KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104679498Help
Entry
104679498         CDS       T03989                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:rro00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    104679498 (INSR)
   04015 Rap1 signaling pathway
    104679498 (INSR)
   04010 MAPK signaling pathway
    104679498 (INSR)
   04066 HIF-1 signaling pathway
    104679498 (INSR)
   04068 FoxO signaling pathway
    104679498 (INSR)
   04072 Phospholipase D signaling pathway
    104679498 (INSR)
   04022 cGMP - PKG signaling pathway
    104679498 (INSR)
   04151 PI3K-Akt signaling pathway
    104679498 (INSR)
   04152 AMPK signaling pathway
    104679498 (INSR)
   04150 mTOR signaling pathway
    104679498 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    104679498 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    104679498 (INSR)
   04923 Regulation of lipolysis in adipocyte
    104679498 (INSR)
   04913 Ovarian Steroidogenesis
    104679498 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    104679498 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    104679498 (INSR)
   04213 Longevity regulating pathway - multiple species
    104679498 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    104679498 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    104679498 (INSR)
   04931 Insulin resistance
    104679498 (INSR)
Enzymes [BR:rro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     104679498 (INSR)
Protein kinases [BR:rro01001]
 Receptor tyrosine kinases
  INSR family [OT]
   104679498 (INSR)
Cytokine receptors [BR:rro04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   104679498 (INSR)
CD molecules [BR:rro04090]
 Proteins
  104679498 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
Un
AA seq 1396 aa AA seqDB search
MGTLQRKPLIPAGCRVYRARDENTGPRFHVHEASSAPILLTHPPCVCSPVFAYCSFSLLV
CPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVY
GLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCY
LATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSH
CQKVCPTICKSHGCTAEGLCCHSECLGNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYH
FQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGP
CPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGY
LKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLF
FHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILL
RWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQN
HPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNS
SSQIILKWKPPSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFESEDS
QKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRPSRKRRSLGD
IGNVTAAVPTVAAFPNTSSTSTPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACN
QDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNIVHLMWQEPKEPNGLIVLYEV
SYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTD
YLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVF
PCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLR
ERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNP
GRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYE
TDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVL
KFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHS
EENKAPESEELEMEFEDMENVPLDRSSHCQREEAGGRDGGSSLGFKRSYEEHIPYTHMNG
GKKNGRILTLPRSNPS
NT seq 4191 nt NT seq  +upstreamnt  +downstreamnt
atgggcactttacagagaaaaccactcatcccggctggctgcagggtttacagggcccgg
gatgaaaacacagggcccaggtttcacgtccatgaggccagttctgccccgatccttctg
acgcatccaccgtgcgtctgctcacctgtctttgcttactgttcattttctcttctagtg
tgtcctggcatggatatccggaacaacctcaccaggttacacgagctggagaattgctct
gtcattgaaggacacttgcagatactcttgatgttcaaaacgaggcccgaagatttccga
gacctcagtttccccaaactcataatgatcactgattacttgctgctcttccgggtctat
gggcttgagagcctgaaggacctgttccccaacctcacggtcatccggggatcacgactg
ttctttaactacgcgctggtcatcttcgagatggttcacctcaaggaactcggcctctac
