KEGG S.cerevisiae: YBR082C

Saccharomyces cerevisiae (budding yeast): YBR082C

Entry

YBR082C CDS S.cerevisiae

Gene name UBC4

Definition Ubc4p (EC:6.3.2.19)

Orthology K06689 ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19]

Pathway sce04120 Ubiquitin mediated proteolysis

Class Genetic Information Processing; Folding, Sorting and Degradation;
Ubiquitin mediated proteolysis [PATH:sce04120]

SSDB

Motif Pfam: UQ_con RWD UEV
PROSITE: UBIQUITIN_CONJUGAT_1 UBIQUITIN_CONJUGAT_2

Other DBs NCBI-GI: 6319556
NCBI-GeneID: 852376
SGD: S000000286
MIPS: YBR082C
UniProt: P15731

Structure

PDB: 1QCQ

Position II:complement(join(406622..407021,407117..407163))

AA seq 148 aa
MSSSKRIAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADSPYAGGVFFLSIHFPTD
YPFKPPKISFTTKIYHPNINANGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPL
VPEIAHIYKTDRPKYEATAREWTKKYAV

NT seq 447 nt +upstreamnt +downstreamnt
atgtcttcttctaaacgtattgctaaagaactaagtgatctagaaagagatccacctact
tcatgttcagccggtccagtcggcgatgatctatatcactggcaagcatccatcatggga
cctgccgattccccatatgccggcggtgttttcttcttgtctatccatttcccaaccgac
tacccattcaagccaccaaagatctccttcacaaccaagatatatcatccaaatatcaat
gccaatggtaacatctgtctggacatcctaaaggatcaatggtctccagctctaactcta
tcgaaggtcctattatccatctgttctttgttaacagacgctaatcctgacgatccttta
gtaccagaaatcgctcatatctacaagactgacagacccaagtacgaagctacagccaga
gaatggacaaagaaatacgctgtataa

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (4)   
   MIPS-SCE (1)   
   SGD-SCE (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (6)   
   GenBank (3)   
   EMBL (3)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (3)   
   PROSITE (2)   
All databases (25)

Schizosaccharomyces pombe (fission yeast): SPBC119.02

Entry

SPBC119.02 CDS S.pombe

Gene name ubc4

Definition ubiquitin conjugating enzyme Ubc4 (EC:6.3.2.19)

Orthology K06689 ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19]

Pathway spo04120 Ubiquitin mediated proteolysis

Class Genetic Information Processing; Folding, Sorting and Degradation;
Ubiquitin mediated proteolysis [PATH:spo04120]

SSDB

Motif Pfam: UQ_con RWD UEV
PROSITE: UBIQUITIN_CONJUGAT_1 UBIQUITIN_CONJUGAT_2

Other DBs NCBI-GI: 19112075
NCBI-GeneID: 2540083
GeneDB: SPBC119.02
UniProt: P46595

Position II

AA seq 147 aa
MALKRINRELADLGKDPPSSCSAGPVGDDLFHWQATIMGPADSPYAGGVFFLSIHFPTDY
PFKPPKVNFTTRIYHPNINSNGSICLDILRDQWSPALTISKVLLSICSLLTDPNPDDPLV
PEIAHVYKTDRSRYELSAREWTRKYAI

NT seq 444 nt +upstreamnt +downstreamnt
atggctttgaaaagaattaaccgtgaattagctgatcttggaaaagacccaccgtcttct
tgttccgccggccctgttggcgatgatttattccattggcaagctacaatcatgggtcct
gctgacagcccttatgcgggtggtgtcttcttcttgtccattcatttccctacggactac
ccattcaagccaccaaaggtaaactttacaaccagaatctatcatcccaacatcaattca
aacggtagcatttgtttggatatccttcgtgaccaatggtctccagcgttgactatatca
aaggtattactgtctatctgctcattgttgacagatcctaatcctgatgatccgcttgtg
cctgaaattgcgcacgtctacaaaactgacagatcccgttatgaattaagtgctcgtgaa
tggactagaaaatacgcaatctag

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
   GENEDB-SPO (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (5)   
   Pfam (3)   
   PROSITE (2)   
All databases (20)

Homo sapiens (human): 7322

Entry

7322 CDS H.sapiens

Gene name UBE2D2

Definition ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
(EC:6.3.2.19)

Orthology K06689 ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19]

Pathway hsa04120 Ubiquitin mediated proteolysis

Class Genetic Information Processing; Folding, Sorting and Degradation;
Ubiquitin mediated proteolysis [PATH:hsa04120]

SSDB

Motif Pfam: UQ_con RWD UEV
PROSITE: UBIQUITIN_CONJUGAT_1 UBIQUITIN_CONJUGAT_2

Other DBs NCBI-GI: 4507775
NCBI-GeneID: 7322
OMIM: 602962
HGNC: 12475
HPRD: 04268
Ensembl: ENSG00000131508
UniProt: P62837 Q96RP6

Structure

PDB: 2ESK 2ESQ 2ESO 2ESP 2CLW 2C4O 3A33 3JW0
3JVZ 1W4U 1UR6

Position 5q31.2

AA seq 147 aa
MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY
PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV
PEIARIYKTDREKYNRIAREWTQKYAM

