KEGG   Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101034552
Entry
101034552         CDS       T04350                                 
Symbol
ADCY8
Name
(RefSeq) adenylate cyclase type 8
  KO
K08048  adenylate cyclase 8 [EC:4.6.1.1]
Organism
sbq  Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
sbq00230  Purine metabolism
sbq01100  Metabolic pathways
sbq01522  Endocrine resistance
sbq04015  Rap1 signaling pathway
sbq04020  Calcium signaling pathway
sbq04022  cGMP-PKG signaling pathway
sbq04024  cAMP signaling pathway
sbq04062  Chemokine signaling pathway
sbq04072  Phospholipase D signaling pathway
sbq04114  Oocyte meiosis
sbq04211  Longevity regulating pathway
sbq04213  Longevity regulating pathway - multiple species
sbq04261  Adrenergic signaling in cardiomyocytes
sbq04270  Vascular smooth muscle contraction
sbq04371  Apelin signaling pathway
sbq04540  Gap junction
sbq04611  Platelet activation
sbq04713  Circadian entrainment
sbq04714  Thermogenesis
sbq04720  Long-term potentiation
sbq04723  Retrograde endocannabinoid signaling
sbq04724  Glutamatergic synapse
sbq04725  Cholinergic synapse
sbq04727  GABAergic synapse
sbq04742  Taste transduction
sbq04750  Inflammatory mediator regulation of TRP channels
sbq04911  Insulin secretion
sbq04912  GnRH signaling pathway
sbq04913  Ovarian steroidogenesis
sbq04914  Progesterone-mediated oocyte maturation
sbq04915  Estrogen signaling pathway
sbq04916  Melanogenesis
sbq04918  Thyroid hormone synthesis
sbq04921  Oxytocin signaling pathway
sbq04923  Regulation of lipolysis in adipocytes
sbq04925  Aldosterone synthesis and secretion
sbq04926  Relaxin signaling pathway
sbq04927  Cortisol synthesis and secretion
sbq04928  Parathyroid hormone synthesis, secretion and action
sbq04934  Cushing syndrome
sbq04935  Growth hormone synthesis, secretion and action
sbq04970  Salivary secretion
sbq04971  Gastric acid secretion
sbq04972  Pancreatic secretion
sbq04976  Bile secretion
sbq05032  Morphine addiction
sbq05163  Human cytomegalovirus infection
sbq05166  Human T-cell leukemia virus 1 infection
sbq05200  Pathways in cancer
sbq05207  Chemical carcinogenesis - receptor activation
sbq05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:sbq00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    101034552 (ADCY8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101034552 (ADCY8)
   04371 Apelin signaling pathway
    101034552 (ADCY8)
   04020 Calcium signaling pathway
    101034552 (ADCY8)
   04072 Phospholipase D signaling pathway
    101034552 (ADCY8)
   04024 cAMP signaling pathway
    101034552 (ADCY8)
   04022 cGMP-PKG signaling pathway
    101034552 (ADCY8)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101034552 (ADCY8)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101034552 (ADCY8)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101034552 (ADCY8)
   04062 Chemokine signaling pathway
    101034552 (ADCY8)
  09152 Endocrine system
   04911 Insulin secretion
    101034552 (ADCY8)
   04923 Regulation of lipolysis in adipocytes
    101034552 (ADCY8)
   04912 GnRH signaling pathway
    101034552 (ADCY8)
   04913 Ovarian steroidogenesis
    101034552 (ADCY8)
   04915 Estrogen signaling pathway
    101034552 (ADCY8)
   04914 Progesterone-mediated oocyte maturation
    101034552 (ADCY8)
   04921 Oxytocin signaling pathway
    101034552 (ADCY8)
   04926 Relaxin signaling pathway
    101034552 (ADCY8)
   04935 Growth hormone synthesis, secretion and action
    101034552 (ADCY8)
   04918 Thyroid hormone synthesis
    101034552 (ADCY8)
   04928 Parathyroid hormone synthesis, secretion and action
    101034552 (ADCY8)
