KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104675499
Entry
104675499         CDS       T03989                                 
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
  KO
K08852  serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro04140  Autophagy - animal
rro04141  Protein processing in endoplasmic reticulum
rro04210  Apoptosis
rro04932  Non-alcoholic fatty liver disease
rro05010  Alzheimer disease
rro05012  Parkinson disease
rro05014  Amyotrophic lateral sclerosis
rro05016  Huntington disease
rro05017  Spinocerebellar ataxia
rro05022  Pathways of neurodegeneration - multiple diseases
rro05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rro00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    104675499 (ERN1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    104675499 (ERN1)
  09143 Cell growth and death
   04210 Apoptosis
    104675499 (ERN1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    104675499 (ERN1)
   05012 Parkinson disease
    104675499 (ERN1)
   05014 Amyotrophic lateral sclerosis
    104675499 (ERN1)
   05016 Huntington disease
    104675499 (ERN1)
   05017 Spinocerebellar ataxia
    104675499 (ERN1)
   05022 Pathways of neurodegeneration - multiple diseases
    104675499 (ERN1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    104675499 (ERN1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    104675499 (ERN1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rro01001]
    104675499 (ERN1)
Enzymes [BR:rro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     104675499 (ERN1)
Protein kinases [BR:rro01001]
 Serine/threonine kinases: Other
  IRE family
   104675499 (ERN1)
SSDB
Motif
Pfam: Pkinase Ribonuc_2-5A PK_Tyr_Ser-Thr PQQ_2 PQQ Pkinase_fungal Kdo APH CytochromB561_N
Other DBs
NCBI-GeneID: 104675499
NCBI-ProteinID: XP_030778818
Position
19:complement(77403621..77494985)
AA seq 979 aa
MPARRLLLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKE
DPVLQVPTHVEEPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSSDGILYM
GKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNAT
YFDYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLR
KVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPS
MVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKSKNKLNYLRNY
WLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTV
SRDVEEKPAHAPARPEAPVDSVLKDVATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQ
FQKELEKIQLLQQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPNTSPRASNHSLC
SGSSASKAGSSPSLEQDDGDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAV
KRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDF
AHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKL
AAGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKS
LQRQANILLGACSLECLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQ
LQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVR
DLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQ
PYYFHRLPEPQPPVTPDAL
NT seq 2940 nt   +upstreamnt  +downstreamnt
atgccggcccggcggctgctgctgctgctgctgctgacgctactgctgcccggcctcggg
atttttggaagtaccagcacagtgacgcttcctgaaaccttgttgtttgtgtcaacgctg
gatggaagtttgcatgctgtcagcaagaggacaggctcaatcaaatggactttaaaagaa
gatccagtcctacaggtcccaacgcatgtggaagagcctgcctttctcccagatcctaat
gatggcagcctgtatacgcttggaagcaagaataatgaaggcctgacgaaacttcctttt
accatcccagaattggtgcaggcatctccgtgccgaagttcagatggaatcctctacatg
ggtaaaaagcaggacatctggtatgttattgacctcctgactggggagaagcagcagacc
ttgtcatcagcctttgcagatagtctctgcccatcaacctctcttctgtatcttgggcga
acagaatacaccatcaccatgtacgacaccaaaacccgagagctccggtggaatgccacc
tactttgactacgcagcctcactgcccgaggacgacatggactacaagatgtcccacttt
gtgtccaatggtgatgggctggtggtgaccgtggacagtgaatctggggatgtcctgtgg
atccaaaactacgcctcccctgtggtggccttttatgtatggcagcgggagggtctcagg
aaggtgatgcacatcaatgtcgctgtggagaccctgcgctatctgaccttcatgtctggg
gaggtggggcgcatcaccaagtggaagtacccgttccccaaggagacagaggccaagagc
aagctgacgcccactctgtatgttgggaaatactctaccagcctctatgcctctccctca
atggtacacgagggagttgctgtcgtgccccgcggcagcacacttcctttgctggaaggg
ccccagactgatggcgtcaccattggggacaagggggagtgtgtgatcacgcccagcaca
gacctcaagtttgatcccggactcaaaagcaagaacaagctcaactacttgaggaattac
tggcttctgataggccaccatgaaaccccactgtctgcgtctaccaagatgctggagaga
ttccccaacaatctgcccaaacatcgggaaaatgtgattcctgctgattcagagaaaaag
agctttgaggaagttatcaacctggttgaccagacttcagaaaacgcacctaccaccgtg
tctcgggatgtggaggagaagcccgcccatgcccctgcccggcccgaggcccccgtggac
tccgtgctcaaggacgtggccaccatcatcctgagcaccttcctgctgattggctgggtg
gccttcatcatcacctaccccctgagcatgcatcagcagcagcagctccagcaccagcag
ttccagaaggaactggagaagattcagctcctgcagcagcagcagcagcagctacccttc
cacccacctggagacacggctcaggacggcgagcttctggacacatctggcccatactca
gagagctcgggcaccagcagccccaacacgtcccccagggcctccaaccactcgctctgc
tccggcagctctgcctccaaggctggcagcagcccctccctggagcaagacgacggagat
gaggaaaccagcatggtgatagttgggaaaatttccttctgtcccaaggacgtcctgggc
catggagctgagggcacaattgtgtaccggggcatgtttgacaaccgtgatgtggccgtg
aagaggatcctccccgagtgttttagcttcgcagaccgtgaggtccagctgttgcgagaa
tcagatgagcacccgaacgtgatccgctacttctgcacggagaaggaccggcaattccag
tacattgccatcgagctgtgtgcagccaccctgcaagagtatgtggagcagaaggacttt
gcgcatctcggcctggagcccatcaccttgctgcagcagaccacctcgggcctggcccac
cttcactccctcaacatcgttcacagagacctaaagccccacaacattctcatatccatg
cccaatgcacatggcaagatcaaggccatgatctctgactttggcctgtgcaagaagctg
gcagcgggcaggcacagcttcagccgccgatctggggtgcctggcacagaaggctggata
gctccagagatgctgagcgaagactgtaaggagaaccctacctacacggtggacatcttt
tctgcaggctgcgtcttttactacgtgatctctgagggcagccacccttttggcaagtcc
ctgcagcggcaggccaacatcctcctgggtgcctgcagcctcgagtgcttgcacccagag
aagcacgaagacgtcattgcacgtgaattgatagagaagatgattgcgatggatcctcag
aaacgcccctcagcgaagcacgtgctgaaacacccattcttctggagcctagagaagcag
ctccagttcttccaggacgtgagtgacagaatagaaaaggaatccctggatggcccgatt
gtgaaacagttagagagaggcgggagagccgtggtgaagatggactggcgggagaacatc
accgtccccctccagacagacctgcgtaaattcaggacctataaaggtggttctgtcaga
gatctcctccgagccatgagaaataagaagcaccactaccgggaactgcctgcagaggtg
cgggagacgctggggtccctccctgatgacttcgtgtgctacttcacgtctcgcttcccc
cacctcctcgcacacacctaccgggccatggagctgtgcagccacgagagactcttccag
ccctactacttccacaggctcccagagccccagcccccagtgactccagatgccctctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (11)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (9)   
   Pfam (9)   
All databases (33)   

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