aacctaatgaacatcacccggggttctgtccgcattgagaagaacaacgagctctgttac
ttggccactatcgactggtcccgcatcctggattccgtggaggataattacatcgtgttg
aacaaagatgacaacgaggagtgcggagacatctgtccgggtacagcgaagggcaagacc
aactgccccgccaccgtcatcaatgggcagtttgtcgaacggtgttggactcatagtcac
tgccagaaagtttgcccaaccatctgtaagtcacacggctgcactgccgaaggcctctgt
tgccacagcgagtgcctgggcaactgttctgagcccgacgaccccaccaagtgcgtggcc
tgccgcaacttctacctggacggcaggtgtgtggagacctgcccgcccccgtactaccac
ttccaggactggcgctgtgtgaacttcagcttctgccaggacctgcaccacaaatgcaag
aactcgcggaggcagggctgccaccagtacgtcattcataacaacaagtgcatccctgag
tgtccctccgggtacacgatgaattccagcaacttgctgtgcaccccgtgcctgggcccc
tgtcccaaggtatgccacctcctagaaggcgagaagaccatcgactcggtgacgtctgcc
caggagctccgaggatgcactgtcatcaacgggagtctgatcatcaacattcgaggaggc
aataatctggcagctgagctagaagccaacctcggcctcattgaagaaatttcagggtat
ctaaaaatccgccgatcctacgctctggtgtcactttccttcttccggaagttacgtctg
attcgaggagagaccttggaaatcgggaactactccttctatgccttggacaaccagaac
ctaaggcagctctgggattggagcaaacacaacctcaccatcactcaggggaaactcttc
ttccactataaccccaaactctgcttgtcagaaatccacaagatggaagaagtttcagga
accaaggggcgccaggagagaaatgacattgccctgaagaccaatggggaccaggcatcc
tgtgaaaatgagttacttaaattttcttacattcggacatctttcgataagatcttgctg
agatgggagccgtactggccccccgacttccgagacctcctggggttcatgctgttctac
aaagaggccccttaccagaatgtgacggagtttgacgggcaggatgcgtgtggttccaac
agttggacggtggtagacattgacccgcccctgaggtccaacgaccccaaatcacagaac
cacccaggatggctaatgcggggtctcaagccctggacccagtatgccatctttgtgaag
accctggtcaccttttcggatgaacgccggacctacggggccaagagtgacatcatttat
gtccagacagatgctaccaacccctccgtgcccctggatccaatctcagtatctaactca
tcatcccagattattttgaagtggaaacccccctctgaccccaacggcaacatcacccac
tacctggttttctgggagaggcaggcggaagacagtgagctgttcgagctggattattgc
ctcaaagggctgaagctgccctctaggacctggtctccaccattcgagtctgaagattct
cagaagcacaaccagagtgaatatgaggattcagccggtgaatgttgctcgtgtccaaag
acagactctcagatcctgaaggagctggaggagtcctcgtttcggaagacgtttgaggat
tacctgcacaacgtggttttcgtccccaggccatctcggaaacgcaggtcccttggcgat
attgggaatgtgacggcggctgtgcccacggtggcagctttccccaacacttcctcgacc
agcacgcccacgagtccggaggagcacaggccctttgagaaggtggtgaacaaggagtcg
ctggtcatctccggcttgcgacacttcacgggctatcgcatcgagctgcaggcttgcaac
caagacacccctgaggaacggtgcagtgtggcagcctacgtcagcgccaggaccatgcct
gaagccaaggctgatgacattgttggccctgtgacgcacgaaatctttgagaacaacatc
gtccacttgatgtggcaggagccgaaggagcccaatggtctgatcgtgctgtatgaagtg
agttatcggcgatatggcgatgaggagctgcatctctgtgtctcccgcaagcacttcgct
ctggaacggggctgcaggctgcgcgggctgtctccagggaactacagcgtgcgagtccgg
gccacctccctcgcgggcaacggctcctggacggaacccacctatttctacgtcacagac
tatttagatgtcccgtcaaatattgcaaaaattatcatcggccccctcatctttgtcttt
ctcttcagtgttgtgattggaagtatttatctattcctgagaaagaggcagccagatggg
ccactgggaccgctttacgcttcttcaaaccctgagtatctcagtgccagtgatgtgttt
ccatgctctgtgtacgtgccggacgagtgggaggtgcctcgagagaagatcaccctcctt
cgagagctggggcagggctcctttggtatggtgtatgagggcaacgccagggacatcatc
aagggtgaggcagagacccgcgtggcagtgaagacggtcaacgagtcagccagtctccga
gagcggattgagttcctcaatgaggcctcggtcatgaagggcttcacctgccatcatgtg
gtgcgcctcctgggagtggtgtccaagggccagcccacgctggtggtgatggagctgatg
gctcacggagacctgaagagctacctccgttctctgcggccagaggctgagaataatcct
ggccgccctccccctaccctgcaagagatgattcagatggcagcggagattgctgatggg
atggcctacctgaatgccaagaagtttgtgcatcgggacctggcagcaagaaactgcatg
gttgcccatgattttactgtcaaaattggagactttggaatgaccagagacatctatgaa
actgattactaccggaaagggggcaagggtctgctccctgtacggtggatggcgccggag
tccctgaaggatggggtctttaccacttcttctgacatgtggtcctttggcgtggtcctt
tgggaaatcaccagcttggcagaacagccttaccaaggcctgtctaatgaacaggtgttg
aaatttgtcatggacggagggtacctggatcaacctgacaactgtccagagagagtcact
gacctcatgcgcatgtgctggcaattcaaccccaagatgaggccaaccttcctggagatt
gtcaacctgctcaaagacgacctgcaccccagctttccggaggtgtccttctttcacagc
gaggagaacaaggcccccgagagtgaggagctggagatggagtttgaggacatggagaat
gtgccgctggaccgttcctcgcactgtcagagggaggaggcggggggccgggatggaggg
tcctcgctaggtttcaagcggagctacgaggaacacatcccttacactcacatgaacgga
ggcaagaaaaacgggcggatcctgaccttgcctcggtccaatccttcctaa

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