   04916 Melanogenesis
    101034552 (ADCY8)
   04925 Aldosterone synthesis and secretion
    101034552 (ADCY8)
   04927 Cortisol synthesis and secretion
    101034552 (ADCY8)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101034552 (ADCY8)
   04270 Vascular smooth muscle contraction
    101034552 (ADCY8)
  09154 Digestive system
   04970 Salivary secretion
    101034552 (ADCY8)
   04971 Gastric acid secretion
    101034552 (ADCY8)
   04972 Pancreatic secretion
    101034552 (ADCY8)
   04976 Bile secretion
    101034552 (ADCY8)
  09156 Nervous system
   04724 Glutamatergic synapse
    101034552 (ADCY8)
   04727 GABAergic synapse
    101034552 (ADCY8)
   04725 Cholinergic synapse
    101034552 (ADCY8)
   04720 Long-term potentiation
    101034552 (ADCY8)
   04723 Retrograde endocannabinoid signaling
    101034552 (ADCY8)
  09157 Sensory system
   04742 Taste transduction
    101034552 (ADCY8)
   04750 Inflammatory mediator regulation of TRP channels
    101034552 (ADCY8)
  09149 Aging
   04211 Longevity regulating pathway
    101034552 (ADCY8)
   04213 Longevity regulating pathway - multiple species
    101034552 (ADCY8)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101034552 (ADCY8)
   04714 Thermogenesis
    101034552 (ADCY8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101034552 (ADCY8)
   05207 Chemical carcinogenesis - receptor activation
    101034552 (ADCY8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101034552 (ADCY8)
   05163 Human cytomegalovirus infection
    101034552 (ADCY8)
  09165 Substance dependence
   05032 Morphine addiction
    101034552 (ADCY8)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    101034552 (ADCY8)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101034552 (ADCY8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101034552 (ADCY8)
Enzymes [BR:sbq01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     101034552 (ADCY8)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD
Other DBs
NCBI-GeneID: 101034552
NCBI-ProteinID: XP_003933787
UniProt: A0A2K6T6H4
Position
Unknown
AA seq 1196 aa
MELSDVRCLTGSEELYTIHPTPPAGEGRSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGS
GGSSKASDPAGGGPNHHAPQLSGDSALPLYSLGPGERTHSTCGTKVFPERSGSGSASGSG
GGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSE
VVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYL
QYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLL
QVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLR
LETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKG
FTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCC
VEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLES
GGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIV
KESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQS
GPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIV
LLFITAIQNLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETY
LARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVL
AMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEASL
LLMAMFLLAVFYHGQQELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEII
ADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQ
EINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEE
TYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAV
VLGLVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLSPSGTEPGAQPEGTDKSDLP
NT seq 3591 nt   +upstreamnt  +downstreamnt
atggagctctccgatgtgcgctgccttacaggcagcgaggaactctacaccatccacccg
acgcccccggccggcgaaggcaggagcggctcccggccgcagcggctgctgtggcagacg
gcggtgcggcacatcacggagcagcgcttcattcacgggcaccggggaggcggcgggagc
ggaggctcgagcaaagcctcggaccctgcgggcggcggccccaaccaccacgcgccgcag
