 (Sos2)
   05214 Glioma
    85384 (Sos2)
   05221 Acute myeloid leukemia
    85384 (Sos2)
   05220 Chronic myeloid leukemia
    85384 (Sos2)
   05211 Renal cell carcinoma
    85384 (Sos2)
   05215 Prostate cancer
    85384 (Sos2)
   05213 Endometrial cancer
    85384 (Sos2)
   05223 Non-small cell lung cancer
    85384 (Sos2)
  Substance dependence
   05034 Alcoholism
    85384 (Sos2)
  Infectious diseases
   05160 Hepatitis C
    85384 (Sos2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
6q24
AA seq 1333 aa AA seqDB search
MQQAPQPYEFFSEENSPKWRGLLVPALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC
LAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
DIGLVSLCEEEPCSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDKKLFKSSE
IEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQD
ILAPEFNDHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLK
ACSEEQEDRECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCLFYNRQLRSKHLAIKK
MNEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHCQTRLP
GYSSAEYRLKEKFVMRKIQICDKEDACEYKHAFELVSKDENSVIFAAKSAEEKNNWMAAL
ISLHYRSTLDRMLDSVLLKEENEQPLRLPRPDVYRFVVTDSEENIVFEDNLQSRSGIPII
KGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPDPEPTEADKL
ALEKGEQPISADLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERDLELLERLEAFISSV
RGKAMKKWVESIAKIIKRKKQAQANGVSHNITFESPPPPVEWHISRAGQSETFDLMTLHP
IEIARQLTLLESDLYRRVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVE
AENFEERVAVLSRIVEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRVL
DDAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNSDFLKRKGKDLINFSKR
RKVAEITGEIQQYQNQPYCLRTEPEMRRFFENLNPMGLLSEKEFTDYLFNKSHEIEPRNC
KQPPRFPRKSTFSLKSPGIRPNASRHGSTSGTFRGHPTPLEREPYKISFSRIAETELEST
VSAPTSPNTPSTPPVSASSDHSVFLDVDLNSSCGSNTIFAPVLLPHSKSFFSSCGSLHKL
SEEPLVPPPLPPRKKFDHDAPNSKGAMKSDDDPPAIPPRQPPPPKVKPRAPVLTGTFEGP
VPSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHPHRDPDWLRDVSTCPNSP
STPPPTPSPRIPRRCHLPSPSHNNLAHPPAPPVPPRQNSSPHLPKLPPKTYKRELSHPPL
YRLPLFENAETPQ
NT seq 4002 nt NT seq  +upstreamnt  +downstreamnt
atgcagcaggcgccgcagccctacgagttcttcagcgaagagaacagcccgaaatggcgg
ggactgttggtcccggccctgcggaaggttcaggagcaagtgcaccccaccctgtcggct
aacgaagagtctctctattacatcgaagaactcatctttcaactgctcaataagctgtgc
ctggctcaaccgaggactgttcaagatgttgaggaacgagttcaaaagacttttcctcat
cctattgataaatgggcaattgctgatgcacagtctgccatagagaaacgaaaacgaaga
aatcctctcttactacctgtggacaaaatccatccttccttgaaggaagttttggggtat
aaagtggactaccatgtatccctctacattgtggctgtattggagtatatctcagcagat
attttgaaattggctggtaattatgtttttaatatccggcattatgaaatatctcagcaa
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgaccaggatgac
gatataggcttggtttctctctgtgaagaggaaccttgttcttctggtgagctaaactat
tatgaccttgttagaactgaaatcgcagaagaaagacagtatctacgggaactgaatatg
atcattaaagtattccgggaagcctttctttcagacaaaaagttgttcaagtcttctgaa
attgaaaagattttcagtaacatttcagatatacatgaactgactgtgaaacttttaggt
ttgattgaagacacagtagaaatgacagatgaaagcagtcctcacccgctagctggtagc
tgctttgaagatttagcagaggagcaggcttttgacccctatgaaacgttatcacaggac
attcttgctccagagtttaatgaccacttcagcaagttgatggccagacctgcagttgct
ctgcactttcagtccattgctgacggctttaaggaggctgttcgatatgtccttccgcgc
