KEGG   Streptomyces cyaneogriseus: TU94_18645
Entry
TU94_18645        CDS       T03687                                 
Name
(GenBank) porphobilinogen deaminase
  KO
K01749  hydroxymethylbilane synthase [EC:2.5.1.61]
Organism
scw  Streptomyces cyaneogriseus
Pathway
scw00860  Porphyrin metabolism
scw01100  Metabolic pathways
scw01110  Biosynthesis of secondary metabolites
scw01120  Microbial metabolism in diverse environments
scw01240  Biosynthesis of cofactors
Module
scw_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
scw_M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:scw00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    TU94_18645
Enzymes [BR:scw01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.61  hydroxymethylbilane synthase
     TU94_18645
SSDB
Motif
Pfam: Porphobil_deam Porphobil_deamC NMT1 DUF6013 CoA_binding_3 SBP_bac_3
Other DBs
NCBI-ProteinID: AJP03194
UniProt: A0A0C5G4P3
Position
4425873..4426835
AA seq 320 aa
MTEKALRLGTRRSKLAMAQSGQVADAVSQVTGRPVELVEITTYGDTSREHLAQIGGTGVF
VTALRDALLRGEVDFAVHSLKDLPTAQPEDLVLAAVPVREDPRDVIVARDARKFADLPPG
ARVGTGSPRRMAQLNAYARSHGLDIETVPIRGNVDTRIGYVRSGELDAVVLAAAGMNRIG
RIDEVTDFLSVDTVLPAPGQGALAIECAAADAELIAVLAELDDPFTRAAVTAERSLLAAL
EAGCSAPVGALADLPHADGQIVKEMRLRGVVGTTDGTALVQLSTTGPVPVTHEEAVALGR
ELAAEMLAQGAAGLMGERAH
NT seq 963 nt   +upstreamnt  +downstreamnt
atgactgagaaggcactgaggctggggaccaggcgcagcaagctcgccatggcccagtcc
gggcaggtggcggacgccgtgagccaggtgaccgggcggcccgtcgagctcgtcgagatc
accacgtacggtgacacgtcgcgcgagcacctggcgcagatcggcggcacgggcgtgttc
gtgaccgcgctgcgcgacgcgctgctgaggggcgaggtggacttcgcggttcattcgctc
aaggacctgccgacggcgcagcccgaggacctggtcctggccgccgtaccggtgcgcgag
gacccgcgggacgtgatcgtcgcccgggacgcgcggaagttcgcggacctgccgcccggg
gcgcgtgtgggcacgggttcgccgcgccgcatggcgcagctcaacgcgtacgcgcgcagc
cacgggctggacatcgagacggtcccgatccggggcaacgtcgacacgcggatcgggtac
gtccgcagcggtgagctggacgccgtcgtgctcgccgccgccgggatgaaccggatcggc
cggatcgacgaggtgaccgacttcctgtcggtcgacacggttctgccggcccccggccag
ggggccctggcgatcgagtgcgccgcggccgacgcggagctgatcgccgtgctcgcggag
ctcgacgacccgttcacgcgggccgccgtgaccgccgagcggtcactgctcgccgccctg
gaggccggctgcagcgcccctgtgggagcgctggccgaccttccccatgccgacgggcaa
attgtcaaggaaatgcgcctgcggggcgtcgtcggcacgaccgacggcaccgcgctggtg
cagctgtccaccaccggtcccgtgcccgtgacgcacgaggaggccgtggcactcggccgc
gaactcgccgccgagatgctcgcccagggcgcggccggtctgatgggggagcgagcacat
tga

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