ctgtcaggcgactccgcgctgcccctctactcgctcggccccggagagcgaacgcacagc
acctgcggcaccaaagtcttcccggaacgcagcgggagcggcagtgccagcggcagcgga
ggcgggggcgacttgggcttcctgcaccttgactgtgccccgagcaactcggatttcttc
ctcaacgggggctacagctacagaggggtcattttccccaccctgcgcaactccttcaag
tctcgggatctggagcgcctctaccagcgctatttcttgggccagaggcgcaaatcggaa
gtggtgatgaacgtgctggacgtgctcaccaaactcactctcttggtcctgcacttgagc
ctggcctcggccccgatggacccgctcaagggcatcctgctgggcttcttcaccggcatt
gaggtggtgatctgcgccctggtagtggtcaggaaagacaccacctcacacacgtacctg
cagtacagcggcgtggtcacctgggtggccatgaccacccagatcctggcagcaggcctc
ggctacgggctcctgggcgacggcataggctatgtgctcttcacgctcttcgccacctac
agcatgctgccgctgccgctcacctgggccatcctggccggcctgggcacctcgctgctg
caggtgatcctccaagtggtcatccctcggctggctgtcatttccatcaaccaggttgtg
gcccaggcagtgttattcatgtgtatgaacacagctggaatcttcatcagttacctgtca
gaccgggcccagcgccaagctttcctggagactcggaggtgtgtggaggccaggctgcgc
ctagagacagagaaccaaagacaggagcggctggttctctctgtgctcccccggtttgtt
gtcctggaaatgatcaatgacatgaccaatgtggaagacgagcacctgcagcaccagttc
catcggatctacatccatcgctatgagaatgtcagtattctttttgcagatgttaaagga
tttaccaacctctccacgaccttgtctgctcaggagctggtcaggatgctcaacgagctc
tttgccagatttgatcgactggcccatgagcatcactgccttcgtattaaaatcctgggg
gactgctactactgcgtgtccggacttcctgagccccgccaggaccatgcccactgctgt
gttgaaatgggtctcagcatgatcaaaaccatcaggtatgtgcggtcaaggacaaaacac
gatgttgacatgaggattggaatccactcaggctcggtgctgtgtggtgttttgggacta
aggaagtggcagtttgatgtctggtcttgggatgtggacattgcaaacaaactcgaatct
ggaggaatccctgggaggattcacatttccaaagccacactggactgtctcaacggtgac
tataatgtggaagagggtcatggtaaagagaggaatgaattcctgaggaagcataatata
gagacttatttaattaagcagcctgaggacagtctgctgtccttgcctgaagatattgtc
aaggagtcagtgagctcctcagaccggagaaacagtggggccacgttcactgaaggatcc
tggagccctgaactgccctttgataacatcgtggggaaacagaatactctggctgcccta
acaagaaattcaataaatctgcttccaaaccatcttgcacaagctttgcatgtccagtct
gggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagtggcgataaa
ttgagaagagagcatatcaagccattctcactgatgtttaaagactccagcctggagcat
aagtattctcaaatgagggatgaagtattcaagtcaaacttggtctgtgcatttatcgtt
cttctatttatcacggcaatacaaaatttgcttccttcttcaagagtgatgccaatgacc
atccagttctccattctgattatgctgcactcagctctggtcctcatcaccacggcagag
gattacaagtgtttgcccctcatcctccggaaaacttgctgttggattaatgaaacctat
ttggcccggaacgtcatcatctttgcatccatcttgattaattttctgggtgccatctta
aatatcctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttcaattcc
tcagctgtgtttacagatatctgctcctacccagagtactttgtcttcactggggtgttg
gccatggtgacctgtgcagttttcctccggctgaactccgtcctgaagctggcagtgttg
ctgatcatgatcgccatctacgccctgcttactgagaccatctatgcaggcctctttctg
cgttatgacaacctcaaccacagtggagaagatttcctggggaccaaggaggcctcgctg
ctactgatggccatgttccttctggctgtgttctaccatggacagcaggagctgtattct
caatcctacgacgctgtcggggtgatgtttgcctccatcccaggatttgcggacttttat
tctcagactgaaatgaataaccagggagtggaatgcctgcgcttgctgaatgagatcatt
gctgacttcgatgagttgcttggggaagaccgatttcaagacattgaaaagattaagacc
attggcagcacctacatggctgtgtcaggcctgtcacctgaaaaacagcaatgtgaagac
aaatggggacatttgtgtgctctggctgacttctcactcgccctgacagaaagcatacag
gagatcaacaagcattcattcaacaattttgagctccggattggcatcagccatggctca
gtggtagctggcgttatcggcgctaagaaaccacagtatgacatttggggcaaaactgtg
aacctggcaagccgaatggacagcacaggggttagtggccggatccaagtcccagaggag
acctatctcatcctgaaagatcagggctttgcctttgactaccgaggggagatctacgta
aaaggcattagtgaacaggaaggaaaaatcaaaacgtactttctcctgggaagagtccaa
cccaatccattcatcttgcccccaagaagactgcctgggcagtactccctggctgcagtc
gtcctgggactcgtccagtccctcaataggcaaaggcagaagcagctactcaatgagaac
aacaacacgggaattatcaagggtcattacaaccggcggactttgttgtcacccagcggg
acggagcctggagcccaacctgaaggcaccgacaaatctgatttgccataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (51)   
   KEGG PATHWAY (51)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (4)   
   Pfam (4)   
All databases (77)   

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