ctcatgctggtgccggtgtatcattgttggcattactttgaattattaaagcagttgaaa
gcatgtagcgaagaacaggaagaccgagagtgtttgaatcaggctatcactgccctcatg
aacctccaaggcagcatggaccggatttacaagcagcactcgccaaggcgccggccaggg
gatcctgtttgccttttttacaatcgtcaattaagaagcaagcacctggctatcaaaaaa
atgaatgaaattcagaaaaacattgatgggtgggaaggcaaagatattggacagtgttgt
aatgagttcataatggaaggaccattgaccagaattggtgctaagcatgaaaggcatatt
ttcctcttcgatggcttaatgatcagctgtaaacccaatcattgccagactcgacttcca
gggtatagtagtgcagaatacaggttaaaagagaagtttgtcatgaggaaaattcaaatc
tgtgataaagaagacgcttgtgaatacaaacatgcttttgaattagtatccaaagatgaa
aacagtgtaatatttgctgccaagtcagctgaagagaaaaacaactggatggcagccctt
atctcccttcactatcggagcactctagatagaatgctggactctgtgttactgaaagag
gagaacgagcagcccctgcggctaccgcggccagacgtgtaccgcttcgtggtgacagac
tcagaggagaacatagtttttgaagacaacttgcaaagcagaagtggaatccccattatt
aaaggaggcaccgtggtgaaactgatcgaaaggctaacatatcacatgtatgcagatccc
aattttgttcgtactttccttactacgtatcgttcattttgtaagccacaggaattgcta
agcttgctgatagaacggtttgaaattccagatccagagcctactgaggccgacaaactg
gcgctagagaaaggcgagcagccaatcagcgcagatctgaaaagattccgcaaggaatat
gtccaacccgtgcaacttagggtcttgaatgtctttcgccactgggttgagcatcatttt
tatgactttgaaagagacttggaattgcttgaaagactggaagccttcatttcaagtgta
agagggaaagccatgaagaagtgggtagaatccattgctaaaatcatcaagaggaagaag
caagctcaggccaatggagtaagccataatatcacctttgaaagtccgcctccaccggtt
gaatggcacataagtagggcgggacagtctgaaacctttgaccttatgacacttcatccc
atagagattgcacggcagttaacactcttggaatctgatctctacaggagagtccagcct
tctgaacttgtagggagtgtctggaccaaagaagataaagaaataaattctccaaatcta
ttaaaaatgattcgccatacaacaaacctcactttgtggtttgaaaaatgcattgtggaa
gcagaaaactttgaagaacgggtggcagtgctcagcagaatagtagaaattctgcaagtg
tttcaagatctgaataatttcaatggcgtgttggagatagtcagtgcagtcaattcagtg
tcagtgtacagactagaccacacatttgaggcattgcaggaaaggaagcggagagttttg
gatgacgctgtggaattaagtcaggatcactttaaaaaatacctagtaaaacttaaatca
atcaatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaa
gaagggaacagcgactttctaaagaggaaagggaaagatttgatcaatttcagtaagagg
agaaaagtggctgaaataaccggagagattcagcagtatcagaaccaaccatactgctta
cggacagaaccagagatgaggagattctttgaaaacctcaatcccatgggacttttatct
gaaaaagagtttacagattatttgttcaacaaatctcatgaaattgaaccccgaaactgc
aaacaaccacctcgatttcctaggaagtcaaccttttccttaaaatctcctggaataagg
cccaatgccagccgccatggctctacctcaggcacgttccgaggtcacccaacccctctg
gaaagggagccttataagataagctttagcaggatcgccgagacggagctagaatccacg
gtgtcagcaccgacatctcccaacaccccatccaccccacctgtgtctgcttcttcagac
cacagcgtgtttctagatgtggacctcaatagctcctgtggcagcaataccatctttgct
ccagtcctcttgccacactcaaagtctttcttcagctcatgtggaagtctacacaaactg
agtgaagagccactagttcctcctccgcttccccctcggaaaaagtttgatcacgatgct
ccgaactccaagggagctatgaaatcggatgatgaccctcctgctattccaccaagacaa
ccccctcctccaaaggtaaagccaagagctcctgtcctcacgggtacatttgaagggcct
gtgcccagtccacctccacctcctcccagagaccctcttcctgatactcctccaccagtt
cctcttcggcctccggaacactttataaactgtccgtttaatctccagccgcctccgctg
ggacatcctcacagagacccagactggctcagagacgttagcacatgccctaattcacca
agcactcctccccctacgccctcgccacggattccacgcagatgccatttgcccagcccc
agtcacaacaatcttgctcaccctccagctcctcccgttccaccaaggcagaattcaagc
cctcacctaccaaaactgccaccaaagacttacaagcgggagctttcacacccgccattg
tacagactacctttgtttgaaaatgcagaaactcctcagtga

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