KEGG   Saccharomyces cerevisiae (budding yeast): YER178W
Entry
YER178W           CDS       T00005                                 
Symbol
PDA1
Name
(RefSeq) pyruvate dehydrogenase (acetyl-transferring) subunit E1 alpha
  KO
K00161  pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce00010  Glycolysis / Gluconeogenesis
sce00020  Citrate cycle (TCA cycle)
sce00620  Pyruvate metabolism
sce00785  Lipoic acid metabolism
sce01100  Metabolic pathways
sce01110  Biosynthesis of secondary metabolites
sce01200  Carbon metabolism
sce01210  2-Oxocarboxylic acid metabolism
Module
sce_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:sce00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    YER178W (PDA1)
   00020 Citrate cycle (TCA cycle)
    YER178W (PDA1)
   00620 Pyruvate metabolism
    YER178W (PDA1)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    YER178W (PDA1)
Enzymes [BR:sce01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     YER178W (PDA1)
SSDB
Motif
Pfam: E1_dh DXP_synthase_N KRTAP7
Other DBs
NCBI-GeneID: 856925
NCBI-ProteinID: NP_011105
SGD: S000000980
UniProt: P16387
Position
V:546817..548079
AA seq 420 aa
MLAASFKRQPSQLVRGLGAVLRTPTRIGHVRTMATLKTTDKKAPEDIEGSDTVQIELPES
SFESYMLEPPDLSYETSKATLLQMYKDMVIIRRMEMACDALYKAKKIRGFCHLSVGQEAI
AVGIENAITKLDSIITSYRCHGFTFMRGASVKAVLAELMGRRAGVSYGKGGSMHLYAPGF
YGGNGIVGAQVPLGAGLAFAHQYKNEDACSFTLYGDGASNQGQVFESFNMAKLWNLPVVF
CCENNKYGMGTAASRSSAMTEYFKRGQYIPGLKVNGMDILAVYQASKFAKDWCLSGKGPL
VLEYETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIAGLKMHLIDLGIATEAEVKAYDK
SARKYVDEQVELADAAPPPEAKLSILFEDVYVKGTETPTLRGRIPEDTWDFKKQGFASRD
NT seq 1263 nt   +upstreamnt  +downstreamnt
atgcttgctgcttcattcaaacgccaaccatcacaattggtccgcgggttaggagctgtt
cttcgcactcccaccaggataggtcatgttcgtaccatggcaactttaaaaacaactgat
aagaaggcccctgaggacatcgagggctcggacacagtgcaaattgagttgcctgaatct
tccttcgagtcgtatatgctagagcctccagacttgtcttatgagacttcgaaagccacc
ttgttacagatgtataaagatatggtcatcatcagaagaatggagatggcttgtgacgcc
ttgtacaaggccaagaaaatcagaggtttttgccatctatctgttggtcaggaggccatt
gctgtcggtatcgagaatgccatcacaaaattggattccatcatcacatcttacagatgt
cacggtttcacttttatgagaggtgcctcagtgaaagccgttctggctgaattgatgggt
agaagagccggtgtctcttatggtaagggtggttccatgcacctttacgctccaggcttc
tatggtggtaatggtatcgtgggtgcccaggttcctttaggtgcaggtttagcttttgct
caccaatacaagaacgaggacgcctgctctttcactttgtatggtgatggtgcctctaat
caaggtcaagtttttgaatctttcaacatggccaaattatggaatttgcccgtcgtgttt
tgctgtgagaacaacaagtacggtatgggtaccgccgcttcaagatcctccgcgatgact
gaatatttcaagcgtggtcaatatattccaggtttaaaagttaacggtatggatattcta
gctgtctaccaagcatccaagtttgctaaggactggtgtctatccggcaaaggtcctctc
gttctagaatatgaaacctataggtacggtggccattctatgtctgatcccggtactacc
tacagaactagagacgagattcagcatatgagatccaagaacgatccaattgctggtctt
aagatgcatttgattgatctaggtattgccactgaagctgaagtcaaagcttacgacaag
tccgctagaaaatacgttgacgaacaagttgaattagctgatgctgctcctcctccagaa
gccaaattatccatcttgtttgaagacgtctacgtgaaaggtacagaaactccaacccta
agaggtaggatccctgaagatacttgggacttcaaaaagcaaggttttgcctctagggat
taa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (46)   

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