KEGG   Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101028986Help
Entry
101028986         CDS       T04350                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor isoform X3
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
sbq  Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:sbq00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    101028986 (INSR)
   04015 Rap1 signaling pathway
    101028986 (INSR)
   04010 MAPK signaling pathway
    101028986 (INSR)
   04066 HIF-1 signaling pathway
    101028986 (INSR)
   04068 FoxO signaling pathway
    101028986 (INSR)
   04072 Phospholipase D signaling pathway
    101028986 (INSR)
   04022 cGMP - PKG signaling pathway
    101028986 (INSR)
   04151 PI3K-Akt signaling pathway
    101028986 (INSR)
   04152 AMPK signaling pathway
    101028986 (INSR)
   04150 mTOR signaling pathway
    101028986 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    101028986 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    101028986 (INSR)
   04923 Regulation of lipolysis in adipocyte
    101028986 (INSR)
   04913 Ovarian Steroidogenesis
    101028986 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101028986 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    101028986 (INSR)
   04213 Longevity regulating pathway - multiple species
    101028986 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    101028986 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    101028986 (INSR)
   04931 Insulin resistance
    101028986 (INSR)
Enzymes [BR:sbq01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     101028986 (INSR)
Protein kinases [BR:sbq01001]
 Tyrosine protein kinases
  InsR family [OT]
   101028986 (INSR)
Enzyme-linked receptors [BR:sbq01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   101028986 (INSR)
Cytokine receptors [BR:sbq04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   101028986 (INSR)
CD molecules [BR:sbq04090]
 Proteins
  101028986 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
Unknown
AA seq 1370 aa AA seqDB search
MGAGGRRGAAAAPLLVAVAALFLGAAGQMYPGEVCPGMDIRNNLSRLHELENCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTSKGKTNCPATVINGQFVERCWTHSHCQKVCPTVCKSHGCTAEGLCCHSECL
GNCSEPGDPTKCVACRNYYLDGRCVDSCPPPYYQFQDWRCVNFSFCQDLHYRCKNSRRQS
CYQYVIHNNRCLPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEREKIIDSVTSAQDLRGC
TVINGSLIINIRGGNNLAVELEANLGLIEEISGYLKIRRSYALVSLAFFRKLRLIRGETL
EAGNYSFYALDNQNLRQLWDWSKHNLTIVQGKLFFHYNPKLCLSEIHKMEEISGTKGRQE
KNDIALKTNGDQASCENELIKFSSIRTSSDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPQRSSDPTSQSHPGWLMRNLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTAATNPSVPLDPISVSNSSSQIILKWKPPTDPNGNITHYLVFWQ
RQVEDSELFELDYCLKGLKLPSRTWSPPVESEGFQKHNQSEEEDLAGECCSCPKTDSQIQ
KELEESSFRKTFEDYLHNVVFIPRPTRKRRSLDDIGNMTEAEPTVAALPNTSLTMEPMSP
EEPKPFEKVVNRESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADD
IVSPVTHEILENNIVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFTLERGCR
LRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVSDYLDVPSNIAKIIIGPLIFVFLFSVVI
GSIYIFLRKRQQDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQG
SFGMVYEGNAKDVIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGV
VSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNA
KKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGI
FTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMEGGYLDQPDNCPERVTDLMRMC
WQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMENVPLDRS
SHCQREETGGRDGGSSLGLKRSYDEHIPYTHMNGGKKNGRILALPRSNPS
NT seq 4113 nt NT seq  +upstreamnt  +downstreamnt
atgggcgccgggggccgccggggggcggcggccgcgccgctgctggtggctgtggccgcg
ctgttcttgggcgccgctggccaaatgtaccccggagaggtgtgccctggcatggatatc
cggaacaatctcagcaggctgcatgagctggagaattgctctgtcatcgaaggacactta
cagatactcttgatgttcaaaacgaggcctgaagatttccgagacctcagtttccccaaa
ctcatcatgatcactgattacttgctgctcttccgggtctatgggctcgagagcctgaaa
gacctgttccccaacctcaccgtcatccggggatcgagactgttcttcaactatgcgctg
