KEGG   Streptomyces collinus: B446_25775
Entry
B446_25775        CDS       T02787                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
sci  Streptomyces collinus
Pathway
sci03030  DNA replication
sci03410  Base excision repair
sci03420  Nucleotide excision repair
sci03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:sci00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    B446_25775 (ligA)
   03410 Base excision repair
    B446_25775 (ligA)
   03420 Nucleotide excision repair
    B446_25775 (ligA)
   03430 Mismatch repair
    B446_25775 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:sci03032]
    B446_25775 (ligA)
   03400 DNA repair and recombination proteins [BR:sci03400]
    B446_25775 (ligA)
Enzymes [BR:sci01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     B446_25775 (ligA)
DNA replication proteins [BR:sci03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     B446_25775 (ligA)
DNA repair and recombination proteins [BR:sci03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     B446_25775 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     B446_25775 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     B446_25775 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      B446_25775 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD PTCB-BRCT HHH_5 HMBD zf-TFIIB
Other DBs
NCBI-ProteinID: AGS71963
UniProt: S5UXJ5
Position
5928506..5930701
AA seq 731 aa
MAGDKQARTTAVPAEAREKHTRLAEQVEEHRFRYYVKDAPVVSDAEFDKLLKTLEALEAE
YPELRTPDSPTQKVAGSYATEFTAVEHRQRMLSLDNTFNDDDLAAWADRIARELGEQEYH
FLCELKVDGLAVNLTYEHGRLTRAATRGDGRTGEDITPNVRTIAEIPDRLKGDDVPDLVE
IRGEVYFPMEKFLELNARLVAAGDKPFANPRNAAAGSLRQKDPRVTATRPLHMVVHGIGA
LEGFSGMTRLSQAYDLLKTWGLPTSPHNRVVDDLDGVRAFIAYYGENRHSVAHEIDGAVI
KLDEIRLQGRLGSTARAPRWAIAYKYAPEEVNTKLIDIKVGVGRTGRVTPYAQVEPVTVA
GSEVEFATLHNQEVVKAKGVLIGDTVVLRKAGDVIPEILGPVADLRDGSEREFVMPGECP
ECGTALRPMKEGDIDLRCPNARACPAQLRGRLSYLAGRECLDIEHFGDVAAAALTQPLEP
ADPPLVDEGDLFDLTVEKLLPIKAYVLDPDSGLPKRDPKTGEEKVVTVFANQKGEPKKNT
LALLENIEAAKSRPLARFLNGLSIRHVGPVAAQALAREFRSLDRIEQATEVELAGTDGVG
PIIAAALKEWFAEEWHREIVRKWKAAGVPLEDQASGEDEGPRPLEGLTVVVTGTLENFTR
DGAKDALQSRGAKVTGSVSKKTSFVVVGDNPGSKYDKAMQLKVPVLNEDGFAVLLERGPE
AAAEVALPSAE
NT seq 2196 nt   +upstreamnt  +downstreamnt
gtggccggcgacaagcaagcccggacgacggcggtgcccgccgaggcccgcgagaagcac
acgcggctcgcggagcaggtcgaggagcaccgcttccggtactacgtgaaggacgctccc
gtcgtcagcgacgcggagttcgacaagctcctgaagacgctggaggcgctggaggcggag
taccccgagctgcgcaccccggactcgcccacccagaaggtcgccgggtcgtacgccacg
gagttcaccgccgtcgagcaccgccagcggatgctctccctggacaacaccttcaacgac
gacgacctggccgcctgggccgaccgcatcgcgcgggaactgggcgagcaggagtaccac
ttcctgtgcgagctgaaggtcgacggcctcgcggtcaacctcacctacgagcacggccgt
ctcacccgcgcggccacccgcggcgacggccgcaccggcgaggacatcaccccgaacgtc
cgcacgatcgcggagatcccggaccgcctcaagggcgacgacgtcccggacctggtcgag
atccgcggcgaggtctacttcccgatggagaagttcctcgagctgaacgcacgcctggtc
gcagcgggagacaagcccttcgccaacccccgcaacgcggcggccggttcgctgcggcag
aaggacccgcgggtcaccgccacccggccgctgcacatggtcgtccacggcatcggcgcc
ctggagggcttctcgggcatgacccgcctctcccaggcctacgacctgctgaagacctgg
ggactgccgacctccccgcacaaccgcgtggtcgacgacctcgacggcgtccgcgcgttc
atcgcctactacggcgagaaccgccactccgtggcgcacgagatcgacggcgccgtcatc
aagctcgacgagatccgcctccagggccgcctgggctccaccgcgcgcgccccgcgctgg
gcgatcgcctacaagtacgcgccggaggaggtcaacaccaagctcatcgacatcaaggtg
ggggtcggccgcaccggccgggtcacgccgtacgcccaggtcgagccggtcaccgtcgcg
ggcagcgaggtcgagttcgccaccctgcacaaccaggaggtcgtcaaggccaagggcgtg
ctcatcggcgacaccgtcgtgctgcgcaaggccggtgacgtcatcccggagatcctcggc
cccgtggccgacctgcgggacggcagcgagcgggagttcgtgatgccgggcgagtgcccc
gagtgcggcacggcgctgcggcccatgaaggagggcgacatcgacctccgctgccccaac
gcccgtgcctgccctgcccagttgcgcggacgcctgtcctacctcgcgggccgcgagtgc
ctggacatcgagcacttcggcgacgtggccgcggccgcgctcacccagccgctggagccg
gccgacccgccgctggtcgacgagggcgacctgttcgacctgacggtggagaagctgctg
cccatcaaggcctacgtcctcgacccggacagcgggctgcccaagcgggacccgaagacg
ggcgaggagaaggtcgtcacggtcttcgccaaccagaagggcgagccgaagaagaacacc
ctcgccctcctggagaacatcgaggcggccaagtcccgcccgctcgcccgcttcctgaac
gggctgtccatccggcacgtcggcccggtcgccgcgcaggccctcgcccgcgagttccgc
tcgctcgaccgcatcgagcaggccaccgaggtggagctggccggcacggacggcgtcggc
cccatcatcgccgccgccctcaaggagtggttcgccgaggagtggcaccgcgagatcgtc
cgcaagtggaaggcggccggagtcccgctggaggaccaggcctcgggcgaggacgagggg
ccgcgtccgctggaggggctcaccgtcgtcgtcaccggcaccctggagaacttcacgcgg
gacggcgccaaggacgcgctgcagagccgcggcgcgaaggtgaccggatcggtgtcgaag
aagacctcgttcgtggtggtcggcgacaacccggggtcgaagtacgacaaggcgatgcag
ctcaaggtcccggtcctgaacgaggacggtttcgccgtcctgttggagcggggacccgag
gccgcggccgaagtcgcgcttccctccgccgagtag

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (9)   
   Pfam (9)   
All databases (29)   

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