KEGG T01646: SCAT

Streptomyces cattleya NRRL 8057: SCAT_4386

Entry

SCAT_4386 CDS T01646

Gene name

leuC

Definition

3-isopropylmalate dehydratase large subunit

Orthology

K01703

3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]

Organism

sct Streptomyces cattleya NRRL 8057

Pathway

sct00290	Valine, leucine and isoleucine biosynthesis
sct00660	C5-Branched dibasic acid metabolism
sct01100	Metabolic pathways
sct01110	Biosynthesis of secondary metabolites
sct01210	2-Oxocarboxylic acid metabolism
sct01230	Biosynthesis of amino acids

Module

sct_M00432

Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

Class

Metabolism; Carbohydrate metabolism; C5-Branched dibasic acid metabolism [PATH:sct00660]
Metabolism; Amino acid metabolism; Valine, leucine and isoleucine biosynthesis [PATH:sct00290]

SSDB

Motif

Pfam:

Aconitase

Other DBs

NCBI-GI:

357401960

NCBI-GeneID:

11358714

UniProt:

F8JSL8

Position

4703888..4705312

AA seq 474 aa
MGRTLAEKVWDDHVVRRADGEPDLLYIDLHLLHEVTSPQAFDGLRLSGRTVRRTDLTIAT
EDHNTPTLDIDKPIADPVSRTQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPMAPFRTMAITVDGELPDGVTA
KDLILAIIARIGTGGGQGYVIEYRGQAIEKLSMEARMTVCNMSIEAGARAGMIAPDETTF
AYLEGRPHAPKGADWDAAVAYWRTLRTDEDAVFDHEVYIDAAELSPFVTWGTNPGQGAPL
SASVPDPASFDDPSERLAAEKALEYMGLTAGTPLRDVAVDTVFVGSCTNGRIEDLRAAAA
VLQGRKVADGVRMLVVPGSVRVALQAVEEGLDKVFTAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVTGHLASPADLAKAPVTVEV

NT seq 1425 nt +upstreamnt +downstreamnt
atgggacggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgatggc
gagccggaccttctctacatcgatctgcatctgctgcacgaggtgaccagtccgcaggcg
ttcgacggactgcggctcagcgggcgtacggtccgccggaccgacctgaccatcgcgacc
gaggaccacaacaccccgacgctcgacatcgacaagccgatcgccgacccggtctcccgc
acccagttggagacgctgcgcaagaactgcgcggagttcggggtgcggctgcacccgctc
ggtgacgtcgagcagggcgtggtgcacgtggtcggtccgcagttggggctgacccagccg
ggcaccacggtggtctgcggcgacagccacacctccacgcacggcgcgttcggcgcgctc
gccttcggcatcggcaccagccaggtcgagcacgtgctggccacccagacgctgccgatg
gcgccgttcaggaccatggcgatcaccgtcgacggcgagctgccggacggcgtcaccgcc
aaggacctgatcctggcgatcatcgcccggatcggcaccggcggcggccaggggtacgtg
atcgaataccgcggccaggccatcgagaagctctcgatggaggcccggatgaccgtgtgc
aacatgtccatcgaggcgggcgcccgggccggcatgatcgcgccggacgagaccacgttc
gcctacctggaagggcgcccgcacgcgcccaagggcgccgactgggacgccgcggtggcg
tactggaggacgctgcgcaccgacgaggacgccgtcttcgaccacgaggtctacatcgac
gccgccgagctgtccccgttcgtgacctggggcaccaacccgggccagggcgcgccgctg
tcggcctcggtgcccgacccggcctcgttcgacgaccccagcgagcggctggccgccgag
aaggcgctggaatacatggggctgaccgcggggacgccgctgcgcgacgtcgcggtggac
accgtcttcgtcggatcgtgcaccaacggccggatcgaggacctgcgggccgccgccgcg
gtgcttcaggggcgcaaggtcgccgacggggtgcggatgctggtggtccccggctcggta
cgggtggcgctccaggccgtcgaggaggggctggacaaggtgttcaccgcggccggcgcc
gaatggcggcacgcgggttgctcgatgtgcctgggcatgaacccggaccaactggcgccc
ggcgagcgttccgcctccacctccaaccgcaacttcgaggggcggcagggcaagggcgga
cgcacccacctggtctccccgcaggtcgccgcggccaccgcggtcaccggccacctggcg
tccccggccgacctggccaaagcccctgtcaccgtggaggtctga

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (7)   
   KEGG ENZYME (2)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (1)   
   Pfam (1)   
All databases (29)   

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