gtcatcttcgagatggtgcacctcaaggaactcggcctctacagcctgatgaacatcacc
aggggttctgtccgcattgagaagaacaatgagctctgctacttggccactattgactgg
tcccgtatcctggattccgtggaggacaattacattgtgttgaacaaagatgacaacgag
gagtgtggagacatctgtccaggtacctcgaagggcaagaccaactgccctgccactgtc
atcaacggacagtttgtcgaacggtgttggactcacagtcattgtcagaaagtttgcccg
accgtctgtaagtcacacggctgcaccgcggaaggcctctgttgccacagtgaatgcttg
ggcaactgttccgagcccggtgaccccaccaagtgcgtggcctgccgcaactactacctg
gacggcaggtgtgtggactcctgcccgcccccatactaccagttccaggactggcgctgc
gtgaacttcagcttctgccaggacctgcactacagatgcaagaactcgcggaggcagagc
tgctaccagtacgtcattcacaacaacaggtgtctccccgagtgtccctctgggtacacg
atgaattccagcaacttgatgtgcaccccgtgcctgggtccctgtcccaaggtgtgccac
cttttagaacgcgagaaaatcatcgactcagtgacgtctgcccaggatctccgaggatgc
accgtcatcaatgggagtctgatcatcaacattcgaggaggcaacaatctggcagttgag
ctagaagccaacctcggcctcattgaagaaatttcagggtatctaaaaatccgccgatcc
tacgctctggtatcacttgccttctttcggaagttgcgtctgattcgaggagagaccttg
gaagccgggaactactccttctatgccttggacaatcagaacctaaggcagctctgggac
tggagcaaacacaacctcaccatcgttcaggggaaactcttcttccactataaccccaaa
ctctgcttgtcagaaatccacaagatggaagaaatttcaggaaccaaggggcgccaggag
aagaatgacattgccttaaagaccaatggggaccaagcatcctgtgaaaatgaattaatt
aaattttcttccattcggacgagttctgacaagatcttgctgaaatgggagccgtactgg
ccccctgacttccgagatctcttggggttcatgctgttctacaaagaagccccttatcag
aatgtgacggagttcgacgggcaggatgcttgtggttccaacagttggacggtggtagac
attgacccaccccagaggtccagtgaccccacgtcacagagccacccaggatggctgatg
cggaatctcaagccctggacccagtatgctatctttgtgaagaccctggtcaccttttcc
gatgaacgccggacctatggggccaagagtgacatcatttatgtccagacagctgccacc
aacccgtccgtgccactggatccaatctcagtgtctaactcatcatcccagattattctg
aagtggaaacccccgacggaccccaatggcaacatcacccactacctggttttctggcag
aggcaggtggaagacagtgagctgttcgagttggattattgcctcaaaggattgaagctg
ccctcaaggacgtggtctccaccagttgagtctgaaggttttcagaagcacaaccagagt
gaagaggaggatttggccggcgagtgttgctcctgtccaaagacagactctcagatccag
aaggagctggaggagtcctcgtttaggaagacgtttgaggattacctgcacaatgtcgtt
ttcatccccaggccgactcggaaacgcaggtcccttgatgacattgggaacatgacagag
gccgagcccacggtggcagctctccctaacacttccttgaccatggagcccatgagtccg
gaggagcccaagcccttcgagaaggtggtgaacagagagtcgctggtcatctctggcttg
cgacacttcacgggctatcgcatcgagctgcaggcttgcaaccaagacacccccgaggaa
cggtgcagcgtggcagcctatgtcagcgccaggaccatgcctgaagccaaggctgatgac
atcgtcagccctgtgacccacgaaatccttgagaacaacatcgtccacttgatgtggcag
gagccaaaggaacccaatggtctgatcgtgctgtatgaagtgagttatcggcgatatggc
gatgaggagctgcatctctgtgtctcccgcaagcacttcactctggaacggggctgcagg
ctgcgtgggctgtcgccggggaactacagcgtgcgagttcgggccacttccctagcgggc
aacggctcctggacggaacccacctatttctacgtatcggactacttagatgtcccatca
aatattgcaaaaattatcatcggccccctcatctttgtctttctcttcagcgttgtgatt
ggaagtatttatatattcctgagaaagaggcagcaagatggaccactgggaccactttat
gcttcttcaaaccctgagtatctcagtgccagtgatgtgtttccatgctctgtatacgtg
ccggacgagtgggaggtgcctcgagagaagatcaccctccttcgtgagctgggacagggc
tccttcggcatggtgtatgagggcaatgccaaggacgtcatcaagggtgaggcagagacc
cgtgtggcagtgaagacggtcaacgaatcagccagtctccgagagcgaattgagttcctc
aatgaggcctcagtcatgaagggcttcacctgccatcacgtggtgcgcctcctgggagtg
gtgtccaagggccagcccacgctggtggtgatggagctgatggctcacggagacctgaag
agctacctccgttctctgcggccagaggctgagaacaatcccggccgccctccccccacc
ctgcaagagatgattcagatggcagcagagattgctgacgggatggcttacctgaacgcc
aagaagtttgtgcatcgggacctggcagccagaaactgcatggtcgcccatgatttcact
gtcaaaattggagactttggaatgaccagagacatctatgaaacagattactaccggaaa
gggggcaagggtctgctccctgtgcggtggatggcaccagagtccctgaaggacgggatc
tttaccacttcttctgacatgtggtcctttggcgtggtcctctgggaaatcaccagcttg
gcagaacagccttaccaaggcctgtctaatgaacaagtgctgaagttcgtcatggaagga
gggtatctggatcaacccgacaactgtccagagagagtgaccgatctcatgcgtatgtgc
tggcaattcaaccccaagatgaggccaaccttcctggagattgtcaacttgctcaaggat
gacctgcatcccagctttccggaggtatccttctttcacagcgaggagaacaaggctccc
gagagcgaggagctggagatggagtttgaggatatggagaacgtccccctggatcgttcc
tcccactgtcagagggaggagaccgggggccgggatggagggtcctcactgggtctcaag
cggagctatgacgaacacatcccctacacccacatgaacggaggcaagaagaacgggcgg
attctggccttgcctcggtccaatccttcctaa

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