NT seq 444 nt +upstreamnt +downstreamnt
atggctctgaagagaatccacaaggaattgaatgatctggcacgggaccctccagcacag
tgttcagcaggtcctgttggagatgatatgttccattggcaagctacaataatggggcca
aatgacagtccctatcagggtggagtatttttcttgacaattcatttcccaacagattac
cccttcaaaccacctaaggttgcatttacaacaagaatttatcatccaaatattaacagt
aatggcagcatttgtcttgatattctacgatcacagtggtctccagcactaactatttca
aaagtactcttgtccatctgttctctgttgtgtgatcccaatccagatgatcctttagtg
cctgagattgctcggatctacaaaacagatagagaaaagtacaacagaatagctcgggaa
tggactcagaagtatgcgatgtaa

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (7)   
   UniProt (2)   
   RefSeq(pep) (2)   
   IPI (3)   
DNA sequence (8)   
   RefSeq(nuc) (2)   
   GenBank (3)   
   EMBL (3)   
3D Structure (11)   
   PDB (11)   
Protein domain (5)   
   Pfam (3)   
   PROSITE (2)   
All databases (46)

Homo sapiens (human): 7323

Entry

7323 CDS H.sapiens

Gene name UBE2D3

Definition ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
(EC:6.3.2.19)

Orthology K06689 ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19]

Pathway hsa04120 Ubiquitin mediated proteolysis

Class Genetic Information Processing; Folding, Sorting and Degradation;
Ubiquitin mediated proteolysis [PATH:hsa04120]

SSDB

Motif Pfam: UQ_con RWD UEV
PROSITE: UBIQUITIN_CONJUGAT_1 UBIQUITIN_CONJUGAT_2

Other DBs NCBI-GI: 4507777
NCBI-GeneID: 7323
OMIM: 602963
HGNC: 12476
HPRD: 04269
Ensembl: ENSG00000109332
UniProt: P61077

Structure

PDB: 1X23 2FUH

Position 4q24

AA seq 147 aa
MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY
PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV
PEIARIYKTDRDKYNRISREWTQKYAM

NT seq 444 nt +upstreamnt +downstreamnt
atggcgctgaaacggattaataaggaacttagtgatttggcccgtgaccctccagcacaa
tgttctgcaggtccagttggggatgatatgtttcattggcaagccacaattatgggacct
aatgacagcccatatcaaggcggtgtattctttttgacaattcattttcctacagactac
cccttcaaaccacctaaggttgcatttacaacaagaatttatcatccaaatattaacagt
aatggcagcatttgtctcgatattctaagatcacagtggtcgcctgctttaacaatttct
aaagttcttttatccatttgttcactgctatgtgatccaaacccagatgaccccctagtg
ccagagattgcacggatctataaaacagacagagataagtacaacagaatatctcgggaa
tggactcagaagtatgccatgtga

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (12)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (14)   
   UniProt (1)   
   RefSeq(pep) (9)   
   IPI (4)   
DNA sequence (15)   
   RefSeq(nuc) (9)   
   GenBank (3)   
   EMBL (3)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (3)   
   PROSITE (2)   
All databases (58)

Homo sapiens (human): 7324

Entry

7324 CDS H.sapiens

Gene name UBE2E1

Definition ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
(EC:6.3.2.19)

Orthology K06689 ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19]

Pathway hsa04120 Ubiquitin mediated proteolysis

Class Genetic Information Processing; Folding, Sorting and Degradation;
Ubiquitin mediated proteolysis [PATH:hsa04120]

SSDB

Motif Pfam: UQ_con RWD SR-25
PROSITE: UBIQUITIN_CONJUGAT_1 UBIQUITIN_CONJUGAT_2

Other DBs NCBI-GI: 4507779
NCBI-GeneID: 7324
OMIM: 602916
HGNC: 12477
HPRD: 04225
Ensembl: ENSG00000170142
UniProt: B2RBX4 P51965

Structure

PDB: 3BZH

Position 3p24.3-p24.2

AA seq 193 aa
MSDDDSRASTSSSSSSSSNQQTEKETNTPKKKESKVSMSKNSKLLSTSAKRIQKELADIT
LDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIY
HCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEH
DRMARQWTKRYAT

NT seq 582 nt +upstreamnt +downstreamnt
atgtcggatgacgattcgagggccagcaccagctcctcctcatcttcgtcttccaaccag
caaaccgagaaagaaacaaacacccccaagaagaaggagagtaaagtcagcatgagcaaa
aactccaaactcctctccaccagcgccaagagaattcagaaggagctggcggacatcact
ttagaccctccacctaattgcagtgctggtcccaaaggcgataacatctatgaatggaga
tcaaccattctagggcctccaggatccgtgtatgagggtggtgtattctttctcgatatc
acttttacaccagaatatcccttcaagcctccaaaggttacatttcggacaagaatctat
cattgtaatattaacagtcaaggtgttatttgcttggacatattgaaagataattggagt
ccagcactaaccatttctaaagtcctcctttctatctgctcacttcttacagactgtaat
cctgccgaccccttggtgggaagtattgccactcagtatatgaccaacagagcagaacat
gacagaatggccagacagtggaccaagagatacgctacataa

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (6)   
   UNIGENE (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (10)   
   UniProt (2)   
   RefSeq(pep) (2)   
   IPI (6)   
DNA sequence (8)   
   RefSeq(nuc) (2)   
   GenBank (3)   
   EMBL (3)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (3)   
   PROSITE (2)   
All databases (40)

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